Guardant Health (GH) Operating Income (2017 - 2026)
Guardant Health's (GH) quarterly Operating Income came in at -$121.4 million in Q1 2026, down 9.28% year-on-year from -$133.8 million in Q1 2025, and little changed quarter-over-quarter from -$120.8 million in Q4 2025.
Guardant Health (GH) Operating Income (2017 - 2026) Analysis & Trends
Guardant Health has disclosed Operating Income across 10 years of filings, most recently posting -$121.4 million for Q1 2026.
- Operating Income for Q1 2026 came in at -$121.4 million, down 9.28% year-over-year; the trailing twelve-month figure through Mar 2026 was -$447.6 million (up 1.63% YoY), and the FY2025 annual result was -$437.2 million, up 1.43% from the prior year.
- Operating Income came in at -$121.4 million for Q1 2026 at Guardant Health, roughly flat from -$120.8 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$99.0 million in Q3 2025 to a low of -$197.5 million in Q4 2023.
- The 5-year median for Operating Income is -$120.8 million (2025), against an average of -$124.2 million.
- Across the five-year window, Operating Income slumped 48.79% in 2022 and surged 36.22% in 2024, its largest moves.
- Guardant Health's Operating Income stood at -$146.1 million in 2022, then slumped by 35.17% to -$197.5 million in 2023, then soared by 36.22% to -$126.0 million in 2024, then rose by 4.1% to -$120.8 million in 2025, then retreated by 0.45% to -$121.4 million in 2026.
- The last three Operating Income figures came in at -$121.4 million (Q1 2026), -$120.8 million (Q4 2025), and -$99.0 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | -47.00 Mn |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 1.86 Bn |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 1.34 Bn |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 362.59 Mn |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 399.00 Mn |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 514.00 Mn |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | -93.52 Mn |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 209.00 Mn |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 238.95 Mn |
| 10 | Guardant Health | 16.38 Bn | 15.28 Bn | 196.75 Mn | -121.35 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -121.35 Mn |
| Dec 31, 2025 | -120.81 Mn |
| Sep 30, 2025 | -98.99 Mn |
| Jun 30, 2025 | -106.41 Mn |
| Mar 31, 2025 | -111.04 Mn |
| Dec 31, 2024 | -125.97 Mn |
| Sep 30, 2024 | -117.33 Mn |
| Jun 30, 2024 | -100.62 Mn |
| Mar 31, 2024 | -99.68 Mn |
| Dec 31, 2023 | -197.51 Mn |
| Sep 30, 2023 | -113.54 Mn |
| Jun 30, 2023 | -119.62 Mn |
| Mar 31, 2023 | -134.06 Mn |
| Dec 31, 2022 | -146.12 Mn |
| Sep 30, 2022 | -144.60 Mn |
| Jun 30, 2022 | -130.32 Mn |
| Mar 31, 2022 | -123.34 Mn |
| Dec 31, 2021 | -98.21 Mn |
| Sep 30, 2021 | -107.29 Mn |
| Jun 30, 2021 | -97.64 Mn |