Orchestra BioMed Holdings (OBIO) Free Cash Flow (2021 - 2026)

Orchestra BioMed Holdings (OBIO) reported Free Cash Flow of -$22.4 million for Q1 2026, down 33.62% year-over-year from -$33.7 million in Q1 2025, and down 1027.18% on a QoQ basis from -$2.0 million in Q4 2025.

Orchestra BioMed Holdings (OBIO) has 6 years of Free Cash Flow data on file, last reported at -$22.4 million in Q1 2026.

  • Quarterly Free Cash Flow fell 33.62% year-over-year to -$22.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$54.8 million (down 0.74% YoY) and the FY2025 annual result came in at -$49.1 million, up 3.37% from the prior year.
  • Free Cash Flow fell to -$22.4 million in Q1 2026 per OBIO's latest filing, from -$2.0 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$2.0 million in Q4 2025 and bottomed at -$22.4 million in Q1 2026.
  • The 5-year median for Free Cash Flow is -$11.0 million (2023), against an average of -$11.7 million.
  • The widest annual swing landed in 2022, when Free Cash Flow plunged 30411.53%; it then soared 85.63% in 2025.
  • Tracing OBIO's Free Cash Flow over 5 years: stood at -$8.8 million in 2022, then declined by 24.7% to -$11.0 million in 2023, then dropped by 25.79% to -$13.8 million in 2024, then soared by 85.63% to -$2.0 million in 2025, then tumbled by 1027.18% to -$22.4 million in 2026.
  • Per Business Quant, the three latest OBIO Free Cash Flow figures stand at -$22.4 million (Q1 2026), -$2.0 million (Q4 2025), and -$14.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -1.67 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.29 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 848.30 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 48.67 Mn
10 Orchestra BioMed Holdings 245.24 Mn 255.02 Mn 78,000.00 -22.35 Mn

Historic Data

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DateValue
Mar 31, 2026 -22.35 Mn
Mar 31, 2026 -22.35 Mn
Dec 31, 2025 -1.98 Mn
Dec 31, 2025 -1.98 Mn
Sep 30, 2025 -14.86 Mn
Sep 30, 2025 -14.86 Mn
Jun 30, 2025 -15.56 Mn
Jun 30, 2025 -15.56 Mn
Mar 31, 2025 -16.73 Mn
Mar 31, 2025 -16.73 Mn
Dec 31, 2024 -13.80 Mn
Dec 31, 2024 -13.80 Mn
Sep 30, 2024 -13.61 Mn
Sep 30, 2024 -13.61 Mn
Jun 30, 2024 -10.21 Mn
Jun 30, 2024 -10.21 Mn
Mar 31, 2024 -13.22 Mn
Mar 31, 2024 -13.22 Mn
Dec 31, 2023 -10.97 Mn
Dec 31, 2023 -10.97 Mn
Sep 30, 2023 -10.30 Mn
Sep 30, 2023 -10.30 Mn
Jun 30, 2023 -10.52 Mn
Jun 30, 2023 -10.52 Mn
Mar 31, 2023 -14.42 Mn
Mar 31, 2023 -14.42 Mn
Dec 31, 2022 -8.80 Mn
Dec 31, 2022 -8.80 Mn
Sep 30, 2022 -7.48 Mn
Sep 30, 2022 -7.48 Mn
Jun 30, 2022 -8.23 Mn
Jun 30, 2022 -8.23 Mn
Mar 31, 2022 -5.37 Mn
Mar 31, 2022 -5.37 Mn
Dec 31, 2021 -28,835.00
Dec 31, 2021 -28,835.00
Sep 30, 2021 -128,010.00
Sep 30, 2021 -128,010.00
Jun 30, 2021 -39,143.00
Jun 30, 2021 -39,143.00
Mar 31, 2021 -76,374.00
Mar 31, 2021 -76,374.00