Illumina (ILMN) Operating Income (2009 - 2026)

Illumina (ILMN) reported Operating Income of $209.0 million for Q1 2026, up 27.44% on a YoY basis from $164.0 million in Q1 2025, and up 3.98% quarter-over-quarter from $201.0 million in Q4 2025.

Illumina (ILMN) Operating Income (2009 - 2026) Analysis & Trends

Illumina has reported Operating Income for 18 years, with the latest figure at $209.0 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income rose 27.44% year-over-year to $209.0 million; the trailing twelve-month figure through Mar 2026 stood at $851.0 million (up 252.78% YoY), and the FY2025 full-year result was $807.0 million, up 196.88% from the prior year.
  • Operating Income for Q1 2026 stood at $209.0 million, up from $201.0 million in the prior quarter.
  • The five-year high for Operating Income was $741.0 million in Q3 2024, with the low at -$4.0 billion in Q1 2023.
  • Historically, Operating Income has averaged -$526.7 million across 5 years, with a median of -$64.0 million in 2023.
  • Annual changes were most pronounced in 2024 — Operating Income tumbled 1760.23% — and 2025, when it soared 247.75%.
  • Illumina's Operating Income stood at -$3.7 billion in 2022, then jumped by 95.52% to -$164.0 million in 2023, then jumped by 206.71% to $175.0 million in 2024, then grew by 14.86% to $201.0 million in 2025, then rose by 3.98% to $209.0 million in 2026.
  • The last three Operating Income figures came in at $209.0 million (Q1 2026), $201.0 million (Q4 2025), and $227.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn -47.00 Mn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 1.86 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 1.34 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 362.59 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 399.00 Mn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 514.00 Mn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn -93.52 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 209.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 238.95 Mn
10 Quest Diagnostics 21.68 Bn 21.59 Bn 942.00 Mn 399.00 Mn

Historic Data

Download Data
DateValue
Mar 29, 2026 209.00 Mn
Dec 28, 2025 201.00 Mn
Sep 28, 2025 227.00 Mn
Jun 29, 2025 214.00 Mn
Mar 30, 2025 164.00 Mn
Dec 29, 2024 175.00 Mn
Sep 29, 2024 741.00 Mn
Jun 30, 2024 -1.64 Bn
Mar 31, 2024 -111.00 Mn
Dec 31, 2023 -164.00 Mn
Oct 1, 2023 -754.00 Mn
Jul 2, 2023 -88.00 Mn
Apr 2, 2023 -64.00 Mn
Jan 1, 2023 -4.02 Bn
Oct 2, 2022 -3.66 Bn
Jul 3, 2022 -579.00 Mn
Apr 3, 2022 184.00 Mn
Oct 3, 2021 -545.00 Mn
Jul 4, 2021 187.00 Mn
Apr 4, 2021 193.00 Mn