Structure Therapeutics (GPCR) Net Cash Flow (2022 - 2026)

Structure Therapeutics (GPCR) posted quarterly Net Cash Flow of -$483.5 million for Q1 2026, down 2680.55% year-over-year from $18.7 million in Q1 2025, and down 169.39% quarter-over-quarter from $696.7 million in Q4 2025.

Structure Therapeutics (GPCR) Net Cash Flow (2022 - 2026) Analysis & Trends

Structure Therapeutics' Net Cash Flow history runs 5 years deep, the most recent figure standing at -$483.5 million for Q1 2026.

  • In Q1 2026, Net Cash Flow fell 2680.55% year-over-year to -$483.5 million; the TTM figure through Mar 2026 stood at $164.0 million (up 202.16% YoY), while the FY2025 annual figure was $630.1 million, up 1486.47% from the prior year.
  • Net Cash Flow for Q1 2026 stood at -$483.5 million, down from $696.7 million in the prior quarter.
  • The five-year high for Net Cash Flow was $696.7 million in Q4 2025, with the low at -$483.5 million in Q1 2026.
  • The 5-year median for Net Cash Flow is -$5.1 million (2025), against an average of $12.4 million.
  • The sharpest annual moves came in 2025 and 2026: Net Cash Flow jumped 26692.02% in 2025, then plunged 2680.55% in 2026.
  • Structure Therapeutics' Net Cash Flow stood at -$2.0 million in 2022, then jumped by 4055.82% to $79.2 million in 2023, then tumbled by 103.31% to -$2.6 million in 2024, then surged by 26692.02% to $696.7 million in 2025, then plunged by 169.39% to -$483.5 million in 2026.
  • Business Quant data shows GPCR's Net Cash Flow at -$483.5 million in Q1 2026, $696.7 million in Q4 2025, and -$44.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 652.90 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.30 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 407.41 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 17.81 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -496,000.00
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.14 Mn
10 Structure Therapeutics 11.65 Bn 11.65 Bn - -43.53 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -43.53 Mn
Jun 30, 2026 -43.53 Mn
Mar 31, 2026 -483.46 Mn
Mar 31, 2026 -483.46 Mn
Dec 31, 2025 696.71 Mn
Dec 31, 2025 696.71 Mn
Sep 30, 2025 -44.11 Mn
Sep 30, 2025 -44.11 Mn
Jun 30, 2025 -5.10 Mn
Jun 30, 2025 -5.10 Mn
Mar 31, 2025 -17.39 Mn
Mar 31, 2025 -17.39 Mn
Dec 31, 2024 -2.62 Mn
Dec 31, 2024 -2.62 Mn
Sep 30, 2024 -209.50 Mn
Sep 30, 2024 -209.50 Mn
Jun 30, 2024 283.80 Mn
Jun 30, 2024 283.80 Mn
Mar 31, 2024 -31.96 Mn
Mar 31, 2024 -31.96 Mn