Structure Therapeutics (GPCR) Net Cash Flow (2022 - 2026)

Structure Therapeutics (GPCR) recorded quarterly Net Cash Flow of -$483.5 million in Q1 2026, down 169.39% quarter-over-quarter from $696.7 million in Q4 2025, and down 2680.55% on a YoY basis from $18.7 million in Q1 2025.

Structure Therapeutics (GPCR) Net Cash Flow (2022 - 2026) Analysis & Trends

Structure Therapeutics' Net Cash Flow history runs 5 years deep, the most recent figure standing at -$483.5 million for Q1 2026.

  • In Q1 2026, Net Cash Flow fell 2680.55% year-over-year to -$483.5 million; the TTM figure through Mar 2026 stood at $164.0 million (up 202.16% YoY), while the FY2025 annual figure was $630.1 million, up 1486.47% from the prior year.
  • Net Cash Flow was -$483.5 million for Q1 2026 at Structure Therapeutics, down from $696.7 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $696.7 million in Q4 2025 to a low of -$483.5 million in Q1 2026.
  • Historically, Net Cash Flow has averaged $12.4 million across 5 years, with a median of -$5.1 million in 2025.
  • The sharpest annual moves came in 2025 and 2026: Net Cash Flow surged 26692.02% in 2025, then sank 2680.55% in 2026.
  • A 5-year view of Net Cash Flow shows it stood at -$2.0 million in 2022, then surged by 4055.82% to $79.2 million in 2023, then plunged by 103.31% to -$2.6 million in 2024, then soared by 26692.02% to $696.7 million in 2025, then sank by 169.39% to -$483.5 million in 2026.
  • The last three Net Cash Flow figures came in at -$483.5 million (Q1 2026), $696.7 million (Q4 2025), and -$44.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - 2.44 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn 625.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -2.44 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 457.40 Mn
9 Abivax 90.15 Bn 90.15 Bn - 664,983.53
10 Structure Therapeutics 9.35 Bn 9.35 Bn - -483.46 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -483.46 Mn
Mar 31, 2026 -483.46 Mn
Dec 31, 2025 696.71 Mn
Dec 31, 2025 696.71 Mn
Sep 30, 2025 -44.11 Mn
Sep 30, 2025 -44.11 Mn
Jun 30, 2025 -5.10 Mn
Jun 30, 2025 -5.10 Mn
Mar 31, 2025 -17.39 Mn
Mar 31, 2025 -17.39 Mn
Dec 31, 2024 -2.62 Mn
Dec 31, 2024 -2.62 Mn
Sep 30, 2024 -209.50 Mn
Sep 30, 2024 -209.50 Mn
Jun 30, 2024 283.80 Mn
Jun 30, 2024 283.80 Mn
Mar 31, 2024 -31.96 Mn
Mar 31, 2024 -31.96 Mn
Dec 31, 2023 79.16 Mn
Dec 31, 2023 79.16 Mn