Krystal Biotech (KRYS) Gross Profit (2023 - 2026)

Krystal Biotech's (KRYS) quarterly Gross Profit came in at $110.0 million in Q1 2026, up 32.32% year-on-year from $83.2 million in Q1 2025, and up 9.48% quarter-over-quarter from $100.5 million in Q4 2025.

Krystal Biotech (KRYS) Gross Profit (2023 - 2026) Analysis & Trends

Krystal Biotech has disclosed Gross Profit across 4 years of filings, most recently posting $110.0 million for Q1 2026.

  • Gross Profit for Q1 2026 came in at $110.0 million, up 32.32% year-over-year; the trailing twelve-month figure through Mar 2026 was $392.9 million (up 26.43% YoY), and the FY2025 annual result was $366.1 million, up 35.35% from the prior year.
  • Gross Profit came in at $110.0 million for Q1 2026 at Krystal Biotech, up from $100.5 million in the prior quarter.
  • In the past five years, Gross Profit ranged from a high of $110.0 million in Q1 2026 to a low of $8.3 million in Q3 2023.
  • The 4-year median for Gross Profit is $83.2 million (2025), against an average of $72.2 million.
  • Across the five-year window, Gross Profit jumped 825.92% in 2024 and advanced 16.64% in 2025, its largest moves.
  • Krystal Biotech's Gross Profit stood at $39.3 million in 2023, then jumped by 119.41% to $86.2 million in 2024, then rose by 16.64% to $100.5 million in 2025, then grew by 9.48% to $110.0 million in 2026.
  • The last three Gross Profit figures came in at $110.0 million (Q1 2026), $100.5 million (Q4 2025), and $93.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 110.03 Mn
Mar 31, 2026 110.03 Mn
Dec 31, 2025 100.51 Mn
Dec 31, 2025 100.51 Mn
Sep 30, 2025 93.54 Mn
Sep 30, 2025 93.54 Mn
Jun 30, 2025 88.84 Mn
Jun 30, 2025 88.84 Mn
Mar 31, 2025 83.16 Mn
Mar 31, 2025 83.16 Mn
Dec 31, 2024 86.17 Mn
Dec 31, 2024 86.17 Mn
Sep 30, 2024 77.16 Mn
Sep 30, 2024 77.16 Mn
Jun 30, 2024 64.29 Mn
Jun 30, 2024 64.29 Mn
Mar 31, 2024 42.88 Mn
Mar 31, 2024 42.88 Mn
Dec 31, 2023 39.27 Mn
Dec 31, 2023 39.27 Mn