Mirum Pharmaceuticals (MIRM) Net Margin (2021 - 2026)
Mirum Pharmaceuticals' Net Margin came in at -38.14% for Q2 2026, down 33.56 percentage points from -4.59% a year earlier but up 456.07 percentage points from the prior quarter.
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Analysis
Mirum Pharmaceuticals (MIRM) Net Margin (2021 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Mirum Pharmaceuticals reported Net Margin of -139.18%, down 125.53 percentage points year-over-year; for FY2025, it was -4.48%, up 21.62 percentage points from FY2024.
- Net Margin has increased in each of the last four years, with a four-year change of +434.37 percentage points (FY2021 to FY2025).
- Going back by year, Net Margin was -26.10% in FY2024 (+61.58 pp), -87.68% in FY2023 (+88.37 pp), -176.05% in FY2022 (+262.81 pp) and -438.85% in FY2021.
- The five-year range for quarterly Net Margin is -942.16% (Q3 2021) to 1833.84% (Q4 2021).
- Year-over-year, Net Margin increased in six of the last eight quarters, with an average year-over-year change of -45.65 percentage points.
- The fastest year-over-year change in Net Margin over five years came in Q3 2022 (a gain of 752.03 percentage points), and the weakest in Q4 2022 (a drop of 1964.39 percentage points).
- Business Quant data shows MIRM's Net Margin at -494.21% (Q1 2026), -3.85% (Q4 2025) and 2.18% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Mirum Pharmaceuticals | 5.70 Bn | 4.11 Bn | 145.90 Mn | -38.14% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -38.14% |
| Mar 31, 2026 | -494.21% |
| Dec 31, 2025 | -3.85% |
| Sep 30, 2025 | 2.18% |
| Jun 30, 2025 | -4.59% |
| Mar 31, 2025 | -13.15% |
| Dec 31, 2024 | -23.93% |
| Sep 30, 2024 | -15.75% |
| Jun 30, 2024 | -31.64% |
| Mar 31, 2024 | -36.52% |
| Dec 31, 2023 | -51.27% |
| Sep 30, 2023 | -49.42% |
| Jun 30, 2023 | -197.45% |
| Mar 31, 2023 | -95.35% |
| Dec 31, 2022 | -130.55% |
| Sep 30, 2022 | -190.13% |
| Jun 30, 2022 | -155.12% |
| Mar 31, 2022 | -283.94% |
| Dec 31, 2021 | 1,833.84% |
| Sep 30, 2021 | -942.16% |
API Access
Mirum Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=MIRM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "MIRM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=MIRM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();