Guardant Health (GH) Operating Income (2017 - 2026)

Guardant Health's (GH) quarterly Operating Income came in at -$121.4 million in Q1 2026, down 9.28% year-on-year from -$133.8 million in Q1 2025, and little changed quarter-over-quarter from -$120.8 million in Q4 2025.

Guardant Health (GH) Operating Income (2017 - 2026) Analysis & Trends

Guardant Health has disclosed Operating Income across 10 years of filings, most recently posting -$121.4 million for Q1 2026.

  • Operating Income for Q1 2026 came in at -$121.4 million, down 9.28% year-over-year; the trailing twelve-month figure through Mar 2026 was -$447.6 million (up 1.63% YoY), and the FY2025 annual result was -$437.2 million, up 1.43% from the prior year.
  • Operating Income came in at -$121.4 million for Q1 2026 at Guardant Health, roughly flat from -$120.8 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$99.0 million in Q3 2025 to a low of -$197.5 million in Q4 2023.
  • The 5-year median for Operating Income is -$120.8 million (2025), against an average of -$124.2 million.
  • Across the five-year window, Operating Income slumped 48.79% in 2022 and surged 36.22% in 2024, its largest moves.
  • Guardant Health's Operating Income stood at -$146.1 million in 2022, then slumped by 35.17% to -$197.5 million in 2023, then soared by 36.22% to -$126.0 million in 2024, then rose by 4.1% to -$120.8 million in 2025, then retreated by 0.45% to -$121.4 million in 2026.
  • The last three Operating Income figures came in at -$121.4 million (Q1 2026), -$120.8 million (Q4 2025), and -$99.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn -47.00 Mn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 1.86 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 1.34 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 362.59 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 399.00 Mn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 514.00 Mn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn -93.52 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 209.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 238.95 Mn
10 Guardant Health 16.38 Bn 15.28 Bn 196.75 Mn -121.35 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -121.35 Mn
Dec 31, 2025 -120.81 Mn
Sep 30, 2025 -98.99 Mn
Jun 30, 2025 -106.41 Mn
Mar 31, 2025 -111.04 Mn
Dec 31, 2024 -125.97 Mn
Sep 30, 2024 -117.33 Mn
Jun 30, 2024 -100.62 Mn
Mar 31, 2024 -99.68 Mn
Dec 31, 2023 -197.51 Mn
Sep 30, 2023 -113.54 Mn
Jun 30, 2023 -119.62 Mn
Mar 31, 2023 -134.06 Mn
Dec 31, 2022 -146.12 Mn
Sep 30, 2022 -144.60 Mn
Jun 30, 2022 -130.32 Mn
Mar 31, 2022 -123.34 Mn
Dec 31, 2021 -98.21 Mn
Sep 30, 2021 -107.29 Mn
Jun 30, 2021 -97.64 Mn