Krystal Biotech (KRYS) Net Margin (2023 - 2026)

Krystal Biotech's (KRYS) quarterly Net Margin came in at 48.07% in Q1 2026, up 755.0% year-on-year from 5.62% in Q1 2025, and little changed quarter-over-quarter from 47.99% in Q4 2025.

Krystal Biotech (KRYS) Net Margin (2023 - 2026) Analysis & Trends

Krystal Biotech has disclosed Net Margin across 4 years of filings, most recently posting 48.07% for Q1 2026.

  • Net Margin for Q1 2026 came in at 48.07%, up 755.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 53.94% (up 1675.0% YoY), and the FY2025 annual result was 52.64%, up 2195.0% from the prior year.
  • Net Margin came in at 48.07% for Q1 2026 at Krystal Biotech, roughly flat from 47.99% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 943.75% in Q3 2023 to a low of 2.06% in Q1 2024.
  • The 4-year median for Net Margin is 40.52% (2025), against an average of 120.79%.
  • Across the five-year window, Net Margin plunged 91133 bps in 2024 and soared 4873 bps in 2025, its largest moves.
  • Krystal Biotech's Net Margin stood at 20.63% in 2023, then surged by 142 bps to 49.95% in 2024, then fell by 4 bps to 47.99% in 2025, then rose by 0 bps to 48.07% in 2026.
  • The last three Net Margin figures came in at 48.07% (Q1 2026), 47.99% (Q4 2025), and 81.15% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.82%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 34.53%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn 48.07%

Historic Data

Download Data
DateValue
Mar 31, 2026 48.07%
Dec 31, 2025 47.99%
Sep 30, 2025 81.15%
Jun 30, 2025 39.97%
Mar 31, 2025 40.52%
Dec 31, 2024 49.95%
Sep 30, 2024 32.42%
Jun 30, 2024 22.15%
Mar 31, 2024 2.06%
Dec 31, 2023 20.63%
Sep 30, 2023 943.75%