Fulcrum Therapeutics (FULC) Return on Sales (2020 - 2025)

Fulcrum Therapeutics (FULC) posted quarterly Return on Sales of 0.02% for Q2 2025, down 2.0% year-over-year from 0.02% in Q2 2024, and down 54.75% quarter-over-quarter from 0.01% in Q4 2024.

Fulcrum Therapeutics (FULC) Return on Sales (2020 - 2025) Analysis & Trends

Fulcrum Therapeutics (FULC) has reported Return on Sales for 6 consecutive years, with 0.02% the latest figure, recorded in Q2 2025.

  • In Q2 2025, Return on Sales fell 2.0% year-over-year to 0.02%; the TTM figure through Jun 2025 stood at 0.02% (changed 0.0% YoY), while the FY2024 annual figure was 0.01%, up 97.0% from the prior year.
  • Return on Sales declined to 0.02% in Q2 2025 per FULC's latest filing, from 0.01% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.01% in Q2 2024 and bottomed at 1.42% in Q1 2023.
  • Historically, Return on Sales has averaged 0.34% across 5 years, with a median of 0.27% in 2022.
  • Annual changes were most pronounced in 2023 — Return on Sales plunged 106 bps — and 2024, when it surged 66 bps.
  • Fulcrum Therapeutics' Return on Sales stood at 0.23% in 2021, then sank by 86 bps to 0.44% in 2022, then retreated by 14 bps to 0.49% in 2023, then surged by 98 bps to 0.01% in 2024, then tumbled by 55 bps to 0.02% in 2025.
  • Business Quant data shows FULC's Return on Sales at 0.02% in Q2 2025, 0.01% in Q4 2024, and 0.01% in Q3 2024.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Fulcrum Therapeutics 285.31 Mn 285.31 Mn - -

Historic Data

Download Data
DateValue
Jun 30, 2025 -0.02%
Dec 31, 2024 -0.01%
Sep 30, 2024 -0.01%
Jun 30, 2024 0.01%
Mar 31, 2024 -0.71%
Dec 31, 2023 -0.49%
Sep 30, 2023 -0.53%
Jun 30, 2023 -0.35%
Mar 31, 2023 -1.03%
Dec 31, 2022 -2.81%
Sep 30, 2022 -0.23%
Jun 30, 2022 -0.19%
Mar 31, 2022 -0.36%
Dec 31, 2021 -0.10%
Sep 30, 2021 -0.20%
Jun 30, 2021 -0.09%
Mar 31, 2021 -0.05%
Dec 31, 2020 -0.04%
Sep 30, 2020 -0.21%
Jun 30, 2020 -0.17%