Krystal Biotech (KRYS) Operating Income (2016 - 2026)
Krystal Biotech's (KRYS) quarterly Operating Income came in at $53.7 million in Q1 2026, up 48.1% year-on-year from $36.3 million in Q1 2025, and up 21.28% quarter-over-quarter from $44.3 million in Q4 2025.
Krystal Biotech (KRYS) Operating Income (2016 - 2026) Analysis & Trends
Krystal Biotech has disclosed Operating Income across 11 years of filings, most recently posting $53.7 million for Q1 2026.
- Operating Income for Q1 2026 came in at $53.7 million, up 48.1% year-over-year; the trailing twelve-month figure through Mar 2026 was $178.6 million (up 64.4% YoY), and the FY2025 annual result was $161.3 million, up 145.32% from the prior year.
- Operating Income came in at $53.7 million for Q1 2026 at Krystal Biotech, up from $44.3 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $53.7 million in Q1 2026 to a low of -$50.2 million in Q1 2022.
- The 5-year median for Operating Income is $3.2 million (2023), against an average of $1.5 million.
- Across the five-year window, Operating Income plunged 249.91% in 2022 and surged 1173.86% in 2024, its largest moves.
- Krystal Biotech's Operating Income stood at -$34.8 million in 2022, then jumped by 109.34% to $3.2 million in 2023, then soared by 1173.86% to $41.4 million in 2024, then increased by 7.0% to $44.3 million in 2025, then climbed by 21.28% to $53.7 million in 2026.
- The last three Operating Income figures came in at $53.7 million (Q1 2026), $44.3 million (Q4 2025), and $41.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Krystal Biotech | 10.23 Bn | 9.41 Bn | 110.03 Mn | 53.69 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 53.69 Mn |
| Dec 31, 2025 | 44.27 Mn |
| Sep 30, 2025 | 41.37 Mn |
| Jun 30, 2025 | 39.31 Mn |
| Mar 31, 2025 | 36.25 Mn |
| Dec 31, 2024 | 41.38 Mn |
| Sep 30, 2024 | 22.47 Mn |
| Jun 30, 2024 | 8.57 Mn |
| Mar 31, 2024 | -6.68 Mn |
| Dec 31, 2023 | 3.25 Mn |
| Sep 30, 2023 | -25.99 Mn |
| Jun 30, 2023 | -38.05 Mn |
| Mar 31, 2023 | -48.82 Mn |
| Dec 31, 2022 | -34.77 Mn |
| Sep 30, 2022 | -31.45 Mn |
| Jun 30, 2022 | -28.75 Mn |
| Mar 31, 2022 | -50.22 Mn |
| Dec 31, 2021 | -21.88 Mn |
| Sep 30, 2021 | -15.65 Mn |
| Jun 30, 2021 | -16.39 Mn |