Krystal Biotech (KRYS) Net Cash Flow (2016 - 2026)

Krystal Biotech (KRYS) posted quarterly Net Cash Flow of -$71.7 million for Q2 2026, down 263.05% year-over-year from $44.0 million in Q2 2025, and down 1231.58% on a QoQ basis from $6.3 million in Q1 2026.

Krystal Biotech (KRYS) Net Cash Flow (2016 - 2026) Analysis & Trends

Krystal Biotech has reported Net Cash Flow for 11 years, with the latest figure at -$71.7 million in Q2 2026.

  • Net Cash Flow for Q2 2026 came in at -$71.7 million, down 263.05% year-over-year; the trailing twelve-month figure through Jun 2026 was $78.0 million (up 995.59% YoY), and the FY2025 annual result was $151.2 million, up 1262.27% from the prior year.
  • Net Cash Flow eased to -$71.7 million in Q2 2026, from $6.3 million in the prior quarter.
  • Over five years, Net Cash Flow peaked at $135.1 million in Q2 2023 and troughed at -$71.9 million in Q1 2022.
  • A 5-year average of $5.0 million and a median of -$13.8 million in 2023 frame the typical range for Net Cash Flow.
  • The largest YoY upside for Net Cash Flow was 466.0% in 2025 against a maximum downside of 7486.15% in 2025.
  • A 5-year view of Net Cash Flow shows it stood at -$24.5 million in 2022, then surged by 39.62% to -$14.8 million in 2023, then plunged by 92.97% to -$28.5 million in 2024, then soared by 466.0% to $104.3 million in 2025, then plunged by 168.76% to -$71.7 million in 2026.
  • Per Business Quant data, the three most recent Net Cash Flow figures were -$71.7 million in Q2 2026, $6.3 million in Q1 2026, and $104.3 million in Q4 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 407.41 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 17.81 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -496,000.00
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.14 Mn
10 Krystal Biotech 9.83 Bn 8.99 Bn 112.79 Mn -71.74 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -71.74 Mn
Jun 30, 2026 -71.74 Mn
Mar 31, 2026 6.34 Mn
Mar 31, 2026 6.34 Mn
Dec 31, 2025 104.34 Mn
Dec 31, 2025 104.34 Mn
Sep 30, 2025 39.08 Mn
Sep 30, 2025 39.08 Mn
Jun 30, 2025 44.00 Mn
Jun 30, 2025 44.00 Mn
Mar 31, 2025 -36.27 Mn
Mar 31, 2025 -36.27 Mn
Dec 31, 2024 -28.51 Mn
Dec 31, 2024 -28.51 Mn
Sep 30, 2024 27.89 Mn
Sep 30, 2024 27.89 Mn
Jun 30, 2024 -12.88 Mn
Jun 30, 2024 -12.88 Mn
Mar 31, 2024 491,000.00
Mar 31, 2024 491,000.00