Iovance Biotherapeutics, Inc. (IOVA) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

334,145,378Shares Outstanding

34,646,581Shares held by institutions

$90,774,042Value of institutional holdings

77.62%Institutional ownership %

25.97%Shares Changed QoQ

250No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, Iovance Biotherapeutics, Inc. (NASDAQ:IOVA) is held by 250 institutional firms.

The percentage of Iovance Biotherapeutics owned by institutions changed from 63.8% in September 2025 to 77.6% in December 2025, marking a slight up trend.
Quarterly data indicates a 25.97% shift in institutional share volume, and the annual owner count reflects a decrease of 16.39%.
During the quarter, 149 institutions bought more Iovance Biotherapeutics shares, 59 sold shares, and 42 of the 250 total investors held their position steady.
Collectively, institutional investors increased their stake in Iovance Biotherapeutics to 259.38Mn shares as of December 2025, a change that is up by 53.47Mn shares quarter on quarter and up 22.58Mn shares year over year.
BlackRock, Inc.'s holding of 29.52Mn shares as of December 31, 2025 makes it the primary institutional investor in Iovance Biotherapeutics, owning 8.83% of the stock.
Among the most significant buyers of Iovance Biotherapeutics during December 2025 were BANK OF AMERICA CORP /DE/ (8.00Mn), STATE STREET CORP (6.85Mn), HRT FINANCIAL LP (3.99Mn), D. E. Shaw & Co., Inc. (3.75Mn), MORGAN STANLEY (3.61Mn).
Leading sellers of Iovance Biotherapeutics stock in December 2025 included PRINCIPAL FINANCIAL GROUP INC (3.00Mn), DIMENSIONAL FUND ADVISORS LP (1.28Mn), ROYAL BANK OF CANADA (946.35K), CITADEL ADVISORS LLC (677.27K), Long Focus Capital Management, LLC (516.51K).
The top 10 institutional holders of Iovance Biotherapeutics for the quarter ending December 2025 included BlackRock, Inc. (29.52Mn), MHR FUND MANAGEMENT LLC (28.97Mn), VANGUARD GROUP INC (27.21Mn), STATE STREET CORP (20.16Mn), BANK OF AMERICA CORP /DE/ (14.28Mn), Invenomic Capital Management LP (11.96Mn), MORGAN STANLEY (9.19Mn), GOLDMAN SACHS GROUP INC (8.61Mn), Long Focus Capital Management, LLC (8.60Mn), GEODE CAPITAL MANAGEMENT, LLC (7.99Mn).

250 Institutional Holders

34,646,581 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	29,518,125	3,561,836	13.72%	$80,584,481.00
MHR FUND MANAGEMENT LLC	31 Dec, 2025	28,967,103	0	0.00%	$79,080,191.00
VANGUARD GROUP INC	31 Dec, 2025	27,207,079	3,148,096	13.08%	$74,275,326.00
STATE STREET CORP	31 Dec, 2025	20,161,445	6,851,486	51.48%	$55,040,745.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	14,277,813	7,998,583	127.38%	$38,978,430.00
Invenomic Capital Management LP	31 Dec, 2025	11,959,505	1,417,897	13.45%	$32,649,449.00
MORGAN STANLEY	31 Dec, 2025	9,191,840	3,610,277	64.68%	$25,093,723.00
GOLDMAN SACHS GROUP INC	31 Dec, 2025	8,607,564	2,032,062	30.90%	$23,498,650.00
Long Focus Capital Management, LLC	31 Dec, 2025	8,600,000	-516,507	-5.67%	$23,478,000.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	7,991,640	1,123,337	16.36%	$21,820,558.00
Palo Alto Investors LP	31 Dec, 2025	7,116,676	-501,456	-6.58%	$19,428,525.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	6,986,032	2,572,581	58.29%	$19,071,867.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	4,948,614	1,642,098	49.66%	$13,509,716.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	4,397,989	1,657,135	60.46%	$12,006,510.00
HRT FINANCIAL LP	31 Dec, 2025	4,356,010	3,986,314	1,078.27%	$11,891.00
JANE STREET GROUP, LLC	31 Dec, 2025	3,837,210	2,252,748	142.18%	$10,475,583.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	3,829,795	3,753,586	4,925.38%	$10,455,340.00
CITADEL ADVISORS LLC	31 Dec, 2025	3,143,091	-677,273	-17.73%	$8,580,638.00
TWO SIGMA ADVISERS, LP	31 Dec, 2025	3,015,000	1,956,000	184.70%	$8,230,950.00
JPMORGAN CHASE & CO	31 Dec, 2025	3,001,502	1,777,671	145.25%	$8,194,101.00

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