Krystal Biotech (KRYS) Net Margin (2023 - 2026)
Krystal Biotech's (KRYS) quarterly Net Margin came in at 48.07% in Q1 2026, up 755.0% year-on-year from 5.62% in Q1 2025, and little changed quarter-over-quarter from 47.99% in Q4 2025.
Krystal Biotech (KRYS) Net Margin (2023 - 2026) Analysis & Trends
Krystal Biotech has disclosed Net Margin across 4 years of filings, most recently posting 48.07% for Q1 2026.
- Net Margin for Q1 2026 came in at 48.07%, up 755.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 53.94% (up 1675.0% YoY), and the FY2025 annual result was 52.64%, up 2195.0% from the prior year.
- Net Margin came in at 48.07% for Q1 2026 at Krystal Biotech, roughly flat from 47.99% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 943.75% in Q3 2023 to a low of 2.06% in Q1 2024.
- The 4-year median for Net Margin is 40.52% (2025), against an average of 120.79%.
- Across the five-year window, Net Margin plunged 91133 bps in 2024 and soared 4873 bps in 2025, its largest moves.
- Krystal Biotech's Net Margin stood at 20.63% in 2023, then surged by 142 bps to 49.95% in 2024, then fell by 4 bps to 47.99% in 2025, then rose by 0 bps to 48.07% in 2026.
- The last three Net Margin figures came in at 48.07% (Q1 2026), 47.99% (Q4 2025), and 81.15% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Krystal Biotech | 10.23 Bn | 9.41 Bn | 110.03 Mn | 48.07% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.07% |
| Dec 31, 2025 | 47.99% |
| Sep 30, 2025 | 81.15% |
| Jun 30, 2025 | 39.97% |
| Mar 31, 2025 | 40.52% |
| Dec 31, 2024 | 49.95% |
| Sep 30, 2024 | 32.42% |
| Jun 30, 2024 | 22.15% |
| Mar 31, 2024 | 2.06% |
| Dec 31, 2023 | 20.63% |
| Sep 30, 2023 | 943.75% |