Orchestra BioMed Holdings (OBIO) Net Income (2021 - 2026)

Orchestra BioMed Holdings (OBIO) posted quarterly Net Income of -$24.8 million for Q1 2026, down 27.72% year-over-year from -$34.2 million in Q1 2025, and down 487.22% quarter-over-quarter from $6.4 million in Q4 2025.

Orchestra BioMed Holdings (OBIO) Net Income (2021 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has reported Net Income for 6 consecutive years, with -$24.8 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Net Income fell 27.72% year-over-year to -$24.8 million; the TTM figure through Mar 2026 stood at -$60.5 million (up 22.77% YoY), while the FY2025 annual figure was -$160.1 million, down 1.18% from the prior year.
  • Net Income fell to -$24.8 million in Q1 2026 per OBIO's latest filing, from $6.4 million in the prior quarter.
  • Across five years, Net Income topped out at $6.4 million in Q4 2025 and bottomed at -$25.2 million in Q2 2024.
  • Historically, Net Income has averaged -$14.8 million across 5 years, with a median of -$16.1 million in 2024.
  • Annual changes were most pronounced in 2022 — Net Income plunged 8300.5% — and 2025, when it soared 139.71%.
  • Orchestra BioMed Holdings' Net Income stood at -$10.1 million in 2022, then fell by 23.72% to -$12.5 million in 2023, then decreased by 28.98% to -$16.1 million in 2024, then surged by 139.71% to $6.4 million in 2025, then tumbled by 487.22% to -$24.8 million in 2026.
  • Business Quant data shows OBIO's Net Income at -$24.8 million in Q1 2026, $6.4 million in Q4 2025, and -$20.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.10 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 1.30 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 482.00 Mn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -644.37 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 237.01 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 930.12
7 Royalty Pharma 33.72 Bn 35.84 Bn - 81.49 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 164.49 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -13.27 Mn
10 Orchestra BioMed Holdings 265.06 Mn 80.63 Mn 63,000.00 -25.29 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -25.29 Mn
Mar 31, 2026 -24.76 Mn
Dec 31, 2025 6.39 Mn
Sep 30, 2025 -20.54 Mn
Jun 30, 2025 -21.57 Mn
Mar 31, 2025 -19.38 Mn
Dec 31, 2024 -16.10 Mn
Sep 30, 2024 -17.62 Mn
Jun 30, 2024 -25.19 Mn
Mar 31, 2024 -15.80 Mn
Dec 31, 2023 -12.48 Mn
Sep 30, 2023 -22.02 Mn
Jun 30, 2023 -16.96 Mn
Mar 31, 2023 -11.90 Mn
Dec 31, 2022 -10.09 Mn
Sep 30, 2022 -10.45 Mn
Jun 30, 2022 -7.89 Mn
Mar 31, 2022 -5.36 Mn
Dec 31, 2021 -122,045.00
Sep 30, 2021 -124,445.00