Fulcrum Therapeutics, Inc. (FULC) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

0Shares Outstanding

17,188,141Shares held by institutions

$112,754,205Value of institutional holdings

87.35%Institutional ownership %

4.66%Shares Changed QoQ

120No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Fulcrum Therapeutics, Inc. (NASDAQ:FULC) appears in 168 institutional 13F filings for the quarter ending December 2025.

Their combined ownership stood at 109.8% of outstanding shares in December 2025, up from 86.3% in September 2025.
They increased total shares held in FULC by 29.11% quarter over quarter, and investors in Fulcrum Therapeutics increased 41.18% from a year ago.
Of these 168 holders, 100 added to their stakes in Fulcrum Therapeutics, 50 trimmed positions, and 18 made no changes.
The aggregate institutional position in Fulcrum Therapeutics amounted to 68.72Mn shares as of December 2025, up by 15.49Mn shares quarter on quarter, and up 15.06Mn shares year over year.
As of December 31, 2025, the biggest holder of Fulcrum Therapeutics is SUVRETTA CAPITAL MANAGEMENT, LLC at 6.56Mn shares, representing 10.48% of shares outstanding.
The biggest buyers of Fulcrum Therapeutics for the quarter ending December 2025 included BRAIDWELL LP (2.84Mn), Point72 Asset Management, L.P. (2.4Mn), ADAR1 Capital Management, LLC (2.17Mn), Siren, L.L.C. (1.95Mn), First Turn Management, LLC (1.89Mn).
The biggest sellers of Fulcrum Therapeutics for the quarter ending December 2025 included RA CAPITAL MANAGEMENT, L.P. (4.18Mn), Royal Bank Of Canada (996.74K), ADAGE CAPITAL PARTNERS GP, L.L.C. (732.0K), BALYASNY ASSET MANAGEMENT L.P. (480.04K), Nantahala Capital Management, LLC (377.44K).
According to Business Quant data, leading holders of FULC for December 2025 are SUVRETTA CAPITAL MANAGEMENT, LLC (6.56Mn), RA CAPITAL MANAGEMENT, L.P. (6.05Mn), TCG Crossover Management, LLC (5.25Mn), Nantahala Capital Management, LLC (4.29Mn), BlackRock, Inc. (4.26Mn), VANGUARD GROUP INC (3.56Mn), BRAIDWELL LP (3.06Mn), ADAR1 Capital Management, LLC (2.51Mn), Point72 Asset Management, L.P. (2.4Mn), Siren, L.L.C. (1.95Mn).

168 Institutional Holders

17,188,141 Total Shares Held

Rows:

Download Data

Owner Name	Date	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	557,011	15.03%	$0.00
SUVRETTA CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,180,111	21.93%	$0.00
TCG Crossover Management, LLC	31 Dec, 2025	0	0.00%	$0.00
Barclays Plc	31 Dec, 2025	-81,216	-37.99%	$0.00
RA CAPITAL MANAGEMENT, L.P.	31 Dec, 2025	-4,175,139	-40.82%	$0.00
BRAIDWELL LP	31 Dec, 2025	2,841,734	1,294.71%	$0.00
HSBC HOLDINGS PLC	31 Dec, 2025	32,718	60.81%	$0.00
Nantahala Capital Management, LLC	31 Dec, 2025	-377,438	-8.08%	$0.00
ADAR1 Capital Management, LLC	31 Dec, 2025	2,165,886	634.02%	$0.00
Rockefeller Capital Management L.P.	31 Dec, 2025	448	0.00%	$0.00
VANGUARD GROUP INC	31 Dec, 2025	560,088	18.67%	$0.00
Point72 Asset Management, L.P.	31 Dec, 2025	2,398,232	0.00%	$0.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	464,332	32.04%	$0.00
Siren, L.L.C.	31 Dec, 2025	1,950,000	0.00%	$0.00
GSK plc	31 Dec, 2025	1,785,714	0.00%	$0.00
First Turn Management, LLC	31 Dec, 2025	1,892,683	0.00%	$0.00
ADAGE CAPITAL PARTNERS GP, L.L.C.	31 Dec, 2025	-732,000	-30.10%	$0.00
Ikarian Capital, LLC	31 Dec, 2025	86,247	6.69%	$0.00
CITADEL ADVISORS LLC	31 Dec, 2025	352,448	41.24%	$0.00
Aberdeen Group plc	31 Dec, 2025	1,116,066	808.97%	$0.00

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