Illumina (ILMN) Operating Margin (2009 - 2026)
Illumina (ILMN) reported Operating Margin of 19.16% for Q1 2026, up 340.0% on a YoY basis from 4.35% in Q1 2025, and up 10.46% quarter-over-quarter from 17.34% in Q4 2025.
Illumina (ILMN) Operating Margin (2009 - 2026) Analysis & Trends
Illumina has reported Operating Margin for 18 years, with the latest figure at 19.16% in Q1 2026.
- For the quarter ending Q1 2026, Operating Margin rose 340.0% year-over-year to 19.16%; the trailing twelve-month figure through Mar 2026 stood at 19.37% (up 3221.0% YoY), and the FY2025 full-year result was 18.58%, up 3763.0% from the prior year.
- Operating Margin for Q1 2026 stood at 19.16%, up from 17.34% in the prior quarter.
- The five-year high for Operating Margin was 68.61% in Q3 2024, with the low at 327.98% in Q4 2022.
- Historically, Operating Margin has averaged 44.54% across 5 years, with a median of 5.89% in 2023.
- Annual changes were most pronounced in 2022 — Operating Margin plunged 27879 bps — and 2023, when it jumped 30479 bps.
- Illumina's Operating Margin stood at 327.98% in 2022, then jumped by 96 bps to 14.62% in 2023, then soared by 208 bps to 15.85% in 2024, then climbed by 9 bps to 17.34% in 2025, then rose by 10 bps to 19.16% in 2026.
- The last three Operating Margin figures came in at 19.16% (Q1 2026), 17.34% (Q4 2025), and 20.94% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | -3.71% |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 16.93% |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 22.58% |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 31.78% |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 21.74% |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 12.38% |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | -13.42% |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 19.16% |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 25.23% |
| 10 | Quest Diagnostics | 21.68 Bn | 21.59 Bn | 942.00 Mn | 13.78% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 29, 2026 | 19.16% |
| Dec 28, 2025 | 17.34% |
| Sep 28, 2025 | 20.94% |
| Jun 29, 2025 | 20.21% |
| Mar 30, 2025 | 15.75% |
| Dec 29, 2024 | 15.85% |
| Sep 29, 2024 | 68.61% |
| Jun 30, 2024 | -147.21% |
| Mar 31, 2024 | -10.32% |
| Dec 31, 2023 | -14.62% |
| Oct 1, 2023 | -67.38% |
| Jul 2, 2023 | -7.48% |
| Apr 2, 2023 | -5.89% |
| Jan 1, 2023 | -319.41% |
| Oct 2, 2022 | -327.98% |
| Jul 3, 2022 | -49.83% |
| Apr 3, 2022 | 15.04% |
| Oct 3, 2021 | -49.19% |
| Jul 4, 2021 | 16.61% |
| Apr 4, 2021 | 17.66% |