Growth Metrics

Krystal Biotech (KRYS) Cost of Revenue (2023 - 2026)

Krystal Biotech recorded quarterly Cost of Revenue of $6.3 million in Q1 2026, down 4.08% quarter-over-quarter from $6.6 million in Q4 2025, and up 25.76% year-over-year from $5.0 million in Q1 2025.

Krystal Biotech's Cost of Revenue history runs 4 years deep, the most recent figure standing at $6.3 million for Q1 2026.

  • In Q1 2026, Cost of Revenue rose 25.76% year-over-year to $6.3 million; the TTM figure through Mar 2026 stood at $24.3 million (up 7.38% YoY), while the FY2025 annual figure was $23.0 million, up 14.89% from the prior year.
  • Cost of Revenue came in at $6.3 million for Q1 2026 at Krystal Biotech, down from $6.6 million in the prior quarter.
  • In the past five years, Cost of Revenue ranged from a high of $7.2 million in Q2 2025 to a low of $223000.0 in Q3 2023.
  • A 4-year average of $4.8 million and a median of $5.0 million in 2025 frame the typical range for Cost of Revenue.
  • Across the five-year window, Cost of Revenue soared 2897.31% in 2024 and plunged 36.22% in 2025, its largest moves.
  • Krystal Biotech's Cost of Revenue stood at $2.9 million in 2023, then jumped by 72.38% to $4.9 million in 2024, then jumped by 33.2% to $6.6 million in 2025, then decreased by 4.08% to $6.3 million in 2026.
  • According to Business Quant data, Cost of Revenue over the past three periods registered $6.3 million, $6.6 million, and $4.3 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cost of Rev (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn 64.20 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 392.80 Mn
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 296.00 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 207.52 Mn
10 Krystal Biotech 9.05 Bn 8.23 Bn 110.03 Mn 6.32 Mn

Historic Data

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DateValue
Mar 31, 2026 6.32 Mn
Mar 31, 2026 6.32 Mn
Dec 31, 2025 6.59 Mn
Dec 31, 2025 6.59 Mn
Sep 30, 2025 4.26 Mn
Sep 30, 2025 4.26 Mn
Jun 30, 2025 7.17 Mn
Jun 30, 2025 7.17 Mn
Mar 31, 2025 5.03 Mn
Mar 31, 2025 5.03 Mn
Dec 31, 2024 4.95 Mn
Dec 31, 2024 4.95 Mn
Sep 30, 2024 6.68 Mn
Sep 30, 2024 6.68 Mn
Jun 30, 2024 6.01 Mn
Jun 30, 2024 6.01 Mn
Mar 31, 2024 2.42 Mn
Mar 31, 2024 2.42 Mn
Dec 31, 2023 2.87 Mn
Dec 31, 2023 2.87 Mn
Sep 30, 2023 223,000.00
Sep 30, 2023 223,000.00