Structure Therapeutics (GPCR) Net Cash Flow (2022 - 2026)

Structure Therapeutics' (GPCR) quarterly Net Cash Flow came in at -$483.5 million in Q1 2026, down 2680.55% year-on-year from $18.7 million in Q1 2025, and down 169.39% quarter-over-quarter from $696.7 million in Q4 2025.

Structure Therapeutics (GPCR) Net Cash Flow (2022 - 2026) Analysis & Trends

Structure Therapeutics' Net Cash Flow history runs 5 years deep, the most recent figure standing at -$483.5 million for Q1 2026.

  • On a quarterly basis, Net Cash Flow fell 2680.55% year-over-year to -$483.5 million in Q1 2026; TTM through Mar 2026 was $164.0 million, a 202.16% increase from a year earlier, with the FY2025 full-year figure at $630.1 million, up 1486.47% from the prior year.
  • Net Cash Flow slipped to -$483.5 million in Q1 2026 per GPCR's latest filing, from $696.7 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $696.7 million in Q4 2025 and bottomed at -$483.5 million in Q1 2026.
  • The 5-year median for Net Cash Flow is -$5.1 million (2025), against an average of $12.4 million.
  • Across the five-year window, Net Cash Flow jumped 26692.02% in 2025 and sank 2680.55% in 2026, its largest moves.
  • Year by year, Net Cash Flow stood at -$2.0 million in 2022, then surged by 4055.82% to $79.2 million in 2023, then slumped by 103.31% to -$2.6 million in 2024, then soared by 26692.02% to $696.7 million in 2025, then tumbled by 169.39% to -$483.5 million in 2026.
  • Per Business Quant, the three latest GPCR Net Cash Flow figures stand at -$483.5 million (Q1 2026), $696.7 million (Q4 2025), and -$44.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - 10.56 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 224.46 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.34 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 457.40 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -152.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - 57.19 Mn
10 Structure Therapeutics 11.04 Bn 11.04 Bn - -483.46 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -483.46 Mn
Mar 31, 2026 -483.46 Mn
Dec 31, 2025 696.71 Mn
Dec 31, 2025 696.71 Mn
Sep 30, 2025 -44.11 Mn
Sep 30, 2025 -44.11 Mn
Jun 30, 2025 -5.10 Mn
Jun 30, 2025 -5.10 Mn
Mar 31, 2025 -17.39 Mn
Mar 31, 2025 -17.39 Mn
Dec 31, 2024 -2.62 Mn
Dec 31, 2024 -2.62 Mn
Sep 30, 2024 -209.50 Mn
Sep 30, 2024 -209.50 Mn
Jun 30, 2024 283.80 Mn
Jun 30, 2024 283.80 Mn
Mar 31, 2024 -31.96 Mn
Mar 31, 2024 -31.96 Mn
Dec 31, 2023 79.16 Mn
Dec 31, 2023 79.16 Mn