Cue Biopharma (CUE) Return on Sales (2018 - 2025)

Cue Biopharma has disclosed Return on Sales across 8 years of filings, most recently posting 0.02% for Q4 2025.

• Return on Sales for Q4 2025 came in at 0.02%, down 13.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 0.0% (changed 0.0% YoY), and the FY2025 annual result was 0.0%, up 1.0% from the prior year.
• Return on Sales came in at 0.02% for Q4 2025 at Cue Biopharma, up from 0.03% in the prior quarter.
• In the past five years, Return on Sales ranged from a high of 0.15% in Q4 2024 to a low of 5.08% in Q2 2022.
• The 5-year median for Return on Sales is 0.06% (2024), against an average of 0.46%.
• Across the five-year window, Return on Sales plunged 504 bps in 2022 and jumped 499 bps in 2023, its largest moves.
• Cue Biopharma's Return on Sales stood at 0.01% in 2021, then slumped by 9763 bps to 0.94% in 2022, then jumped by 92 bps to 0.07% in 2023, then surged by 311 bps to 0.15% in 2024, then plunged by 84 bps to 0.02% in 2025.
• The last three Return on Sales figures came in at 0.02% (Q4 2025), 0.03% (Q3 2025), and 0.03% (Q2 2025), per Business Quant data.