Orchestra BioMed Holdings OBIO Insider Ownership

NASDAQ OBIO

$5.80 -0.02 (-0.26%)

At close: Oct 21, 2026 · 4:00 PM EDT

Insider Holdings by Owner

32.52Mn Shares

Insider Ownership Statistics

as of 30 Sep, 2026

Insider Ownership

42.08%

▼-2.78% pp QoQ

Shares Held by Insiders

26.85Mn

filed for Sep 2026

▼-6.19% QoQ

Shares Outstanding

63.81Mn

63,812,098 shares

Direct Holdings

3.15Mn

Indirect: 23.70Mn

Net Shares Traded (QoQ)

-1.77Mn

net selling in Sep 2026

Insiders Holding Shares

with Form 4 holdings on file

Shares Owned by Insiders

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Insiders

Bought Sold

Latest quarter —

Net over range —

Buying quarters —

Insider Ownership Summary

Updated Oct 10, 2026

Over the trailing 12 months, OBIO insiders bought $279,891 worth of shares (66.64K shares) and sold $353,082 worth (75.03K shares) in open-market trades.

Orchestra BioMed Holdings' open-market purchases in the past 12 months came from 4 insiders, and its sales from 2 insiders.
Among Orchestra BioMed Holdings' insiders, David P. Hochman (Director and officer) was the largest open-market buyer over the past 12 months, purchasing $149,150 of stock (35K shares), most recently on September 3, 2026.
Meanwhile, the largest open-market sales of OBIO in the past 12 months were by Darren Sherman (Director and officer), totaling $352,950 (75K shares), most recently on October 1, 2026.
Apart from open-market trades, OBIO insiders received 1.15Mn shares in stock awards, acquired 1.25Mn shares through option exercises and conversions and gave up 273.51K shares to cover taxes or exercise prices in the past 12 months.
Business Quant data shows Orchestra BioMed Holdings insiders holding 26.84Mn shares in total in their latest Form 4 filings, down 6.24% from 28.62Mn shares at the end of Q2 2026 and up 10.71% from 24.24Mn shares at the end of Q3 2025.
Direct holdings account for 3.14Mn shares (11.69%) of OBIO's insider total, and indirect holdings through trusts, partnerships and family members for 23.7Mn shares (88.31%).
OBIO's insider total is spread across 12 insiders who have filed a Form 4 in the past two years.
OBIO's three largest insider shareholders, per their latest Form 4 filings, are RTW Investments, LP (10% owner, 17.86Mn shares), Perceptive Advisors LLC (10% owner, 5.29Mn shares) and David P. Hochman (Director and officer, 1.51Mn shares).
The largest insider, RTW Investments, LP, holds 66.56% of OBIO's insider total.
Institutional investors held 43.38% of Orchestra BioMed Holdings stock at the end of Q2 2026, while the latest Form 4 filings of its insiders account for about 42.05%; other investors, including the public, hold roughly 14.57%.
In the last 12 months, 49 Form 4 filings with transactions in OBIO stock came from 11 insiders.
Insider figures for OBIO include Form 4 filings through October 2, 2026.

