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Guardant Health (GH) Gross Profit (2025)

Guardant Health (GH) has disclosed Gross Profit for 9 consecutive years, with $181.8 million as the latest value for Q4 2025.

  • Quarterly Gross Profit rose 87.3% to $181.8 million in Q4 2025 from the year-ago period, while the trailing twelve-month figure was $560.8 million through Dec 2025, up 41.1% year-over-year, with the annual reading at $633.0 million for FY2025, 69.22% up from the prior year.
  • Gross Profit hit $181.8 million in Q4 2025 for Guardant Health, up from $137.8 million in the prior quarter.
  • In the past five years, Gross Profit ranged from a high of $287.8 million in Q4 2023 to a low of $31.7 million in Q1 2022.
  • Historically, Gross Profit has averaged $98.1 million across 5 years, with a median of $81.1 million in 2023.
  • Biggest five-year swings in Gross Profit: plummeted 81.09% in 2022 and later skyrocketed 532.87% in 2023.
  • Year by year, Gross Profit stood at $240.4 million in 2021, then tumbled by 81.09% to $45.5 million in 2022, then surged by 532.87% to $287.8 million in 2023, then plummeted by 66.27% to $97.1 million in 2024, then soared by 87.3% to $181.8 million in 2025.
  • Business Quant data shows Gross Profit for GH at $181.8 million in Q4 2025, $137.8 million in Q3 2025, and $112.5 million in Q2 2025.