Macrogenics (MGNX) Gross Margin (2020 - 2026)
Macrogenics (MGNX) posted quarterly Gross Margin of 100.0% for Q4 2025, up 58.0% year-over-year from 63.29% in Q4 2024, and little changed quarter-over-quarter from 100.0% in Q3 2025.
Analysis
Macrogenics (MGNX) Gross Margin (2020 - 2026) Analysis & Trends
Macrogenics (MGNX) has reported Gross Margin for 6 consecutive years, with 100.0% the latest figure, recorded in Q4 2025.
- In Q4 2025, Gross Margin rose 58.0% year-over-year to 100.0%; the TTM figure through Dec 2025 stood at 100.0% (up 50.0% YoY), while the FY2025 annual figure was 100.0%, up 56.0% from the prior year.
- Gross Margin was little changed at 100.0% in Q4 2025 per MGNX's latest filing, from 100.0% in the prior quarter.
- Across five years, Gross Margin topped out at 100.0% in Q1 2025 and bottomed at 89.37% in Q3 2021.
- Historically, Gross Margin has averaged 98.2% across 5 years, with a median of 99.48% in 2023.
- Annual changes were most pronounced in 2021 — Gross Margin sank 1063 bps — and 2022, when it soared 654 bps.
- Macrogenics' Gross Margin stood at 93.31% in 2021, then increased by 7 bps to 99.84% in 2022, then retreated by 1 bps to 98.48% in 2023, then rose by 1 bps to 99.42% in 2024, then gained by 1 bps to 100.0% in 2025.
- Business Quant data shows MGNX's Gross Margin at 100.0% in Q4 2025, 100.0% in Q3 2025, and 100.0% in Q2 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 90.43% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | 35.86% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 89.76% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 76.90% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | - |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | 84.20% |
| 10 | Macrogenics | 284.90 Mn | 171.00 Mn | - | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | 54.13% |
| Dec 31, 2025 | 75.47% |
| Sep 30, 2025 | 84.09% |
| Jun 30, 2025 | -29.65% |
| Mar 31, 2025 | 59.07% |
| Dec 31, 2024 | 86.86% |
| Sep 30, 2024 | 98.46% |
| Jun 30, 2024 | 75.48% |
| Mar 31, 2024 | 79.72% |
| Dec 31, 2023 | 100.00% |
| Sep 30, 2023 | 68.51% |
| Jun 30, 2023 | 93.00% |
| Mar 31, 2023 | 86.08% |
| Dec 31, 2022 | 98.91% |
| Sep 30, 2022 | 92.79% |
| Jun 30, 2022 | 91.46% |
| Mar 31, 2022 | 99.57% |
| Dec 31, 2021 | 93.31% |
| Sep 30, 2021 | 89.37% |
| Jun 30, 2021 | 99.93% |