Macrogenics (MGNX) Gross Margin (2020 - 2025)

Macrogenics' (MGNX) quarterly Gross Margin came in at 100.0% in Q4 2025, up 58.0% year-on-year from 63.29% in Q4 2024, and little changed on a QoQ basis from 100.0% in Q3 2025.

Macrogenics (MGNX) Gross Margin (2020 - 2025) Analysis & Trends

Macrogenics (MGNX) has 6 years of Gross Margin data on file, last reported at 100.0% in Q4 2025.

  • On a quarterly basis, Gross Margin rose 58.0% year-over-year to 100.0% in Q4 2025; TTM through Dec 2025 was 100.0%, a 50.0% increase from a year earlier, with the FY2025 full-year figure at 100.0%, up 56.0% from the prior year.
  • Gross Margin for Q4 2025 stood at 100.0%, roughly flat from 100.0% in the prior quarter.
  • Over the last five years, Gross Margin for MGNX reached as high as 100.0% in Q1 2025 and fell as low as 89.37% in Q3 2021.
  • Historically, Gross Margin has averaged 98.2% across 5 years, with a median of 99.48% in 2023.
  • Across the five-year window, Gross Margin tumbled 1063 bps in 2021 and jumped 654 bps in 2022, its largest moves.
  • Year by year, Gross Margin stood at 93.31% in 2021, then gained by 7 bps to 99.84% in 2022, then slipped by 1 bps to 98.48% in 2023, then advanced by 1 bps to 99.42% in 2024, then climbed by 1 bps to 100.0% in 2025.
  • Per Business Quant data, the three most recent Gross Margin figures were 100.0% in Q4 2025, 100.0% in Q3 2025, and 100.0% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 88.95%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 91.79%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 90.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Macrogenics 254.43 Mn 187.92 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 100.00%
Sep 30, 2025 100.00%
Jun 30, 2025 100.00%
Mar 31, 2025 100.00%
Dec 31, 2024 99.42%
Sep 30, 2024 99.85%
Jun 30, 2024 98.37%
Mar 31, 2024 97.03%
Dec 31, 2023 98.48%
Sep 30, 2023 99.18%
Jun 30, 2023 98.04%
Mar 31, 2023 99.54%
Dec 31, 2022 99.84%
Sep 30, 2022 92.79%
Jun 30, 2022 99.31%
Mar 31, 2022 99.57%
Dec 31, 2021 93.31%
Sep 30, 2021 89.37%
Jun 30, 2021 99.93%
Mar 31, 2021 99.90%