Mirum Pharmaceuticals (MIRM) Net Margin (2021 - 2026)

Mirum Pharmaceuticals' (MIRM) quarterly Net Margin came in at 494.21% in Q1 2026, down 48106.0% year-on-year from N/an in Q1 2025, and down 12745.36% quarter-over-quarter from 3.85% in Q4 2025.

Mirum Pharmaceuticals (MIRM) Net Margin (2021 - 2026) Analysis & Trends

Mirum Pharmaceuticals' Net Margin history runs 6 years deep, the most recent figure standing at 494.21% for Q1 2026.

  • On a quarterly basis, Net Margin fell 48106.0% year-over-year to 494.21% in Q1 2026; TTM through Mar 2026 was 140.24%, a 11985.0% decrease from a year earlier, with the FY2025 full-year figure at 4.48%, up 2162.0% from the prior year.
  • Net Margin eased to 494.21% in Q1 2026 per MIRM's latest filing, from 3.85% in the prior quarter.
  • Across five years, Net Margin topped out at 2.18% in Q3 2025 and bottomed at 494.21% in Q1 2026.
  • The 5-year median for Net Margin is 49.42% (2023), against an average of 104.33%.
  • Biggest YoY gain for Net Margin was 75203 bps in 2022; the steepest drop was 195592 bps in 2022.
  • Year by year, Net Margin stood at 130.55% in 2022, then surged by 61 bps to 51.27% in 2023, then soared by 53 bps to 23.93% in 2024, then jumped by 84 bps to 3.85% in 2025, then plunged by 12745 bps to 494.21% in 2026.
  • Per Business Quant, the three latest MIRM Net Margin figures stand at 494.21% (Q1 2026), 3.85% (Q4 2025), and 2.18% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 15.02%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 20.17%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 30.33%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Mirum Pharmaceuticals 6.73 Bn 6.34 Bn 131.08 Mn -494.21%

Historic Data

Download Data
DateValue
Mar 31, 2026 -494.21%
Dec 31, 2025 -3.85%
Sep 30, 2025 2.18%
Jun 30, 2025 -4.59%
Mar 31, 2025 -13.15%
Dec 31, 2024 -23.93%
Sep 30, 2024 -15.75%
Jun 30, 2024 -31.64%
Mar 31, 2024 -36.52%
Dec 31, 2023 -51.27%
Sep 30, 2023 -49.42%
Jun 30, 2023 -197.45%
Mar 31, 2023 -95.35%
Dec 31, 2022 -130.55%
Sep 30, 2022 -190.13%
Jun 30, 2022 -153.98%
Mar 31, 2022 -283.94%
Dec 31, 2021 1,825.37%
Sep 30, 2021 -942.16%
Jun 30, 2021 -399.04%