Grail (GRAL) Operating Income (2023 - 2026)

Grail (GRAL) reported Operating Income of -$135.8 million for Q1 2026, up 11.62% on a YoY basis from -$121.6 million in Q1 2025, and down 9.13% quarter-over-quarter from -$124.4 million in Q4 2025.

Grail (GRAL) Operating Income (2023 - 2026) Analysis & Trends

Grail has reported Operating Income for 4 years, with the latest figure at -$135.8 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income rose 11.62% year-over-year to -$135.8 million; the trailing twelve-month figure through Mar 2026 stood at -$544.3 million (up 74.27% YoY), and the FY2025 full-year result was -$562.2 million, up 74.32% from the prior year.
  • Operating Income for Q1 2026 stood at -$135.8 million, down from -$124.4 million in the prior quarter.
  • The five-year high for Operating Income was -$124.4 million in Q4 2025, with the low at -$1.6 billion in Q2 2024.
  • Historically, Operating Income has averaged -$349.9 million across 4 years, with a median of -$171.2 million in 2024.
  • Annual changes were most pronounced in 2024 — Operating Income sank 703.11% — and 2025, when it jumped 90.32%.
  • Grail's Operating Income stood at -$194.6 million in 2023, then increased by 29.63% to -$136.9 million in 2024, then increased by 9.15% to -$124.4 million in 2025, then fell by 9.13% to -$135.8 million in 2026.
  • The last three Operating Income figures came in at -$135.8 million (Q1 2026), -$124.4 million (Q4 2025), and -$125.3 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn -47.00 Mn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 1.86 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 1.34 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 362.59 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 399.00 Mn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 514.00 Mn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn -93.52 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 209.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 238.95 Mn
10 Grail 2.49 Bn 2.49 Bn 10.12 Mn -135.77 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -135.77 Mn
Dec 31, 2025 -124.41 Mn
Sep 30, 2025 -125.29 Mn
Jun 30, 2025 -158.85 Mn
Mar 31, 2025 -153.61 Mn
Dec 31, 2024 -136.94 Mn
Sep 30, 2024 -183.51 Mn
Jun 30, 2024 -1.64 Bn
Mar 31, 2024 -227.42 Mn
Dec 31, 2023 -194.59 Mn
Oct 1, 2023 -912.39 Mn
Jun 30, 2023 -204.37 Mn