Iovance Biotherapeutics (IOVA) Return on Capital Employed (2011 - 2026)

Iovance Biotherapeutics (IOVA) posted quarterly Return on Capital Employed of 45.97% for Q1 2026, up 290.0% year-over-year from 11.79% in Q1 2025, and up 12.16% quarter-over-quarter from 52.34% in Q4 2025.

Iovance Biotherapeutics (IOVA) Return on Capital Employed (2011 - 2026) Analysis & Trends

Iovance Biotherapeutics (IOVA) has reported Return on Capital Employed for 15 consecutive years, with 45.97% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Capital Employed rose 290.0% year-over-year to 45.97%; the TTM figure through Mar 2026 stood at 45.97% (up 290.0% YoY), while the FY2025 annual figure was 52.15%, up 252.0% from the prior year.
  • Return on Capital Employed climbed to 45.97% in Q1 2026 per IOVA's latest filing, from 52.34% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 45.97% in Q1 2026 and bottomed at 78.39% in Q3 2022.
  • Historically, Return on Capital Employed has averaged 60.05% across 5 years, with a median of 61.76% in 2023.
  • Annual changes were most pronounced in 2022 — Return on Capital Employed tumbled 3822 bps — and 2023, when it surged 1587 bps.
  • Iovance Biotherapeutics' Return on Capital Employed stood at 77.68% in 2022, then increased by 16 bps to 65.23% in 2023, then advanced by 3 bps to 63.01% in 2024, then climbed by 17 bps to 52.34% in 2025, then climbed by 12 bps to 45.97% in 2026.
  • Business Quant data shows IOVA's Return on Capital Employed at 45.97% in Q1 2026, 52.34% in Q4 2025, and 53.37% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 10.74%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -55.45%
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -0.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 7.88%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 26.09%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -50.93%
10 Iovance Biotherapeutics 3.16 Bn 2.86 Bn 55.72 Mn -37.03%

Historic Data

Download Data
DateValue
Jun 30, 2026 -37.03%
Mar 31, 2026 -45.97%
Dec 31, 2025 -52.34%
Sep 30, 2025 -53.37%
Jun 30, 2025 -50.83%
Mar 31, 2025 -48.88%
Mar 31, 2024 -63.01%
Dec 31, 2023 -65.23%
Sep 30, 2023 -62.53%
Jun 30, 2023 -60.99%
Mar 31, 2023 -63.62%
Dec 31, 2022 -77.68%
Sep 30, 2022 -78.39%
Jun 30, 2022 -63.72%
Mar 31, 2022 -54.19%
Dec 31, 2021 -48.01%
Sep 30, 2021 -40.17%
Jun 30, 2021 -38.39%
Mar 31, 2021 -37.86%
Dec 31, 2020 -36.35%