CRISPR Therapeutics AG (CRSP) Return on Capital Employed (2016 - 2026)

CRISPR Therapeutics AG (CRSP) posted Return on Capital Employed of 27.4% for Q1 2026, up 13.17% sequentially from 31.55% in Q4 2025, and down 464.0% YoY from 7.53% in Q1 2025.

CRISPR Therapeutics AG (CRSP) Return on Capital Employed (2016 - 2026) Analysis & Trends

CRISPR Therapeutics AG has reported Return on Capital Employed for 11 years, with the latest figure at 27.4% in Q1 2026.

  • Quarterly Return on Capital Employed fell 464.0% year-over-year to 27.4% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 27.4% (down 464.0% YoY) and the FY2025 annual result came in at 31.58%, down 986.0% from the prior year.
  • Return on Capital Employed improved to 27.4% in Q1 2026 per CRSP's latest filing, from 31.55% in the prior quarter.
  • Over five years, Return on Capital Employed peaked at 12.17% in Q1 2022 and troughed at 31.55% in Q4 2025.
  • A 5-year average of 21.2% and a median of 22.76% in 2025 frame the typical range for Return on Capital Employed.
  • The widest YoY moves for Return on Capital Employed: up 3401 bps in 2022, down 4548 bps in 2022.
  • Over 5 years, Return on Capital Employed stood at 30.92% in 2022, then soared by 65 bps to 10.86% in 2023, then slumped by 99 bps to 21.59% in 2024, then slumped by 46 bps to 31.55% in 2025, then grew by 13 bps to 27.4% in 2026.
  • According to Business Quant data, Return on Capital Employed over the past three periods registered 27.4%, 31.55%, and 28.46% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 10.74%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -55.45%
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 13.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -0.20%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 7.88%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 26.09%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -50.93%
10 CRISPR Therapeutics AG 5.18 Bn 5.18 Bn - -20.91%

Historic Data

Download Data
DateValue
Jun 30, 2026 -20.91%
Mar 31, 2026 -27.40%
Dec 31, 2025 -31.55%
Sep 30, 2025 -28.46%
Jun 30, 2025 -27.71%
Mar 31, 2025 -22.76%
Dec 31, 2024 -21.59%
Sep 30, 2024 -15.05%
Jun 30, 2024 -15.68%
Mar 31, 2024 -13.48%
Dec 31, 2023 -10.86%
Sep 30, 2023 -20.86%
Jun 30, 2023 -22.69%
Mar 31, 2023 -26.79%
Dec 31, 2022 -30.92%
Sep 30, 2022 -30.45%
Jun 30, 2022 -26.25%
Mar 31, 2022 12.17%
Dec 31, 2021 14.01%
Sep 30, 2021 14.88%