Structure Therapeutics (GPCR) Net Cash Flow (2022 - 2026)

Quarterly Net Cash Flow fell 2680.55% to -$483.5 million in Q1 2026 from the year-ago period, while the trailing twelve-month figure was $164.0 million through Mar 2026, up 202.16% year-over-year, with the annual reading at $630.1 million for FY2025, 1486.47% up from the prior year.

Structure Therapeutics' Net Cash Flow history spans 5 years, with the latest figure at -$483.5 million for Q1 2026.

  • Net Cash Flow came in at -$483.5 million for Q1 2026, down from $696.7 million in the prior quarter.
  • In the past five years, Net Cash Flow ranged from a high of $696.7 million in Q4 2025 to a low of -$483.5 million in Q1 2026.
  • The 5-year median for Net Cash Flow is -$5.1 million (2025), against an average of $12.4 million.
  • Year-over-year, Net Cash Flow skyrocketed 26692.02% in 2025 and then plummeted 2680.55% in 2026.
  • Structure Therapeutics' Net Cash Flow stood at -$2.0 million in 2022, then skyrocketed by 4055.82% to $79.2 million in 2023, then plummeted by 103.31% to -$2.6 million in 2024, then surged by 26692.02% to $696.7 million in 2025, then plummeted by 169.39% to -$483.5 million in 2026.
  • Per Business Quant, the three most recent readings for GPCR's Net Cash Flow are -$483.5 million (Q1 2026), $696.7 million (Q4 2025), and -$44.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 2.44 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 625.70 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 457.40 Mn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn -152.20 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 60.68 Mn
10 Structure Therapeutics 8.43 Bn 8.43 Bn - -483.46 Mn

Historic Data

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DateValue
Mar 31, 2026 -483.46 Mn
Mar 31, 2026 -483.46 Mn
Dec 31, 2025 696.71 Mn
Dec 31, 2025 696.71 Mn
Sep 30, 2025 -44.11 Mn
Sep 30, 2025 -44.11 Mn
Jun 30, 2025 -5.10 Mn
Jun 30, 2025 -5.10 Mn
Mar 31, 2025 -17.39 Mn
Mar 31, 2025 -17.39 Mn
Dec 31, 2024 -2.62 Mn
Dec 31, 2024 -2.62 Mn
Sep 30, 2024 -209.50 Mn
Sep 30, 2024 -209.50 Mn
Jun 30, 2024 283.80 Mn
Jun 30, 2024 283.80 Mn
Mar 31, 2024 -31.96 Mn
Mar 31, 2024 -31.96 Mn
Dec 31, 2023 79.16 Mn
Dec 31, 2023 79.16 Mn
Sep 30, 2023 10.05 Mn
Sep 30, 2023 10.05 Mn
Jun 30, 2023 -85.90 Mn
Jun 30, 2023 -85.90 Mn
Mar 31, 2023 100.40 Mn
Mar 31, 2023 100.40 Mn
Dec 31, 2022 -2.00 Mn
Dec 31, 2022 -2.00 Mn
Sep 30, 2022 -27.40 Mn
Sep 30, 2022 -27.40 Mn
Jun 30, 2022 4.87 Mn
Jun 30, 2022 4.87 Mn
Mar 31, 2022 -54.68 Mn
Mar 31, 2022 -54.68 Mn