International Stem Cell (ISCO) Gross Margin (2010 - 2026)
International Stem Cell (ISCO) posted Gross Margin of 54.50% for Q2 2026, down 7.61 percentage points from 62.12% a year earlier.
Powered by 
Analysis
International Stem Cell (ISCO) Gross Margin (2010 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Gross Margin at International Stem Cell was 55.86%, down 1.94 percentage points year-over-year; for FY2025, it came in at 55.68%, down 2.89 percentage points from FY2024.
- Annual Gross Margin has declined for three consecutive years, with a five-year change of -5.30 percentage points (FY2020 to FY2025).
- In prior years, International Stem Cell's Gross Margin was 58.57% in FY2024 (-0.59 pp), 59.16% in FY2023 (-0.88 pp), 60.04% in FY2022 (+0.94 pp) and 59.10% in FY2021 (-1.89 pp).
- Quarterly Gross Margin has run from a low of 50.53% in Q4 2025 to a high of 64.58% in Q2 2022 over five years.
- On a year-over-year basis, Gross Margin increased in three of the last seven quarters, with an average year-over-year change of -2.81 percentage points.
- The strongest year-over-year quarter for Gross Margin in the past five years was Q2 2022, with a gain of 6.59 percentage points; the weakest was Q4 2025, with a drop of 8.99 percentage points.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,136.97 Bn | 1,105.55 Bn | 19.71 Bn | 85.78% |
| 2 | Johnson & Johnson | 619.72 Bn | 538.25 Bn | 17.26 Bn | 68.19% |
| 3 | AbbVie | 503.40 Bn | 476.52 Bn | 12.70 Bn | 74.74% |
| 4 | Merck | 370.15 Bn | 324.53 Bn | 12.21 Bn | 73.54% |
| 5 | Novartis Ag | 298.64 Bn | 262.63 Bn | 11.24 Bn | 78.02% |
| 6 | Astrazeneca | 261.07 Bn | 234.76 Bn | 12.86 Bn | 83.60% |
| 7 | Amgen | 237.00 Bn | 192.40 Bn | 7.24 Bn | 72.04% |
| 8 | Gilead Sciences | 191.24 Bn | 165.43 Bn | 6.22 Bn | 79.76% |
| 9 | Pfizer | 170.31 Bn | 116.96 Bn | 10.94 Bn | 72.78% |
| 10 | International Stem Cell | 1.36 Mn | -2.61 Mn | 1.46 Mn | 54.50% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 54.50% |
| Dec 31, 2025 | 50.53% |
| Sep 30, 2025 | 55.76% |
| Jun 30, 2025 | 62.12% |
| Mar 31, 2025 | 53.41% |
| Dec 31, 2024 | 59.53% |
| Sep 30, 2024 | 55.30% |
| Jun 30, 2024 | 60.83% |
| Mar 31, 2024 | 58.34% |
| Dec 31, 2023 | 54.31% |
| Sep 30, 2023 | 60.42% |
| Jun 30, 2023 | 61.27% |
| Mar 31, 2023 | 60.50% |
| Dec 31, 2022 | 53.25% |
| Sep 30, 2022 | 59.48% |
| Jun 30, 2022 | 64.58% |
| Mar 31, 2022 | 64.11% |
| Dec 31, 2021 | 60.12% |
| Sep 30, 2021 | 55.81% |
| Jun 30, 2021 | 57.99% |
API Access
International Stem Cell Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=ISCO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "ISCO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=ISCO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();