Legend Biotech (LEGN) Gross Margin (2019 - 2025)
Legend Biotech (LEGN) posted Gross Margin of 79.04% for Q4 2025, down 2.04% on a QoQ basis from 80.68% in Q3 2025, and up 526.0% year-over-year from 12.63% in Q4 2024.
Legend Biotech (LEGN) has 7 years of Gross Margin data on file, last reported at 79.04% in Q4 2025.
- In Q4 2025, Gross Margin rose 526.0% year-over-year to 79.04%; the TTM figure through Dec 2025 stood at 79.99% (up 350.0% YoY), while the FY2025 annual figure was 80.0%, up 351.0% from the prior year.
- Gross Margin eased to 79.04% in Q4 2025, from 80.68% in the prior quarter.
- Across five years, Gross Margin topped out at 100.0% in Q4 2023 and bottomed at 97963.15% in Q1 2021.
- A 5-year average of 4855.39% and a median of 71.57% in 2023 frame the typical range for Gross Margin.
- Annual changes were most pronounced in 2021 — Gross Margin sank 9800646 bps — and 2022, when it soared 9802058 bps.
- Year by year, Gross Margin stood at 35.43% in 2021, then jumped by 118 bps to 6.55% in 2022, then surged by 1427 bps to 100.0% in 2023, then decreased by 26 bps to 73.78% in 2024, then rose by 7 bps to 79.04% in 2025.
- The last three Gross Margin figures came in at 79.04% (Q4 2025), 80.68% (Q3 2025), and 81.16% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | 79.04% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 86.85% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 91.79% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 82.22% |
| 10 | Revolution Medicines | 32.39 Bn | 32.39 Bn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 79.04% |
| Sep 30, 2025 | 80.68% |
| Jun 30, 2025 | 81.16% |
| Mar 31, 2025 | 79.00% |
| Dec 31, 2024 | 73.78% |
| Sep 30, 2024 | 72.37% |
| Jun 30, 2024 | 83.88% |
| Mar 31, 2024 | 74.23% |
| Dec 31, 2023 | 100.00% |
| Sep 30, 2023 | 78.03% |
| Jun 30, 2023 | 70.78% |
| Mar 31, 2023 | 50.59% |
| Dec 31, 2022 | 6.55% |
| Sep 30, 2022 | 31.10% |
| Jun 30, 2022 | -129.22% |
| Mar 31, 2022 | 57.43% |
| Dec 31, 2021 | -35.43% |
| Sep 30, 2021 | -15.70% |
| Jun 30, 2021 | 17.06% |
| Mar 31, 2021 | -97,963.15% |
| Dec 31, 2020 | 40.71% |
| Sep 30, 2020 | 20.94% |
| Jun 30, 2020 | 17.61% |
| Mar 31, 2020 | 43.31% |
| Dec 31, 2019 | 31.24% |
| Sep 30, 2019 | 74.77% |
| Jun 30, 2019 | 50.13% |