Harmony Biosciences Holdings (HRMY) Gross Margin (2020 - 2026)
Harmony Biosciences Holdings (HRMY) reported Gross Margin of 79.33% for Q1 2026, down 335.0% on a YoY basis from 33.76% in Q1 2025, and up 10.37% sequentially from 71.88% in Q4 2025.
Harmony Biosciences Holdings (HRMY) Gross Margin (2020 - 2026) Analysis & Trends
Harmony Biosciences Holdings (HRMY) has 7 years of Gross Margin data on file, last reported at 79.33% in Q1 2026.
- For the quarter ending Q1 2026, Gross Margin fell 335.0% year-over-year to 79.33%; the trailing twelve-month figure through Mar 2026 stood at 76.55% (down 179.0% YoY), and the FY2025 full-year result was 77.16%, down 90.0% from the prior year.
- Gross Margin grew to 79.33% in Q1 2026, from 71.88% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 82.75% in Q1 2022 to a low of 71.88% in Q4 2025.
- A 5-year average of 79.19% and a median of 80.41% in 2022 frame the typical range for Gross Margin.
- Across the five-year window, Gross Margin slumped 467 bps in 2023 and jumped 46 bps in 2025, its largest moves.
- Tracing HRMY's Gross Margin over 5 years: stood at 79.05% in 2022, then retreated by 6 bps to 74.38% in 2023, then declined by 2 bps to 72.97% in 2024, then dropped by 1 bps to 71.88% in 2025, then climbed by 10 bps to 79.33% in 2026.
- Business Quant data shows HRMY's Gross Margin at 79.33% in Q1 2026, 71.88% in Q4 2025, and 75.09% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 88.95% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 90.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Harmony Biosciences Holdings | 2.07 Bn | 1.55 Bn | 170.88 Mn | 79.33% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 79.33% |
| Dec 31, 2025 | 71.88% |
| Sep 30, 2025 | 75.09% |
| Jun 30, 2025 | 80.97% |
| Mar 31, 2025 | 82.68% |
| Dec 31, 2024 | 72.97% |
| Sep 30, 2024 | 77.01% |
| Jun 30, 2024 | 81.40% |
| Mar 31, 2024 | 82.22% |
| Dec 31, 2023 | 74.38% |
| Sep 30, 2023 | 79.85% |
| Jun 30, 2023 | 81.37% |
| Mar 31, 2023 | 82.56% |
| Dec 31, 2022 | 79.05% |
| Sep 30, 2022 | 80.41% |
| Jun 30, 2022 | 82.32% |
| Mar 31, 2022 | 82.75% |
| Dec 31, 2021 | 80.47% |
| Sep 30, 2021 | 81.91% |
| Jun 30, 2021 | 82.81% |