Structure Therapeutics (GPCR) Free Cash Flow (2022 - 2026)

Structure Therapeutics' (GPCR) quarterly Free Cash Flow came in at $14.1 million in Q1 2026, up 126.4% year-on-year from $6.2 million in Q1 2025, and up 121.12% quarter-over-quarter from -$66.5 million in Q4 2025.

Structure Therapeutics (GPCR) Free Cash Flow (2022 - 2026) Analysis & Trends

Structure Therapeutics' Free Cash Flow history runs 5 years deep, the most recent figure standing at $14.1 million for Q1 2026.

  • On a quarterly basis, Free Cash Flow rose 126.4% year-over-year to $14.1 million in Q1 2026; TTM through Mar 2026 was -$158.5 million, a 12.57% decrease from a year earlier, with the FY2025 full-year figure at -$225.8 million, down 85.55% from the prior year.
  • Free Cash Flow improved to $14.1 million in Q1 2026 per GPCR's latest filing, from -$66.5 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at $14.1 million in Q1 2026 and bottomed at -$66.5 million in Q4 2025.
  • The 5-year median for Free Cash Flow is -$20.9 million (2023), against an average of -$27.0 million.
  • Across the five-year window, Free Cash Flow sank 154.86% in 2025 and soared 126.4% in 2026, its largest moves.
  • Year by year, Free Cash Flow stood at -$12.0 million in 2022, then tumbled by 78.85% to -$21.5 million in 2023, then plunged by 87.53% to -$40.3 million in 2024, then sank by 65.29% to -$66.5 million in 2025, then surged by 121.12% to $14.1 million in 2026.
  • Per Business Quant, the three latest GPCR Free Cash Flow figures stand at $14.1 million (Q1 2026), -$66.5 million (Q4 2025), and -$51.9 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Structure Therapeutics 11.04 Bn 11.04 Bn - 14.05 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 14.05 Mn
Mar 31, 2026 14.05 Mn
Dec 31, 2025 -66.54 Mn
Dec 31, 2025 -66.54 Mn
Sep 30, 2025 -51.94 Mn
Sep 30, 2025 -51.94 Mn
Jun 30, 2025 -54.11 Mn
Jun 30, 2025 -54.11 Mn
Mar 31, 2025 -53.22 Mn
Mar 31, 2025 -53.22 Mn
Dec 31, 2024 -40.25 Mn
Dec 31, 2024 -40.25 Mn
Sep 30, 2024 -20.38 Mn
Sep 30, 2024 -20.38 Mn
Jun 30, 2024 -26.98 Mn
Jun 30, 2024 -26.98 Mn
Mar 31, 2024 -34.08 Mn
Mar 31, 2024 -34.08 Mn
Dec 31, 2023 -21.47 Mn
Dec 31, 2023 -21.47 Mn