Krystal Biotech (KRYS) Net Margin (2023 - 2026)

Krystal Biotech (KRYS) reported Net Margin of 48.06% for Q1 2026, up 754.0% on a YoY basis from 5.63% in Q1 2025, and little changed sequentially from 47.98% in Q4 2025.

Krystal Biotech (KRYS) Net Margin (2023 - 2026) Analysis & Trends

Krystal Biotech (KRYS) has 4 years of Net Margin data on file, last reported at 48.06% in Q1 2026.

  • For the quarter ending Q1 2026, Net Margin rose 754.0% year-over-year to 48.06%; the trailing twelve-month figure through Mar 2026 stood at 53.93% (up 1676.0% YoY), and the FY2025 full-year result was 52.64%, up 2195.0% from the prior year.
  • Net Margin was little changed at 48.06% in Q1 2026, from 47.98% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 943.75% in Q3 2023 to a low of 2.06% in Q1 2024.
  • A 4-year average of 120.78% and a median of 40.52% in 2025 frame the typical range for Net Margin.
  • Across the five-year window, Net Margin tumbled 91134 bps in 2024 and surged 4874 bps in 2025, its largest moves.
  • Tracing KRYS's Net Margin over 4 years: stood at 20.63% in 2023, then soared by 142 bps to 49.9% in 2024, then fell by 4 bps to 47.98% in 2025, then grew by 0 bps to 48.06% in 2026.
  • Business Quant data shows KRYS's Net Margin at 48.06% in Q1 2026, 47.98% in Q4 2025, and 81.15% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 15.02%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 20.17%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 28.20%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Krystal Biotech 9.84 Bn 9.02 Bn 110.08 Mn 48.06%

Historic Data

Download Data
DateValue
Mar 31, 2026 48.06%
Dec 31, 2025 47.98%
Sep 30, 2025 81.15%
Jun 30, 2025 39.96%
Mar 31, 2025 40.52%
Dec 31, 2024 49.90%
Sep 30, 2024 32.41%
Jun 30, 2024 22.15%
Mar 31, 2024 2.06%
Dec 31, 2023 20.63%
Sep 30, 2023 943.75%