Macrogenics (MGNX) Gross Margin (2020 - 2025)
Macrogenics (MGNX) reported Gross Margin of 100.0% for Q4 2025, up 58.0% year-over-year from 63.29% in Q4 2024, and little changed quarter-over-quarter from 100.0% in Q3 2025.
Macrogenics (MGNX) Gross Margin (2020 - 2025) Analysis & Trends
Macrogenics (MGNX) has 6 years of Gross Margin data on file, last reported at 100.0% in Q4 2025.
- Gross Margin for Q4 2025 came in at 100.0%, up 58.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 100.0% (up 52.0% YoY), and the FY2025 annual result was 100.0%, up 56.0% from the prior year.
- Gross Margin was little changed at 100.0% in Q4 2025 per MGNX's latest filing, from 100.0% in the prior quarter.
- Over five years, Gross Margin peaked at 100.0% in Q1 2025 and troughed at 89.37% in Q3 2021.
- A 5-year average of 98.01% and a median of 99.48% in 2023 frame the typical range for Gross Margin.
- The sharpest annual moves came in 2021 and 2022: Gross Margin sank 1063 bps in 2021, then soared 654 bps in 2022.
- A 5-year view of Gross Margin shows it stood at 93.31% in 2021, then grew by 7 bps to 99.84% in 2022, then fell by 1 bps to 98.48% in 2023, then increased by 1 bps to 99.42% in 2024, then rose by 1 bps to 100.0% in 2025.
- Business Quant data shows MGNX's Gross Margin at 100.0% in Q4 2025, 100.0% in Q3 2025, and 100.0% in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Macrogenics | 260.14 Mn | 193.63 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 100.00% |
| Sep 30, 2025 | 100.00% |
| Jun 30, 2025 | 100.00% |
| Mar 31, 2025 | 100.00% |
| Dec 31, 2024 | 99.42% |
| Sep 30, 2024 | 99.85% |
| Jun 30, 2024 | 94.67% |
| Mar 31, 2024 | 97.03% |
| Dec 31, 2023 | 98.48% |
| Sep 30, 2023 | 99.18% |
| Jun 30, 2023 | 98.04% |
| Mar 31, 2023 | 99.54% |
| Dec 31, 2022 | 99.84% |
| Sep 30, 2022 | 92.79% |
| Jun 30, 2022 | 99.31% |
| Mar 31, 2022 | 99.57% |
| Dec 31, 2021 | 93.31% |
| Sep 30, 2021 | 89.37% |
| Jun 30, 2021 | 99.93% |
| Mar 31, 2021 | 99.90% |