Krystal Biotech (KRYS) Enterprise Value (2016 - 2026)

Krystal Biotech (KRYS) posted quarterly Enterprise Value of -$845.6 million for Q2 2026, down 24.0% year-over-year from -$1.1 billion in Q2 2025, and down 2.7% on a QoQ basis from -$823.4 million in Q1 2026.

Krystal Biotech (KRYS) Enterprise Value (2016 - 2026) Analysis & Trends

Krystal Biotech has reported Enterprise Value for 11 years, with the latest figure at -$845.6 million in Q2 2026.

  • Enterprise Value for Q2 2026 came in at -$845.6 million, down 24.0% year-over-year; the trailing twelve-month figure through Jun 2026 was -$845.6 million (down 24.0% YoY), and the FY2025 annual result was -$827.8 million, down 38.54% from the prior year.
  • Enterprise Value retreated to -$845.6 million in Q2 2026, from -$823.4 million in the prior quarter.
  • Over five years, Enterprise Value peaked at -$350.4 million in Q1 2023 and troughed at -$845.6 million in Q2 2026.
  • A 5-year average of -$575.9 million and a median of -$560.8 million in 2023 frame the typical range for Enterprise Value.
  • The widest annual swing landed in 2023, when Enterprise Value increased 19.38%; it then plunged 53.62% in 2024.
  • A 5-year view of Enterprise Value shows it stood at -$379.2 million in 2022, then slumped by 40.35% to -$532.2 million in 2023, then retreated by 12.28% to -$597.5 million in 2024, then slumped by 38.54% to -$827.8 million in 2025, then slipped by 2.16% to -$845.6 million in 2026.
  • Per Business Quant data, the three most recent Enterprise Value figures were -$845.6 million in Q2 2026, -$823.4 million in Q1 2026, and -$827.8 million in Q4 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 Krystal Biotech 9.83 Bn 8.99 Bn 112.79 Mn -845.63 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -845.63 Mn
Mar 31, 2026 -823.41 Mn
Dec 31, 2025 -827.79 Mn
Sep 30, 2025 -731.07 Mn
Jun 30, 2025 -681.99 Mn
Mar 31, 2025 -616.85 Mn
Dec 31, 2024 -597.52 Mn
Sep 30, 2024 -588.32 Mn
Jun 30, 2024 -559.61 Mn
Mar 31, 2024 -538.26 Mn
Dec 31, 2023 -532.18 Mn
Sep 30, 2023 -562.07 Mn
Jun 30, 2023 -477.52 Mn
Mar 31, 2023 -350.39 Mn
Dec 31, 2022 -379.17 Mn
Sep 30, 2022 -394.42 Mn
Jun 30, 2022 -425.57 Mn
Mar 31, 2022 -434.63 Mn
Dec 31, 2021 -438.10 Mn
Sep 30, 2021 -343.09 Mn