Mirum Pharmaceuticals (MIRM) Net Margin (2021 - 2026)

Mirum Pharmaceuticals (MIRM) posted quarterly Net Margin of 494.21% for Q1 2026, down 48106.0% year-over-year from N/an in Q1 2025, and down 12745.36% quarter-over-quarter from 3.85% in Q4 2025.

Mirum Pharmaceuticals (MIRM) Net Margin (2021 - 2026) Analysis & Trends

Mirum Pharmaceuticals' Net Margin history runs 6 years deep, the most recent figure standing at 494.21% for Q1 2026.

  • In Q1 2026, Net Margin fell 48106.0% year-over-year to 494.21%; the TTM figure through Mar 2026 stood at 140.24% (down 11985.0% YoY), while the FY2025 annual figure was 4.48%, up 2162.0% from the prior year.
  • Net Margin for Q1 2026 stood at 494.21%, down from 3.85% in the prior quarter.
  • The five-year high for Net Margin was 2.18% in Q3 2025, with the low at 494.21% in Q1 2026.
  • The 5-year median for Net Margin is 49.42% (2023), against an average of 104.33%.
  • Peak annual rise in Net Margin reached 75203 bps in 2022, while the deepest fall reached 195592 bps in 2022.
  • Mirum Pharmaceuticals' Net Margin stood at 130.55% in 2022, then jumped by 61 bps to 51.27% in 2023, then surged by 53 bps to 23.93% in 2024, then soared by 84 bps to 3.85% in 2025, then sank by 12745 bps to 494.21% in 2026.
  • Business Quant data shows MIRM's Net Margin at 494.21% in Q1 2026, 3.85% in Q4 2025, and 2.18% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 32.99%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 30.23%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 30.33%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.90%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 30.98%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 12.74%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -3.12%
10 Mirum Pharmaceuticals 6.52 Bn 6.08 Bn 145.90 Mn -38.14%

Historic Data

Download Data
DateValue
Jun 30, 2026 -38.14%
Mar 31, 2026 -494.21%
Dec 31, 2025 -3.85%
Sep 30, 2025 2.18%
Jun 30, 2025 -4.59%
Mar 31, 2025 -13.15%
Dec 31, 2024 -23.93%
Sep 30, 2024 -15.75%
Jun 30, 2024 -31.64%
Mar 31, 2024 -36.52%
Dec 31, 2023 -51.27%
Sep 30, 2023 -49.42%
Jun 30, 2023 -197.45%
Mar 31, 2023 -95.35%
Dec 31, 2022 -130.55%
Sep 30, 2022 -190.13%
Jun 30, 2022 -153.98%
Mar 31, 2022 -283.94%
Dec 31, 2021 1,825.37%
Sep 30, 2021 -942.16%