Krystal Biotech (KRYS) Change in Cash (2016 - 2026)
Krystal Biotech recorded quarterly Change in Cash of $5.0 million in Q1 2026, down 95.17% quarter-over-quarter from $103.7 million in Q4 2025, and up 113.88% year-over-year from $2.3 million in Q1 2025.
Krystal Biotech's Change in Cash history runs 11 years deep, the most recent figure standing at $5.0 million for Q1 2026.
- In Q1 2026, Change in Cash rose 113.88% year-over-year to $5.0 million; the TTM figure through Mar 2026 stood at $192.5 million (up 483.28% YoY), while the FY2025 annual figure was $151.4 million, up 1224.85% from the prior year.
- Change in Cash came in at $5.0 million for Q1 2026 at Krystal Biotech, down from $103.7 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $135.1 million in Q2 2023 to a low of -$71.9 million in Q1 2022.
- A 5-year average of $9.4 million and a median of -$13.2 million in 2024 frame the typical range for Change in Cash.
- On a YoY basis, Change in Cash climbed as much as 456.35% in 2025 and fell as far as 5423.75% in 2025.
- Krystal Biotech's Change in Cash stood at -$24.5 million in 2022, then soared by 39.15% to -$14.9 million in 2023, then slumped by 95.14% to -$29.1 million in 2024, then jumped by 456.35% to $103.7 million in 2025, then tumbled by 95.17% to $5.0 million in 2026.
- According to Business Quant data, Change in Cash over the past three periods registered $5.0 million, $103.7 million, and $38.8 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | 2.44 Mn |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | 623.00 Mn |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | -2.44 Mn |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 417.10 Mn |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | -153.10 Mn |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 53.61 Mn |
| 10 | Krystal Biotech | 9.05 Bn | 8.23 Bn | 110.03 Mn | 5.01 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 5.01 Mn |
| Dec 31, 2025 | 103.70 Mn |
| Sep 30, 2025 | 38.78 Mn |
| Jun 30, 2025 | 45.06 Mn |
| Mar 31, 2025 | -36.10 Mn |
| Dec 31, 2024 | -29.10 Mn |
| Sep 30, 2024 | 28.18 Mn |
| Jun 30, 2024 | -13.22 Mn |
| Mar 31, 2024 | 678,000.00 |
| Dec 31, 2023 | -14.91 Mn |
| Sep 30, 2023 | 97.37 Mn |
| Jun 30, 2023 | 135.13 Mn |
| Mar 31, 2023 | -21.16 Mn |
| Dec 31, 2022 | -24.51 Mn |
| Sep 30, 2022 | -32.31 Mn |
| Jun 30, 2022 | -50.58 Mn |
| Mar 31, 2022 | -71.94 Mn |
| Dec 31, 2021 | 54.63 Mn |
| Sep 30, 2021 | -42.91 Mn |
| Jun 30, 2021 | -72.65 Mn |
| Mar 31, 2021 | 133.90 Mn |
| Dec 31, 2020 | -14.10 Mn |
| Sep 30, 2020 | -9.31 Mn |
| Jun 30, 2020 | 111.45 Mn |
| Mar 31, 2020 | -7.29 Mn |
| Dec 31, 2019 | -7.29 Mn |
| Sep 30, 2019 | 8.22 Mn |
| Jun 30, 2019 | 88.57 Mn |
| Mar 31, 2019 | -5.66 Mn |
| Dec 31, 2018 | 57.00 Mn |
| Sep 30, 2018 | 4.85 Mn |
| Jun 30, 2018 | -5.42 Mn |
| Mar 31, 2018 | -2.36 Mn |
| Dec 31, 2017 | -2.98 Mn |
| Sep 30, 2017 | 49.05 Mn |
| Jun 30, 2017 | 1.56 Mn |
| Mar 31, 2017 | 36,000.00 |
| Dec 31, 2016 | 1.53 Mn |