KPIs & Operating Metrics(New)
Growth Metrics

Illumina (ILMN) Operating Margin (2016 - 2025)

Illumina (ILMN) has disclosed Operating Margin for 17 consecutive years, with 17.34% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Operating Margin rose 158.0% year-over-year to 17.34%, compared with a TTM value of 18.58% through Dec 2025, up 3763.0%, and an annual FY2025 reading of 18.58%, up 3763.0% over the prior year.
  • Operating Margin was 17.34% for Q4 2025 at Illumina, down from 21.03% in the prior quarter.
  • Across five years, Operating Margin topped out at 3968.42% in Q4 2023 and bottomed at 327.98% in Q4 2022.
  • Average Operating Margin over 5 years is 186.46%, with a median of 15.4% recorded in 2022.
  • The sharpest move saw Operating Margin surged 429640bps in 2023, then tumbled -389981bps in 2024.
  • Year by year, Operating Margin stood at 49.19% in 2021, then crashed by -567bps to 327.98% in 2022, then soared by 96bps to 14.62% in 2023, then surged by 208bps to 15.76% in 2024, then rose by 10bps to 17.34% in 2025.
  • Business Quant data shows Operating Margin for ILMN at 17.34% in Q4 2025, 21.03% in Q3 2025, and 20.21% in Q2 2025.