Krystal Biotech (KRYS) Enterprise Value (2016 - 2026)

Krystal Biotech's (KRYS) quarterly Enterprise Value came in at -$823.4 million in Q1 2026, down 33.49% year-on-year from -$1.2 billion in Q1 2025, and up 0.53% quarter-over-quarter from -$827.8 million in Q4 2025.

Krystal Biotech (KRYS) Enterprise Value (2016 - 2026) Analysis & Trends

Krystal Biotech has disclosed Enterprise Value across 11 years of filings, most recently posting -$823.4 million for Q1 2026.

  • Enterprise Value for Q1 2026 came in at -$823.4 million, down 33.49% year-over-year; the trailing twelve-month figure through Mar 2026 was -$823.4 million (down 33.49% YoY), and the FY2025 annual result was -$827.8 million, down 38.54% from the prior year.
  • Enterprise Value came in at -$823.4 million for Q1 2026 at Krystal Biotech, up from -$827.8 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$350.4 million in Q1 2023 to a low of -$827.8 million in Q4 2025.
  • The 5-year median for Enterprise Value is -$559.6 million (2024), against an average of -$560.0 million.
  • Across the five-year window, Enterprise Value increased 19.38% in 2023 and plunged 53.62% in 2024, its largest moves.
  • Krystal Biotech's Enterprise Value stood at -$379.2 million in 2022, then plunged by 40.35% to -$532.2 million in 2023, then declined by 12.28% to -$597.5 million in 2024, then plunged by 38.54% to -$827.8 million in 2025, then grew by 0.53% to -$823.4 million in 2026.
  • The last three Enterprise Value figures came in at -$823.4 million (Q1 2026), -$827.8 million (Q4 2025), and -$731.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -32.30 Mn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -4.14 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -286.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -18.44 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.77 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -7.25 Bn
9 Abivax 91.96 Bn 91.96 Bn - -584.73 Mn
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn -823.41 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -823.41 Mn
Dec 31, 2025 -827.79 Mn
Sep 30, 2025 -731.07 Mn
Jun 30, 2025 -681.99 Mn
Mar 31, 2025 -616.85 Mn
Dec 31, 2024 -597.52 Mn
Sep 30, 2024 -588.32 Mn
Jun 30, 2024 -559.61 Mn
Mar 31, 2024 -538.26 Mn
Dec 31, 2023 -532.18 Mn
Sep 30, 2023 -562.07 Mn
Jun 30, 2023 -477.52 Mn
Mar 31, 2023 -350.39 Mn
Dec 31, 2022 -379.17 Mn
Sep 30, 2022 -394.42 Mn
Jun 30, 2022 -425.57 Mn
Mar 31, 2022 -434.63 Mn
Dec 31, 2021 -438.10 Mn
Sep 30, 2021 -343.09 Mn
Jun 30, 2021 -367.73 Mn