Orchestra BioMed Holdings (OBIO) Free Cash Flow (2021 - 2026)

Orchestra BioMed Holdings (OBIO) posted quarterly Free Cash Flow of -$22.4 million for Q1 2026, down 33.62% year-over-year from -$33.7 million in Q1 2025, and down 848.32% quarter-over-quarter from -$2.4 million in Q4 2025.

Orchestra BioMed Holdings (OBIO) Free Cash Flow (2021 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has reported Free Cash Flow for 6 consecutive years, with -$22.4 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Free Cash Flow fell 33.62% year-over-year to -$22.4 million; the TTM figure through Mar 2026 stood at -$54.8 million (down 0.56% YoY), while the FY2025 annual figure was -$49.1 million, up 3.37% from the prior year.
  • Free Cash Flow slipped to -$22.4 million in Q1 2026 per OBIO's latest filing, from -$2.4 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$2.4 million in Q4 2025 and bottomed at -$22.4 million in Q1 2026.
  • Historically, Free Cash Flow has averaged -$11.7 million across 5 years, with a median of -$11.0 million in 2023.
  • Annual changes were most pronounced in 2022 — Free Cash Flow slumped 30411.53% — and 2025, when it jumped 82.73%.
  • Orchestra BioMed Holdings' Free Cash Flow stood at -$8.8 million in 2022, then decreased by 24.7% to -$11.0 million in 2023, then declined by 24.36% to -$13.6 million in 2024, then surged by 82.73% to -$2.4 million in 2025, then tumbled by 848.32% to -$22.4 million in 2026.
  • Business Quant data shows OBIO's Free Cash Flow at -$22.4 million in Q1 2026, -$2.4 million in Q4 2025, and -$14.5 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -389.61 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 437.80 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 477.44 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 292.04 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -95.09 Mn
10 Orchestra BioMed Holdings 265.06 Mn 80.63 Mn 63,000.00 -19.59 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -19.59 Mn
Jun 30, 2026 -19.59 Mn
Mar 31, 2026 -22.35 Mn
Mar 31, 2026 -22.35 Mn
Dec 31, 2025 -2.36 Mn
Dec 31, 2025 -2.36 Mn
Sep 30, 2025 -14.49 Mn
Sep 30, 2025 -14.49 Mn
Jun 30, 2025 -15.56 Mn
Jun 30, 2025 -15.56 Mn
Mar 31, 2025 -16.73 Mn
Mar 31, 2025 -16.73 Mn
Dec 31, 2024 -13.64 Mn
Dec 31, 2024 -13.64 Mn
Sep 30, 2024 -13.77 Mn
Sep 30, 2024 -13.77 Mn
Jun 30, 2024 -10.31 Mn
Jun 30, 2024 -10.31 Mn
Mar 31, 2024 -13.12 Mn
Mar 31, 2024 -13.12 Mn