Cyclerion Therapeutics (CYCN) Return on Capital Employed (2019 - 2025)

Cyclerion Therapeutics (CYCN) recorded quarterly Return on Capital Employed of 40.3% in Q3 2025, up 5.47% quarter-over-quarter from 42.63% in Q2 2025, and up 2717.0% on a YoY basis from 1.43% in Q3 2024.

Cyclerion Therapeutics (CYCN) Return on Capital Employed (2019 - 2025) Analysis & Trends

Cyclerion Therapeutics' Return on Capital Employed history runs 7 years deep, the most recent figure standing at 40.3% for Q3 2025.

  • In Q3 2025, Return on Capital Employed rose 2717.0% year-over-year to 40.3%; the TTM figure through Sep 2025 stood at 40.3% (up 2717.0% YoY), while the FY2024 annual figure was 33.75%, up 6119.0% from the prior year.
  • Return on Capital Employed was 40.3% for Q3 2025 at Cyclerion Therapeutics, up from 42.63% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 40.11% in Q1 2025 to a low of 354.88% in Q1 2023.
  • Historically, Return on Capital Employed has averaged 128.29% across 5 years, with a median of 105.23% in 2021.
  • The sharpest annual moves came in 2023 and 2024: Return on Capital Employed tumbled 22876 bps in 2023, then jumped 25154 bps in 2024.
  • A 5-year view of Return on Capital Employed shows it stood at 105.23% in 2021, then plunged by 141 bps to 253.89% in 2022, then jumped by 58 bps to 106.08% in 2023, then surged by 60 bps to 42.62% in 2024, then grew by 5 bps to 40.3% in 2025.
  • The last three Return on Capital Employed figures came in at 40.3% (Q3 2025), 42.63% (Q2 2025), and 40.11% (Q1 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 719,706.53 Bn 719,706.50 Bn - -
2 Belite Bio 55,800.00 Bn 55,800.00 Bn - -
3 Quantum Biopharma 18,182.30 Bn 18,182.29 Bn - 450.31%
4 Legend Biotech 3,154.00 Bn 3,153.71 Bn 242.10 Mn 51.73%
5 Akari Therapeutics 1,844.30 Bn 1,844.29 Bn - -107.40%
6 Evaxion A 1,567.96 Bn 1,567.94 Bn - -
7 Psyence Biomedical 251.43 Bn 251.42 Bn - -
8 Vertex Pharmaceuticals 112.56 Bn 105.31 Bn 2.59 Bn 21.10%
9 Abivax 94.37 Bn 94.37 Bn - -50.43%
10 Cyclerion Therapeutics 11.50 Mn 8.26 Mn - -

Historic Data

Download Data
DateValue
Sep 30, 2025 -40.30%
Jun 30, 2025 -42.63%
Mar 31, 2025 -40.11%
Dec 31, 2024 -42.62%
Sep 30, 2024 -67.47%
Jun 30, 2024 -114.62%
Mar 31, 2024 -103.34%
Dec 31, 2023 -106.08%
Sep 30, 2023 -151.34%
Jun 30, 2023 -242.10%
Mar 31, 2023 -354.88%
Dec 31, 2022 -253.89%
Sep 30, 2022 -209.56%
Jun 30, 2022 -167.78%
Mar 31, 2022 -126.12%
Dec 31, 2021 -105.23%
Sep 30, 2021 -99.50%
Jun 30, 2021 -91.25%
Mar 31, 2021 -78.63%
Dec 31, 2020 -76.35%