HCW Biologics (HCWB) Gross Margin (2022 - 2025)
HCW Biologics' (HCWB) quarterly Gross Margin came in at 20.0% in Q4 2025, little changed YoY from 20.0% in Q4 2024, and little changed on a QoQ basis from 20.0% in Q3 2025.
HCW Biologics (HCWB) Gross Margin (2022 - 2025) Analysis & Trends
HCW Biologics (HCWB) has 4 years of Gross Margin data on file, last reported at 20.0% in Q4 2025.
- Quarterly Gross Margin changed 0.0% year-over-year to 20.0% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 20.0% (down 1738.0% YoY) and the FY2025 annual result came in at 20.0%, down 1738.0% from the prior year.
- Gross Margin was little changed at 20.0% in Q4 2025, from 20.0% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 57.4% in Q1 2022 to a low of 19.08% in Q4 2023.
- A 4-year average of 26.67% and a median of 20.0% in 2022 frame the typical range for Gross Margin.
- Annual changes were most pronounced in 2024 — Gross Margin surged 2464 bps — and 2025, when it slumped 3456 bps.
- Tracing HCWB's Gross Margin over 4 years: stood at 20.0% in 2022, then retreated by 5 bps to 19.08% in 2023, then advanced by 5 bps to 20.0% in 2024, then declined by 0 bps to 20.0% in 2025.
- The last three Gross Margin figures came in at 20.0% (Q4 2025), 20.0% (Q3 2025), and 20.0% (Q2 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 90.43% |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | 35.86% |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 89.76% |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 76.90% |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | 84.20% |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | - |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | 63.27% |
| 10 | HCW Biologics | 2.93 Mn | 2.19 Mn | -93,887.00 | -69.25% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 20.00% |
| Sep 30, 2025 | 20.00% |
| Jun 30, 2025 | 20.00% |
| Mar 31, 2025 | 20.00% |
| Dec 31, 2024 | 20.00% |
| Sep 30, 2024 | 20.00% |
| Jun 30, 2024 | 29.15% |
| Mar 31, 2024 | 54.56% |
| Dec 31, 2023 | 19.08% |
| Sep 30, 2023 | 20.49% |
| Jun 30, 2023 | 19.33% |
| Mar 31, 2023 | 29.92% |
| Dec 31, 2022 | 20.00% |
| Sep 30, 2022 | 20.00% |
| Jun 30, 2022 | 36.74% |
| Mar 31, 2022 | 57.40% |