International Stem Cell (ISCO) Gross Margin (2010 - 2026)
International Stem Cell's (ISCO) quarterly Gross Margin came in at 54.5% in Q2 2026, down 761.0% year-over-year from 8.25% in Q2 2025, and up 7.86% quarter-over-quarter from 50.53% in Q4 2025.
Analysis
International Stem Cell (ISCO) Gross Margin (2010 - 2026) Analysis & Trends
International Stem Cell (ISCO) has reported Gross Margin for 17 consecutive years, with 54.5% the latest figure, recorded in Q2 2026.
- On a quarterly basis, Gross Margin fell 761.0% year-over-year to 54.5% in Q2 2026; TTM through Jun 2026 was 55.86%, a 194.0% decrease from a year earlier, with the FY2025 full-year figure at 55.68%, down 289.0% from the prior year.
- Gross Margin was 54.5% for Q2 2026 at International Stem Cell, up from 50.53% in the prior quarter.
- Over five years, Gross Margin peaked at 64.58% in Q2 2022 and troughed at 50.53% in Q4 2025.
- A 5-year average of 58.13% and a median of 59.48% in 2022 frame the typical range for Gross Margin.
- Across the five-year window, Gross Margin jumped 659 bps in 2022 and sank 899 bps in 2025, its largest moves.
- Over 5 years, Gross Margin stood at 53.25% in 2022, then gained by 2 bps to 54.31% in 2023, then climbed by 10 bps to 59.53% in 2024, then decreased by 15 bps to 50.53% in 2025, then rose by 8 bps to 54.5% in 2026.
- The last three Gross Margin figures came in at 54.5% (Q2 2026), 50.53% (Q4 2025), and 55.76% (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Krystal Biotech | 10.27 Bn | 9.43 Bn | 112.79 Mn | 94.60% |
| 2 | CRISPR Therapeutics AG | 5.17 Bn | 5.17 Bn | - | - |
| 3 | Iovance Biotherapeutics | 3.79 Bn | 3.49 Bn | 55.72 Mn | 56.10% |
| 4 | Legend Biotech | 3.68 Bn | 2.71 Bn | 251.50 Mn | 64.90% |
| 5 | uniQure | 3.05 Bn | 3.05 Bn | 5.49 Mn | 94.01% |
| 6 | Beam Therapeutics | 2.65 Bn | 2.65 Bn | - | - |
| 7 | Precigen | 2.44 Bn | 2.44 Bn | 52.17 Mn | 94.90% |
| 8 | Sarepta Therapeutics | 2.33 Bn | 1.53 Bn | 251.87 Mn | 62.77% |
| 9 | Vericel | 1.99 Bn | 1.83 Bn | 56.40 Mn | 72.82% |
| 10 | International Stem Cell | 2.84 Mn | 1.75 Mn | 1.46 Mn | 54.50% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 54.50% |
| Dec 31, 2025 | 50.53% |
| Sep 30, 2025 | 55.76% |
| Jun 30, 2025 | 62.12% |
| Mar 31, 2025 | 53.41% |
| Dec 31, 2024 | 59.53% |
| Sep 30, 2024 | 55.30% |
| Jun 30, 2024 | 60.83% |
| Mar 31, 2024 | 58.34% |
| Dec 31, 2023 | 54.31% |
| Sep 30, 2023 | 60.42% |
| Jun 30, 2023 | 61.27% |
| Mar 31, 2023 | 60.50% |
| Dec 31, 2022 | 53.25% |
| Sep 30, 2022 | 59.48% |
| Jun 30, 2022 | 64.58% |
| Mar 31, 2022 | 64.11% |
| Dec 31, 2021 | 60.12% |
| Sep 30, 2021 | 55.81% |
| Jun 30, 2021 | 57.99% |