Macrogenics (MGNX) Gross Margin (2020 - 2025)
Macrogenics' (MGNX) quarterly Gross Margin came in at 100.0% in Q4 2025, up 58.0% year-on-year from 63.29% in Q4 2024, and little changed on a QoQ basis from 100.0% in Q3 2025.
Macrogenics (MGNX) Gross Margin (2020 - 2025) Analysis & Trends
Macrogenics (MGNX) has 6 years of Gross Margin data on file, last reported at 100.0% in Q4 2025.
- On a quarterly basis, Gross Margin rose 58.0% year-over-year to 100.0% in Q4 2025; TTM through Dec 2025 was 100.0%, a 50.0% increase from a year earlier, with the FY2025 full-year figure at 100.0%, up 56.0% from the prior year.
- Gross Margin for Q4 2025 stood at 100.0%, roughly flat from 100.0% in the prior quarter.
- Over the last five years, Gross Margin for MGNX reached as high as 100.0% in Q1 2025 and fell as low as 89.37% in Q3 2021.
- Historically, Gross Margin has averaged 98.2% across 5 years, with a median of 99.48% in 2023.
- Across the five-year window, Gross Margin tumbled 1063 bps in 2021 and jumped 654 bps in 2022, its largest moves.
- Year by year, Gross Margin stood at 93.31% in 2021, then gained by 7 bps to 99.84% in 2022, then slipped by 1 bps to 98.48% in 2023, then advanced by 1 bps to 99.42% in 2024, then climbed by 1 bps to 100.0% in 2025.
- Per Business Quant data, the three most recent Gross Margin figures were 100.0% in Q4 2025, 100.0% in Q3 2025, and 100.0% in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 88.95% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 90.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Macrogenics | 254.43 Mn | 187.92 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 100.00% |
| Sep 30, 2025 | 100.00% |
| Jun 30, 2025 | 100.00% |
| Mar 31, 2025 | 100.00% |
| Dec 31, 2024 | 99.42% |
| Sep 30, 2024 | 99.85% |
| Jun 30, 2024 | 98.37% |
| Mar 31, 2024 | 97.03% |
| Dec 31, 2023 | 98.48% |
| Sep 30, 2023 | 99.18% |
| Jun 30, 2023 | 98.04% |
| Mar 31, 2023 | 99.54% |
| Dec 31, 2022 | 99.84% |
| Sep 30, 2022 | 92.79% |
| Jun 30, 2022 | 99.31% |
| Mar 31, 2022 | 99.57% |
| Dec 31, 2021 | 93.31% |
| Sep 30, 2021 | 89.37% |
| Jun 30, 2021 | 99.93% |
| Mar 31, 2021 | 99.90% |