KPIs & Operating Metrics(New)
Growth Metrics

Illumina (ILMN) Operating Margin (2016 - 2025)

Illumina's Operating Margin history spans 17 years, with the latest figure at 17.34% for Q4 2025.

  • For Q4 2025, Operating Margin rose 149.0% year-over-year to 17.34%; the TTM value through Dec 2025 reached 18.56%, up 3759.0%, while the annual FY2025 figure was 18.58%, 3763.0% up from the prior year.
  • Operating Margin reached 17.34% in Q4 2025 per ILMN's latest filing, down from 20.94% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 68.61% in Q3 2024 to a low of 327.98% in Q4 2022.
  • Average Operating Margin over 5 years is 38.87%, with a median of 4.03% recorded in 2021.
  • Peak YoY movement for Operating Margin: tumbled -27879bps in 2022, then surged 30479bps in 2023.
  • A 5-year view of Operating Margin shows it stood at 49.19% in 2021, then crashed by -567bps to 327.98% in 2022, then soared by 96bps to 14.62% in 2023, then surged by 208bps to 15.85% in 2024, then increased by 9bps to 17.34% in 2025.
  • Per Business Quant, the three most recent readings for ILMN's Operating Margin are 17.34% (Q4 2025), 20.94% (Q3 2025), and 20.21% (Q2 2025).