Krystal Biotech (KRYS) Net Margin (2023 - 2026)
Krystal Biotech (KRYS) reported Net Margin of 48.06% for Q1 2026, up 754.0% on a YoY basis from 5.63% in Q1 2025, and little changed sequentially from 47.98% in Q4 2025.
Krystal Biotech (KRYS) Net Margin (2023 - 2026) Analysis & Trends
Krystal Biotech (KRYS) has 4 years of Net Margin data on file, last reported at 48.06% in Q1 2026.
- For the quarter ending Q1 2026, Net Margin rose 754.0% year-over-year to 48.06%; the trailing twelve-month figure through Mar 2026 stood at 53.93% (up 1676.0% YoY), and the FY2025 full-year result was 52.64%, up 2195.0% from the prior year.
- Net Margin was little changed at 48.06% in Q1 2026, from 47.98% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 943.75% in Q3 2023 to a low of 2.06% in Q1 2024.
- A 4-year average of 120.78% and a median of 40.52% in 2025 frame the typical range for Net Margin.
- Across the five-year window, Net Margin tumbled 91134 bps in 2024 and surged 4874 bps in 2025, its largest moves.
- Tracing KRYS's Net Margin over 4 years: stood at 20.63% in 2023, then soared by 142 bps to 49.9% in 2024, then fell by 4 bps to 47.98% in 2025, then grew by 0 bps to 48.06% in 2026.
- Business Quant data shows KRYS's Net Margin at 48.06% in Q1 2026, 47.98% in Q4 2025, and 81.15% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | - |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 15.02% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 28.20% |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | - |
| 10 | Krystal Biotech | 9.84 Bn | 9.02 Bn | 110.08 Mn | 48.06% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.06% |
| Dec 31, 2025 | 47.98% |
| Sep 30, 2025 | 81.15% |
| Jun 30, 2025 | 39.96% |
| Mar 31, 2025 | 40.52% |
| Dec 31, 2024 | 49.90% |
| Sep 30, 2024 | 32.41% |
| Jun 30, 2024 | 22.15% |
| Mar 31, 2024 | 2.06% |
| Dec 31, 2023 | 20.63% |
| Sep 30, 2023 | 943.75% |