Form 4 Holdings

Insiders Holding OBIO

Insiders 21

Shares held 32.52Mn

Of outstanding 50.96%

#	Insider	Position	Direct	Indirect	Total	Share of Insiders	Last Filed
1	Investments, Lp Rtw	TenPercentOwner	0	9,556,063	9,556,063	29.4%	29 Apr, 2026
2	Advisors Llc Perceptive	TenPercentOwner	0	5,292,556	5,292,556	16.3%	05 Aug, 2025
3	Plc Medtronic	TenPercentOwner	0	4,999,423	4,999,423	15.4%	01 Feb, 2023
4	Roderick Wong	Chief Executive Officer	0	2,808,512	2,808,512	8.6%	26 Jan, 2023
5	Darren Sherman	Director, Officer	2,273,729	2,000	2,275,729	7.0%	02 Oct, 2026
6	2 Holdings, Llc Hsac	TenPercentOwner	1,705,705	0	1,705,705	5.2%	07 Aug, 2024
7	Geoffrey Wade Smith	Director	24,401	1,507,166	1,531,567	4.7%	24 Jul, 2023
8	David P Hochman	Director, Officer	1,067,463	432,916	1,500,379	4.6%	11 Sep, 2026
9	Andrew Lawrence Taylor	Chief Financial Officer	1,070,777	0	1,070,777	3.3%	28 Aug, 2026
10	Eric S Fain	Director	0	313,441	313,441	1.0%	14 Aug, 2026
11	William Reed Little	Officer	307,859	0	307,859	0.9%	03 Jun, 2024
12	Jason Aryeh	Director	225,600	0	225,600	0.7%	20 May, 2026
13	John Prosper Mack	Director	212,912	0	212,912	0.7%	14 Aug, 2026
14	David Pacitti	Director	175,556	0	175,556	0.5%	14 Aug, 2026
15	Michael Kaswan	Chief Financial Officer	162,574	0	162,574	0.5%	05 May, 2023
16	Yuval Mika	Officer	158,905	0	158,905	0.5%	10 May, 2024
17	Chris Cleary	Director	66,054	0	66,054	0.2%	14 Aug, 2026
18	Pamela Ann Connealy	Director	66,038	0	66,038	0.2%	25 Jun, 2026
19	George Papandreou	Officer	42,000	0	42,000	0.1%	10 May, 2024
20	Joshua Aiello	Principal Accounting Officer	37,085	0	37,085	0.1%	28 Aug, 2026
21	Eric A Md Rose	Director	9,712	0	9,712	0.0%	21 Jun, 2024

Each row is that insider’s most recently reported position, from Form 4 filings over the last 60 months — which is why this total does not tie to the quarterly series above, where a quarter counts only the insiders who filed in it. Shares held through a fund or institutional portfolio are counted on the institutional ownership page instead.

Form 4 Filings

282 Insider Transactions

Source SEC Form 4

Latest quarter Sep 2026

Date	Insider	Position	Transaction	Shares	Price	Value	Shares Held After	Ownership
01 Oct, 2026	Darren Sherman	Director, Officer	Disposed S	15,000	$6.36	$95.40K	1,119,402	Direct
10 Sep, 2026	David P Hochman	Director, Officer	Disposed F	3,283	$5.81	$19.07K	1,067,463	Direct
10 Sep, 2026	David P Hochman	Director, Officer	Disposed F	3,283	$5.81	$19.07K	432,916	Indirect
03 Sep, 2026	David P Hochman	Director, Officer	Acquired P	10,000	$4.79	$47.90K	1,070,746	Direct
01 Sep, 2026	Darren Sherman	Director, Officer	Disposed S	15,000	$4.94	$74.10K	1,134,402	Direct
26 Aug, 2026	Darren Sherman	Director, Officer	Disposed F	4,925	$5.26	$25.91K	1,149,402	Direct
26 Aug, 2026	Andrew Lawrence Taylor	Chief Financial Officer	Disposed F	3,076	$5.26	$16.18K	589,989	Direct
26 Aug, 2026	Joshua Aiello	Principal Accounting Officer	Disposed F	203	$5.26	$1.07K	18,441	Direct
26 Aug, 2026	Darren Sherman	Director, Officer	Acquired P	2,000	$5.33	$10.66K	2,000	Indirect
12 Aug, 2026	David Pacitti	Director	Disposed F	3,761	$4.42	$16.62K	54,750	Direct
12 Aug, 2026	Chris Cleary	Director	Disposed F	4,238	$4.42	$18.73K	29,153	Direct
12 Aug, 2026	Eric S Fain	Director	Disposed F	5,145	$4.42	$22.74K	99,630	Indirect
12 Aug, 2026	John Prosper Mack	Director	Disposed F	4,885	$4.42	$21.59K	66,544	Direct
03 Aug, 2026	Darren Sherman	Director, Officer	Disposed S	15,000	$4.09	$61.35K	1,154,327	Direct
01 Jul, 2026	Darren Sherman	Director, Officer	Disposed S	15,000	$4.27	$64.05K	1,169,327	Direct
23 Jun, 2026	Pamela Ann Connealy	Director	Acquired A	17,327	$0.00	$0	66,038	Direct
23 Jun, 2026	David Pacitti	Director	Acquired A	17,327	$0.00	$0	62,295	Direct
23 Jun, 2026	Jason Aryeh	Director	Acquired A	42,553	$0.00	$0	42,553	Direct
23 Jun, 2026	Eric S Fain	Director	Acquired A	17,327	$0.00	$0	109,036	Indirect
23 Jun, 2026	John Prosper Mack	Director	Acquired A	34,653	$0.00	$0	74,939	Direct

Showing 1 to 20 of 282 transactions