Illumina (ILMN) Operating Margin (2009 - 2026)
Illumina (ILMN) recorded Operating Margin of 21.14% in Q2 2026, up 0.93 percentage points from 20.21% a year earlier and up 1.98 percentage points from the prior quarter.
Illumina (ILMN) Operating Margin (2009 - 2026) Analysis & Trends
On a TTM basis, Illumina's Operating Margin came in at 19.63% as of Jun 28, 2026, down 10.57 percentage points year-over-year; for FY2025, it was 18.58%, up 37.63 percentage points from FY2024.
- Annual Operating Margin has increased for three straight years, with a four-year change of +0.67 percentage points (FY2021 to FY2025).
- Across earlier years, Operating Margin came in at -19.05% in FY2024 (+4.68 pp), -23.73% in FY2023 (+67.43 pp), -91.16% in FY2022 and 17.91% in FY2021.
- The Q2 2026 figure is the highest quarterly Operating Margin since Q3 2024.
- On a year-over-year basis, Operating Margin has increased for three consecutive quarters, with an average year-over-year change of +39.76 percentage points over the last eight quarters.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 304.79 percentage points in Q4 2023, against a drop of 139.73 percentage points in Q2 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at 19.16% (Q1 2026), 17.34% (Q4 2025) and 20.94% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 261.60 Bn | 238.24 Bn | 5.13 Bn | 18.65% |
| 2 | Abbott Laboratories | 199.98 Bn | 171.06 Bn | 7.27 Bn | 13.44% |
| 3 | Intuitive Surgical | 167.10 Bn | 147.52 Bn | 2.08 Bn | 19.44% |
| 4 | Danaher | 165.26 Bn | 144.92 Bn | 3.84 Bn | 19.00% |
| 5 | Medtronic | 134.46 Bn | 100.33 Bn | 6.34 Bn | 18.08% |
| 6 | Stryker | 129.35 Bn | 115.54 Bn | 4.25 Bn | 15.86% |
| 7 | Boston Scientific | 66.41 Bn | 62.09 Bn | 3.43 Bn | 16.12% |
| 8 | Edwards Lifesciences | 57.13 Bn | 40.44 Bn | 1.35 Bn | 17.44% |
| 9 | Becton Dickinson | 56.98 Bn | 54.13 Bn | 2.32 Bn | 13.31% |
| 10 | Illumina | 34.25 Bn | 28.96 Bn | 830.00 Mn | 27.02% |
Historic Data
| Date | Value |
|---|---|
| Sep 27, 2026 | 27.02% |
| Jun 28, 2026 | 21.14% |
| Mar 29, 2026 | 19.16% |
| Dec 28, 2025 | 17.34% |
| Sep 28, 2025 | 20.94% |
| Jun 29, 2025 | 20.21% |
| Mar 30, 2025 | 15.75% |
| Dec 29, 2024 | 15.85% |
| Sep 29, 2024 | 68.61% |
| Jun 30, 2024 | -147.21% |
| Mar 31, 2024 | -10.32% |
| Dec 31, 2023 | -14.62% |
| Oct 1, 2023 | -67.38% |
| Jul 2, 2023 | -7.48% |
| Apr 2, 2023 | -5.89% |
| Jan 1, 2023 | -319.41% |
| Oct 2, 2022 | -327.98% |
| Jul 3, 2022 | -49.83% |
| Apr 3, 2022 | 15.04% |
| Oct 3, 2021 | -49.19% |
Illumina Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=ILMN&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "ILMN", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=ILMN&period=max&api_key=YOUR_API_KEY");
const data = await res.json();