Krystal Biotech (KRYS) Change in Cash (2016 - 2026)
Krystal Biotech (KRYS) posted quarterly Change in Cash of -$73.6 million for Q2 2026, down 263.28% year-over-year from $45.1 million in Q2 2025, and down 1568.82% on a QoQ basis from $5.0 million in Q1 2026.
Krystal Biotech (KRYS) Change in Cash (2016 - 2026) Analysis & Trends
Krystal Biotech has reported Change in Cash for 11 years, with the latest figure at -$73.6 million in Q2 2026.
- Change in Cash for Q2 2026 came in at -$73.6 million, down 263.28% year-over-year; the trailing twelve-month figure through Jun 2026 was $73.9 million (up 818.95% YoY), and the FY2025 annual result was $151.4 million, up 1224.85% from the prior year.
- Change in Cash fell to -$73.6 million in Q2 2026, from $5.0 million in the prior quarter.
- Over five years, Change in Cash peaked at $135.1 million in Q2 2023 and troughed at -$73.6 million in Q2 2026.
- A 5-year average of $4.8 million and a median of -$14.1 million in 2023 frame the typical range for Change in Cash.
- The largest YoY upside for Change in Cash was 456.35% in 2025 against a maximum downside of 5423.75% in 2025.
- A 5-year view of Change in Cash shows it stood at -$24.5 million in 2022, then jumped by 39.15% to -$14.9 million in 2023, then sank by 95.14% to -$29.1 million in 2024, then surged by 456.35% to $103.7 million in 2025, then sank by 170.95% to -$73.6 million in 2026.
- Per Business Quant data, the three most recent Change in Cash figures were -$73.6 million in Q2 2026, $5.0 million in Q1 2026, and $103.7 million in Q4 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | - |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 374.50 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 427.25 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -1.97 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 225.59 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | -2.94 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -37.42 Mn |
| 10 | Krystal Biotech | 9.83 Bn | 8.99 Bn | 112.79 Mn | -73.57 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -73.57 Mn |
| Mar 31, 2026 | 5.01 Mn |
| Dec 31, 2025 | 103.70 Mn |
| Sep 30, 2025 | 38.78 Mn |
| Jun 30, 2025 | 45.06 Mn |
| Mar 31, 2025 | -36.10 Mn |
| Dec 31, 2024 | -29.10 Mn |
| Sep 30, 2024 | 28.18 Mn |
| Jun 30, 2024 | -13.22 Mn |
| Mar 31, 2024 | 678,000.00 |
| Dec 31, 2023 | -14.91 Mn |
| Sep 30, 2023 | 97.37 Mn |
| Jun 30, 2023 | 135.13 Mn |
| Mar 31, 2023 | -21.16 Mn |
| Dec 31, 2022 | -24.51 Mn |
| Sep 30, 2022 | -32.31 Mn |
| Jun 30, 2022 | -50.58 Mn |
| Mar 31, 2022 | -71.94 Mn |
| Dec 31, 2021 | 54.63 Mn |
| Sep 30, 2021 | -42.91 Mn |