Structure Therapeutics (GPCR) Change in Cash (2022 - 2026)
Structure Therapeutics (GPCR) posted quarterly Change in Cash of -$483.5 million for Q1 2026, down 2680.55% year-over-year from $18.7 million in Q1 2025, and down 169.39% quarter-over-quarter from $696.7 million in Q4 2025.
Analysis
Structure Therapeutics (GPCR) Change in Cash (2022 - 2026) Analysis & Trends
Structure Therapeutics' Change in Cash history runs 5 years deep, the most recent figure standing at -$483.5 million for Q1 2026.
- In Q1 2026, Change in Cash fell 2680.55% year-over-year to -$483.5 million; the TTM figure through Mar 2026 stood at $164.0 million (up 202.16% YoY), while the FY2025 annual figure was $630.1 million, up 1486.47% from the prior year.
- Change in Cash for Q1 2026 stood at -$483.5 million, down from $696.7 million in the prior quarter.
- The five-year high for Change in Cash was $696.7 million in Q4 2025, with the low at -$483.5 million in Q1 2026.
- The 5-year median for Change in Cash is -$5.1 million (2025), against an average of $12.4 million.
- The sharpest annual moves came in 2025 and 2026: Change in Cash jumped 26692.02% in 2025, then plunged 2680.55% in 2026.
- Structure Therapeutics' Change in Cash stood at -$2.0 million in 2022, then jumped by 4055.82% to $79.2 million in 2023, then tumbled by 103.31% to -$2.6 million in 2024, then surged by 26692.02% to $696.7 million in 2025, then plunged by 169.39% to -$483.5 million in 2026.
- Business Quant data shows GPCR's Change in Cash at -$483.5 million in Q1 2026, $696.7 million in Q4 2025, and -$44.1 million in Q3 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 649.20 Mn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | -504.60 Mn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | - |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -185.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | 374.50 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 427.25 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | -2.94 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 225.59 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -37.42 Mn |
| 10 | Structure Therapeutics | 10.32 Bn | 10.32 Bn | - | -43.53 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -43.53 Mn |
| Mar 31, 2026 | -483.46 Mn |
| Dec 31, 2025 | 696.71 Mn |
| Sep 30, 2025 | -44.11 Mn |
| Jun 30, 2025 | -5.10 Mn |
| Mar 31, 2025 | -17.39 Mn |
| Dec 31, 2024 | -2.62 Mn |
| Sep 30, 2024 | -209.50 Mn |
| Jun 30, 2024 | 283.80 Mn |
| Mar 31, 2024 | -31.96 Mn |
| Dec 31, 2023 | 79.16 Mn |
| Sep 30, 2023 | 10.05 Mn |
| Jun 30, 2023 | -85.90 Mn |
| Mar 31, 2023 | 100.40 Mn |
| Dec 31, 2022 | -2.00 Mn |
| Sep 30, 2022 | -27.40 Mn |
| Jun 30, 2022 | 4.87 Mn |
| Mar 31, 2022 | -54.68 Mn |