Cyclerion Therapeutics (CYCN) Return on Sales (2019 - 2025)

Cyclerion Therapeutics' Return on Sales history runs 6 years deep, the most recent figure standing at 0.01% for Q3 2025.

• In Q3 2025, Return on Sales changed N/A year-over-year to 0.01%; the TTM figure through Sep 2025 stood at 0.01% (changed N/A YoY), while the FY2022 annual figure was 0.87%, down 73.0% from the prior year.
• Return on Sales was 0.01% for Q3 2025 at Cyclerion Therapeutics, up from 0.18% in the prior quarter.
• In the past five years, Return on Sales ranged from a high of 0.01% in Q3 2025 to a low of 2.16% in Q1 2021.
• Historically, Return on Sales has averaged 0.44% across 4 years, with a median of 0.29% in 2021.
• The sharpest annual moves came in 2021 and 2022: Return on Sales tumbled 196 bps in 2021, then soared 198 bps in 2022.
• A 4-year view of Return on Sales shows it stood at 0.27% in 2021, then slipped by 29 bps to 0.35% in 2022, then slumped by 146 bps to 0.86% in 2023, then surged by 99 bps to 0.01% in 2025.
• The last three Return on Sales figures came in at 0.01% (Q3 2025), 0.18% (Q2 2025), and 0.18% (Q1 2025), per Business Quant data.