Krystal Biotech (KRYS) Net Margin (2023 - 2026)
Krystal Biotech recorded quarterly Net Margin of 48.07% in Q1 2026, little changed quarter-over-quarter from 47.99% in Q4 2025, and up 755.0% year-over-year from 5.62% in Q1 2025.
Krystal Biotech's Net Margin history runs 4 years deep, the most recent figure standing at 48.07% for Q1 2026.
- In Q1 2026, Net Margin rose 755.0% year-over-year to 48.07%; the TTM figure through Mar 2026 stood at 53.94% (up 1675.0% YoY), while the FY2025 annual figure was 52.64%, up 2195.0% from the prior year.
- Net Margin came in at 48.07% for Q1 2026 at Krystal Biotech, roughly flat from 47.99% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 943.75% in Q3 2023 to a low of 2.06% in Q1 2024.
- A 4-year average of 120.79% and a median of 40.52% in 2025 frame the typical range for Net Margin.
- Across the five-year window, Net Margin tumbled 91133 bps in 2024 and jumped 4873 bps in 2025, its largest moves.
- Krystal Biotech's Net Margin stood at 20.63% in 2023, then soared by 142 bps to 49.95% in 2024, then retreated by 4 bps to 47.99% in 2025, then gained by 0 bps to 48.07% in 2026.
- According to Business Quant data, Net Margin over the past three periods registered 48.07%, 47.99%, and 81.15% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | 0.82% |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 34.53% |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 20.17% |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 17.65% |
| 10 | Krystal Biotech | 9.05 Bn | 8.23 Bn | 110.03 Mn | 48.07% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.07% |
| Dec 31, 2025 | 47.99% |
| Sep 30, 2025 | 81.15% |
| Jun 30, 2025 | 39.97% |
| Mar 31, 2025 | 40.52% |
| Dec 31, 2024 | 49.95% |
| Sep 30, 2024 | 32.42% |
| Jun 30, 2024 | 22.15% |
| Mar 31, 2024 | 2.06% |
| Dec 31, 2023 | 20.63% |
| Sep 30, 2023 | 943.75% |