Growth Metrics

Krystal Biotech (KRYS) Gross Profit (2023 - 2026)

Krystal Biotech recorded quarterly Gross Profit of $110.0 million in Q1 2026, up 9.48% quarter-over-quarter from $100.5 million in Q4 2025, and up 32.32% year-over-year from $83.2 million in Q1 2025.

Krystal Biotech's Gross Profit history runs 4 years deep, the most recent figure standing at $110.0 million for Q1 2026.

  • In Q1 2026, Gross Profit rose 32.32% year-over-year to $110.0 million; the TTM figure through Mar 2026 stood at $392.9 million (up 26.43% YoY), while the FY2025 annual figure was $366.1 million, up 35.35% from the prior year.
  • Gross Profit came in at $110.0 million for Q1 2026 at Krystal Biotech, up from $100.5 million in the prior quarter.
  • In the past five years, Gross Profit ranged from a high of $110.0 million in Q1 2026 to a low of $8.3 million in Q3 2023.
  • A 4-year average of $72.2 million and a median of $83.2 million in 2025 frame the typical range for Gross Profit.
  • Across the five-year window, Gross Profit surged 825.92% in 2024 and climbed 16.64% in 2025, its largest moves.
  • Krystal Biotech's Gross Profit stood at $39.3 million in 2023, then surged by 119.41% to $86.2 million in 2024, then gained by 16.64% to $100.5 million in 2025, then increased by 9.48% to $110.0 million in 2026.
  • According to Business Quant data, Gross Profit over the past three periods registered $110.0 million, $100.5 million, and $93.5 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn
7 Evaxion A 64.16 Bn 64.14 Bn -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn
10 Krystal Biotech 9.05 Bn 8.23 Bn 110.03 Mn

Historic Data

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DateValue
Mar 31, 2026 110.03 Mn
Mar 31, 2026 110.03 Mn
Dec 31, 2025 100.51 Mn
Dec 31, 2025 100.51 Mn
Sep 30, 2025 93.54 Mn
Sep 30, 2025 93.54 Mn
Jun 30, 2025 88.84 Mn
Jun 30, 2025 88.84 Mn
Mar 31, 2025 83.16 Mn
Mar 31, 2025 83.16 Mn
Dec 31, 2024 86.17 Mn
Dec 31, 2024 86.17 Mn
Sep 30, 2024 77.16 Mn
Sep 30, 2024 77.16 Mn
Jun 30, 2024 64.29 Mn
Jun 30, 2024 64.29 Mn
Mar 31, 2024 42.88 Mn
Mar 31, 2024 42.88 Mn
Dec 31, 2023 39.27 Mn
Dec 31, 2023 39.27 Mn
Sep 30, 2023 8.33 Mn
Sep 30, 2023 8.33 Mn