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Guardant Health (GH) Gross Profit (2017 - 2025)

Guardant Health's Gross Profit history spans 8 years, with the latest figure at $283.5 million for Q4 2025.

  • For Q4 2025, Gross Profit rose 192.15% year-over-year to $283.5 million; the TTM value through Dec 2025 reached $633.0 million, up 69.22%, while the annual FY2025 figure was $633.0 million, 69.22% up from the prior year.
  • Gross Profit for Q4 2025 was $283.5 million at Guardant Health, up from $137.8 million in the prior quarter.
  • Across five years, Gross Profit topped out at $345.3 million in Q4 2022 and bottomed at $31.7 million in Q1 2022.
  • The 5-year median for Gross Profit is $82.0 million (2023), against an average of $105.0 million.
  • The largest annual shift saw Gross Profit soared 411.16% in 2021 before it tumbled 78.01% in 2023.
  • A 5-year view of Gross Profit shows it stood at $240.4 million in 2021, then surged by 43.64% to $345.3 million in 2022, then crashed by 78.01% to $75.9 million in 2023, then grew by 27.82% to $97.1 million in 2024, then surged by 192.15% to $283.5 million in 2025.
  • Per Business Quant, the three most recent readings for GH's Gross Profit are $283.5 million (Q4 2025), $137.8 million (Q3 2025), and $112.5 million (Q2 2025).