Orchestra BioMed Holdings OBIO
NASDAQ OBIO
$5.10 +0.36 (+7.59%)
As of: Sep 4, 2026 · 3:21 PM EDT

Orchestra BioMed Holdings (OBIO) Profit After Tax (2021 - 2026)

Orchestra BioMed Holdings (OBIO) posted quarterly Profit After Tax of -$20.7 million for Q1 2026, down 10.32% year-over-year from -$23.1 million in Q1 2025, and down 430.53% quarter-over-quarter from $6.3 million in Q4 2025.

Analysis

Orchestra BioMed Holdings (OBIO) Profit After Tax (2021 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has reported Profit After Tax for 6 consecutive years, with -$20.7 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Profit After Tax fell 10.32% year-over-year to -$20.7 million; the TTM figure through Mar 2026 stood at -$54.6 million (up 17.66% YoY), while the FY2025 annual figure was -$52.7 million, up 13.65% from the prior year.
  • Profit After Tax fell to -$20.7 million in Q1 2026 per OBIO's latest filing, from $6.3 million in the prior quarter.
  • Across five years, Profit After Tax topped out at $6.3 million in Q4 2025 and bottomed at -$20.8 million in Q3 2025.
  • Historically, Profit After Tax has averaged -$12.8 million across 5 years, with a median of -$13.3 million in 2023.
  • Annual changes were most pronounced in 2022 — Profit After Tax sank 11272.51% — and 2025, when it jumped 138.49%.
  • Orchestra BioMed Holdings' Profit After Tax stood at -$9.8 million in 2022, then sank by 31.47% to -$12.8 million in 2023, then retreated by 26.88% to -$16.3 million in 2024, then surged by 138.49% to $6.3 million in 2025, then plunged by 430.53% to -$20.7 million in 2026.
  • Business Quant data shows OBIO's Profit After Tax at -$20.7 million in Q1 2026, $6.3 million in Q4 2025, and -$20.8 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) PAT (Qtr)
1 Vertex Pharmaceuticals 138.43 Bn 130.58 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 63.34 Bn 58.15 Bn 1.37 Bn 472.00 Mn
4 Moderna 57.98 Bn 52.85 Bn 52.00 Mn -782.00 Mn
5 Revolution Medicines 43.98 Bn 43.98 Bn - -644.37 Mn
6 BeOne Medicines 39.92 Bn 34.82 Bn 1.53 Bn 237.01 Mn
7 Alnylam Pharmaceuticals 35.42 Bn 32.11 Bn 992.69 Mn 164.49 Mn
8 Royalty Pharma 28.42 Bn 27.58 Bn - 81.49 Mn
9 Insmed 27.36 Bn 26.20 Bn 358.27 Mn -16.62 Mn
10 Orchestra BioMed Holdings 324.80 Mn 130.27 Mn 63,000.00 -23.80 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -23.80 Mn
Mar 31, 2026 -20.69 Mn
Dec 31, 2025 6.25 Mn
Sep 30, 2025 -20.83 Mn
Jun 30, 2025 -19.38 Mn
Mar 31, 2025 -18.76 Mn
Dec 31, 2024 -16.16 Mn
Sep 30, 2024 -15.43 Mn
Jun 30, 2024 -15.98 Mn
Mar 31, 2024 -13.46 Mn
Dec 31, 2023 -12.75 Mn
Sep 30, 2023 -13.32 Mn
Jun 30, 2023 -12.05 Mn
Mar 31, 2023 -10.94 Mn
Dec 31, 2022 -9.76 Mn
Sep 30, 2022 -10.28 Mn
Jun 30, 2022 -7.85 Mn
Mar 31, 2022 -5.73 Mn
Dec 31, 2021 -88,011.00
Sep 30, 2021 -90,411.00