Krystal Biotech (KRYS) Change in Cash (2016 - 2026)

Krystal Biotech's (KRYS) quarterly Change in Cash came in at $5.0 million in Q1 2026, up 113.88% year-on-year from $2.3 million in Q1 2025, and down 95.17% quarter-over-quarter from $103.7 million in Q4 2025.

Krystal Biotech (KRYS) Change in Cash (2016 - 2026) Analysis & Trends

Krystal Biotech has disclosed Change in Cash across 11 years of filings, most recently posting $5.0 million for Q1 2026.

  • Change in Cash for Q1 2026 came in at $5.0 million, up 113.88% year-over-year; the trailing twelve-month figure through Mar 2026 was $192.5 million (up 483.28% YoY), and the FY2025 annual result was $151.4 million, up 1224.85% from the prior year.
  • Change in Cash came in at $5.0 million for Q1 2026 at Krystal Biotech, down from $103.7 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $135.1 million in Q2 2023 to a low of -$71.9 million in Q1 2022.
  • The 5-year median for Change in Cash is -$13.2 million (2024), against an average of $9.4 million.
  • Peak annual rise in Change in Cash reached 456.35% in 2025, while the deepest fall reached 5423.75% in 2025.
  • Krystal Biotech's Change in Cash stood at -$24.5 million in 2022, then surged by 39.15% to -$14.9 million in 2023, then tumbled by 95.14% to -$29.1 million in 2024, then soared by 456.35% to $103.7 million in 2025, then plunged by 95.17% to $5.0 million in 2026.
  • The last three Change in Cash figures came in at $5.0 million (Q1 2026), $103.7 million (Q4 2025), and $38.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 623.00 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - -45.97 Mn
10 Krystal Biotech 10.23 Bn 9.41 Bn 110.03 Mn 5.01 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 5.01 Mn
Dec 31, 2025 103.70 Mn
Sep 30, 2025 38.78 Mn
Jun 30, 2025 45.06 Mn
Mar 31, 2025 -36.10 Mn
Dec 31, 2024 -29.10 Mn
Sep 30, 2024 28.18 Mn
Jun 30, 2024 -13.22 Mn
Mar 31, 2024 678,000.00
Dec 31, 2023 -14.91 Mn
Sep 30, 2023 97.37 Mn
Jun 30, 2023 135.13 Mn
Mar 31, 2023 -21.16 Mn
Dec 31, 2022 -24.51 Mn
Sep 30, 2022 -32.31 Mn
Jun 30, 2022 -50.58 Mn
Mar 31, 2022 -71.94 Mn
Dec 31, 2021 54.63 Mn
Sep 30, 2021 -42.91 Mn
Jun 30, 2021 -72.65 Mn