Macrogenics (MGNX) Gross Margin (2020 - 2025)

Macrogenics (MGNX) reported Gross Margin of 100.0% for Q4 2025, up 58.0% year-over-year from 63.29% in Q4 2024, and little changed quarter-over-quarter from 100.0% in Q3 2025.

Macrogenics (MGNX) Gross Margin (2020 - 2025) Analysis & Trends

Macrogenics (MGNX) has 6 years of Gross Margin data on file, last reported at 100.0% in Q4 2025.

  • Gross Margin for Q4 2025 came in at 100.0%, up 58.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 100.0% (up 52.0% YoY), and the FY2025 annual result was 100.0%, up 56.0% from the prior year.
  • Gross Margin was little changed at 100.0% in Q4 2025 per MGNX's latest filing, from 100.0% in the prior quarter.
  • Over five years, Gross Margin peaked at 100.0% in Q1 2025 and troughed at 89.37% in Q3 2021.
  • A 5-year average of 98.01% and a median of 99.48% in 2023 frame the typical range for Gross Margin.
  • The sharpest annual moves came in 2021 and 2022: Gross Margin sank 1063 bps in 2021, then soared 654 bps in 2022.
  • A 5-year view of Gross Margin shows it stood at 93.31% in 2021, then grew by 7 bps to 99.84% in 2022, then fell by 1 bps to 98.48% in 2023, then increased by 1 bps to 99.42% in 2024, then rose by 1 bps to 100.0% in 2025.
  • Business Quant data shows MGNX's Gross Margin at 100.0% in Q4 2025, 100.0% in Q3 2025, and 100.0% in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Macrogenics 260.14 Mn 193.63 Mn - -

Historic Data

Download Data
DateValue
Dec 31, 2025 100.00%
Sep 30, 2025 100.00%
Jun 30, 2025 100.00%
Mar 31, 2025 100.00%
Dec 31, 2024 99.42%
Sep 30, 2024 99.85%
Jun 30, 2024 94.67%
Mar 31, 2024 97.03%
Dec 31, 2023 98.48%
Sep 30, 2023 99.18%
Jun 30, 2023 98.04%
Mar 31, 2023 99.54%
Dec 31, 2022 99.84%
Sep 30, 2022 92.79%
Jun 30, 2022 99.31%
Mar 31, 2022 99.57%
Dec 31, 2021 93.31%
Sep 30, 2021 89.37%
Jun 30, 2021 99.93%
Mar 31, 2021 99.90%