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Exelixis (EXEL) Operating Margin: 2010-2025

Historic Operating Margin for Exelixis (EXEL) over the last 16 years, with Oct 2025 value amounting to 39.57%.

  • Exelixis' Operating Margin rose 1435.00% to 39.57% in Q4 2025 from the same period last year, while for Oct 2025 it was 34.97%, marking a year-over-year increase of 984.00%. This contributed to the annual value of 27.88% for FY2025, which is 1854.00% up from last year.
  • Per Exelixis' latest filing, its Operating Margin stood at 39.57% for Q4 2025, which was up 5.29% from 37.58% recorded in Q3 2025.
  • In the past 5 years, Exelixis' Operating Margin registered a high of 43.30% during Q2 2024, and its lowest value of -11.34% during Q4 2022.
  • Over the past 3 years, Exelixis' median Operating Margin value was 25.22% (recorded in 2024), while the average stood at 22.91%.
  • Data for Exelixis' Operating Margin shows a peak YoY increase of 3,414bps (in 2021) and a maximum YoY decrease of 2,498bps (in 2021) over the last 5 years.
  • Quarterly analysis of 5 years shows Exelixis' Operating Margin stood at 15.72% in 2021, then soared by 435bps to -11.34% in 2022, then soared by 2,839bps to 17.05% in 2023, then skyrocketed by 2,895bps to 25.22% in 2024, then surged by 1,435bps to 39.57% in 2025.
  • Its Operating Margin was 39.57% in Q4 2025, compared to 37.58% in Q3 2025 and 33.64% in Q2 2025.