Exelixis (EXEL) Operating Income (2010 - 2026)

Exelixis' (EXEL) quarterly Operating Income came in at $251.3 million in Q2 2026, up 34.51% year-on-year from $186.9 million in Q2 2025, and up 6.86% quarter-over-quarter from $235.2 million in Q1 2026.

Exelixis (EXEL) Operating Income (2010 - 2026) Analysis & Trends

Exelixis' Operating Income history runs 17 years deep, the most recent figure standing at $251.3 million for Q2 2026.

  • On a quarterly basis, Operating Income rose 34.51% year-over-year to $251.3 million in Q2 2026; TTM through Apr 2026 was $936.7 million, a 22.92% increase from a year earlier, with the FY2026 full-year figure at $872.2 million, up 44.26% from the prior year.
  • Operating Income improved to $251.3 million in Q2 2026 per EXEL's latest filing, from $235.2 million in the prior quarter.
  • Across five years, Operating Income topped out at $275.9 million in Q2 2024 and bottomed at -$48.1 million in Q4 2022.
  • The 5-year median for Operating Income is $83.7 million (2022), against an average of $123.6 million.
  • Across the five-year window, Operating Income soared 1906.88% in 2022 and tumbled 121.28% in 2023, its largest moves.
  • Year by year, Operating Income stood at -$48.1 million in 2022, then soared by 270.12% to $81.8 million in 2023, then surged by 66.38% to $136.1 million in 2024, then soared by 73.83% to $236.5 million in 2025, then increased by 6.26% to $251.3 million in 2026.
  • Per Business Quant, the three latest EXEL Operating Income figures stand at $251.3 million (Q2 2026), $235.2 million (Q1 2026), and $236.5 million (Q4 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -27.75 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 249.90 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.72 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -32.68 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 493.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -445.22 Mn
10 Exelixis 14.38 Bn 13.60 Bn 590.86 Mn 251.34 Mn

Historic Data

Download Data
DateValue
Apr 3, 2026 251.34 Mn
Jan 2, 2026 235.22 Mn
Oct 3, 2025 236.54 Mn
Jul 4, 2025 213.58 Mn
Apr 4, 2025 186.86 Mn
Jan 3, 2025 163.21 Mn
Sep 27, 2024 136.08 Mn
Jun 28, 2024 275.87 Mn
Mar 29, 2024 29.46 Mn
Dec 29, 2023 81.79 Mn
Sep 29, 2023 -17.58 Mn
Jun 30, 2023 77.85 Mn
Mar 31, 2023 28.83 Mn
Dec 30, 2022 -48.08 Mn
Sep 30, 2022 82.61 Mn
Jul 1, 2022 83.71 Mn
Apr 1, 2022 83.24 Mn
Oct 1, 2021 51.62 Mn
Jul 2, 2021 123.01 Mn
Apr 2, 2021 -4.61 Mn