Cue Biopharma (CUE) Return on Capital Employed (2018 - 2025)
Cue Biopharma's (CUE) quarterly Return on Capital Employed came in at 23.38% in Q4 2025, up 1103.0% year-on-year from 1.94% in Q4 2024, and up 7.18% quarter-over-quarter from 25.19% in Q3 2025.
Cue Biopharma (CUE) Return on Capital Employed (2018 - 2025) Analysis & Trends
Cue Biopharma has disclosed Return on Capital Employed across 8 years of filings, most recently posting 23.38% for Q4 2025.
- Return on Capital Employed for Q4 2025 came in at 23.38%, up 1103.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 23.38% (up 1103.0% YoY), and the FY2025 annual result was 23.12%, up 263.0% from the prior year.
- Return on Capital Employed came in at 23.38% for Q4 2025 at Cue Biopharma, up from 25.19% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 23.38% in Q4 2025 to a low of 170.65% in Q3 2024.
- The 5-year median for Return on Capital Employed is 66.86% (2021), against an average of 76.7%.
- Across the five-year window, Return on Capital Employed plunged 7183 bps in 2024 and surged 14545 bps in 2025, its largest moves.
- Cue Biopharma's Return on Capital Employed stood at 63.98% in 2021, then decreased by 15 bps to 73.67% in 2022, then plunged by 47 bps to 108.35% in 2023, then surged by 68 bps to 34.42% in 2024, then soared by 32 bps to 23.38% in 2025.
- The last three Return on Capital Employed figures came in at 23.38% (Q4 2025), 25.19% (Q3 2025), and 52.53% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 450.31% |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 51.73% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -107.40% |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -50.43% |
| 10 | Cue Biopharma | 581.16 Mn | 553.47 Mn | - | -23.38% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -23.38% |
| Sep 30, 2025 | -25.19% |
| Jun 30, 2025 | -52.53% |
| Mar 31, 2025 | -69.69% |
| Dec 31, 2024 | -34.42% |
| Sep 30, 2024 | -170.65% |
| Jun 30, 2024 | -152.46% |
| Mar 31, 2024 | -129.72% |
| Dec 31, 2023 | -108.35% |
| Sep 30, 2023 | -98.82% |
| Jun 30, 2023 | -86.38% |
| Mar 31, 2023 | -72.06% |
| Dec 31, 2022 | -73.67% |
| Sep 30, 2022 | -65.79% |
| Jun 30, 2022 | -60.75% |
| Mar 31, 2022 | -60.09% |
| Dec 31, 2021 | -63.98% |
| Sep 30, 2021 | -67.93% |
| Jun 30, 2021 | -60.57% |
| Mar 31, 2021 | -57.51% |