Growth Metrics

Krystal Biotech (KRYS) Net Margin (2021 - 2025)

Krystal Biotech's Net Margin history spans 4 years, with the latest figure at 47.99% for Q4 2025.

  • For Q4 2025, Net Margin fell 192.0% year-over-year to 47.99%; the TTM value through Dec 2025 reached 52.64%, up 2195.0%, while the annual FY2025 figure was 52.64%, 2195.0% up from the prior year.
  • Net Margin for Q4 2025 was 47.99% at Krystal Biotech, down from 81.16% in the prior quarter.
  • Across five years, Net Margin topped out at 1059.79% in Q1 2021 and bottomed at 2.06% in Q1 2024.
  • The 4-year median for Net Margin is 40.51% (2025), against an average of 212.75%.
  • The largest annual shift saw Net Margin crashed -91133bps in 2024 before it soared 4874bps in 2025.
  • A 4-year view of Net Margin shows it stood at 1059.79% in 2021, then crashed by -98bps to 20.63% in 2023, then skyrocketed by 142bps to 49.91% in 2024, then dropped by -4bps to 47.99% in 2025.
  • Per Business Quant, the three most recent readings for KRYS's Net Margin are 47.99% (Q4 2025), 81.16% (Q3 2025), and 39.93% (Q2 2025).