Structure Therapeutics (GPCR) Change in Cash (2022 - 2026)

Structure Therapeutics' (GPCR) quarterly Change in Cash came in at -$483.5 million in Q1 2026, down 2680.55% year-on-year from $18.7 million in Q1 2025, and down 169.39% quarter-over-quarter from $696.7 million in Q4 2025.

Structure Therapeutics (GPCR) Change in Cash (2022 - 2026) Analysis & Trends

Structure Therapeutics' Change in Cash history runs 5 years deep, the most recent figure standing at -$483.5 million for Q1 2026.

  • On a quarterly basis, Change in Cash fell 2680.55% year-over-year to -$483.5 million in Q1 2026; TTM through Mar 2026 was $164.0 million, a 202.16% increase from a year earlier, with the FY2025 full-year figure at $630.1 million, up 1486.47% from the prior year.
  • Change in Cash slipped to -$483.5 million in Q1 2026 per GPCR's latest filing, from $696.7 million in the prior quarter.
  • Across five years, Change in Cash topped out at $696.7 million in Q4 2025 and bottomed at -$483.5 million in Q1 2026.
  • The 5-year median for Change in Cash is -$5.1 million (2025), against an average of $12.4 million.
  • Across the five-year window, Change in Cash jumped 26692.02% in 2025 and sank 2680.55% in 2026, its largest moves.
  • Year by year, Change in Cash stood at -$2.0 million in 2022, then surged by 4055.82% to $79.2 million in 2023, then slumped by 103.31% to -$2.6 million in 2024, then soared by 26692.02% to $696.7 million in 2025, then tumbled by 169.39% to -$483.5 million in 2026.
  • Per Business Quant, the three latest GPCR Change in Cash figures stand at -$483.5 million (Q1 2026), $696.7 million (Q4 2025), and -$44.1 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -22.03 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 243.78 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.34 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 417.10 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -153.10 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - 57.19 Mn
10 Structure Therapeutics 11.04 Bn 11.04 Bn - -483.46 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -483.46 Mn
Dec 31, 2025 696.71 Mn
Sep 30, 2025 -44.11 Mn
Jun 30, 2025 -5.10 Mn
Mar 31, 2025 -17.39 Mn
Dec 31, 2024 -2.62 Mn
Sep 30, 2024 -209.50 Mn
Jun 30, 2024 283.80 Mn
Mar 31, 2024 -31.96 Mn
Dec 31, 2023 79.16 Mn
Sep 30, 2023 10.05 Mn
Jun 30, 2023 -85.90 Mn
Mar 31, 2023 100.40 Mn
Dec 31, 2022 -2.00 Mn
Sep 30, 2022 -27.40 Mn
Jun 30, 2022 4.87 Mn
Mar 31, 2022 -54.68 Mn