Orchestra BioMed Holdings (OBIO) Change in Cash (2021 - 2026)

Orchestra BioMed Holdings' (OBIO) quarterly Change in Cash came in at -$6.3 million in Q1 2026, down 61.59% year-on-year from -$16.5 million in Q1 2025, and up 13.64% on a QoQ basis from -$7.3 million in Q4 2025.

Orchestra BioMed Holdings (OBIO) Change in Cash (2021 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has 6 years of Change in Cash data on file, last reported at -$6.3 million in Q1 2026.

  • On a quarterly basis, Change in Cash fell 61.59% year-over-year to -$6.3 million in Q1 2026; TTM through Mar 2026 was $10.0 million, a 301.35% increase from a year earlier, with the FY2025 full-year figure at $12.4 million, up 249.78% from the prior year.
  • Change in Cash for Q1 2026 stood at -$6.3 million, up from -$7.3 million in the prior quarter.
  • Over the last five years, Change in Cash for OBIO reached as high as $77.6 million in Q2 2022 and fell as low as -$77.2 million in Q4 2022.
  • Historically, Change in Cash has averaged $1.1 million across 5 years, with a median of -$1.1 million in 2023.
  • On a YoY basis, Change in Cash climbed as much as 198454.75% in 2022 and fell as far as 267668.34% in 2022.
  • Year by year, Change in Cash stood at -$77.2 million in 2022, then jumped by 114.87% to $11.5 million in 2023, then sank by 129.13% to -$3.3 million in 2024, then plunged by 118.96% to -$7.3 million in 2025, then gained by 13.64% to -$6.3 million in 2026.
  • Per Business Quant data, the three most recent Change in Cash figures were -$6.3 million in Q1 2026, -$7.3 million in Q4 2025, and $23.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -22.03 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 243.78 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.34 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 417.10 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -153.10 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - 57.19 Mn
10 Orchestra BioMed Holdings 228.31 Mn 143.68 Mn 78,000.00 -6.32 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -6.32 Mn
Dec 31, 2025 -7.32 Mn
Sep 30, 2025 23.26 Mn
Jun 30, 2025 401,000.00
Mar 31, 2025 -3.91 Mn
Dec 31, 2024 -3.34 Mn
Sep 30, 2024 1.89 Mn
Jun 30, 2024 389,000.00
Mar 31, 2024 -7.24 Mn
Dec 31, 2023 11.48 Mn
Sep 30, 2023 2.67 Mn
Jun 30, 2023 -2.29 Mn
Mar 31, 2023 -1.09 Mn
Dec 31, 2022 -77.21 Mn
Sep 30, 2022 -9.98 Mn
Jun 30, 2022 77.64 Mn
Mar 31, 2022 19.39 Mn
Dec 31, 2021 -28,835.00
Sep 30, 2021 -128,010.00
Jun 30, 2021 -39,143.00