CRISPR Therapeutics AG (CRSP) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

96,750,370Shares Outstanding

5,048,730Shares held by institutions

$268,440,974Value of institutional holdings

79.05%Institutional ownership %

5.67%Shares Changed QoQ

451No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

According to SEC filings for the period ending December 2025, CRISPR Therapeutics AG (NASDAQ:CRSP) is held by 451 institutional firms.

These investors collectively held 79.0% of the company's total shares outstanding in December 2025, down from 81.0% in September 2025.
In percentage terms, this reflects as a holdings change of 5.67% quarter on quarter, and an increase of 13.89% year over year.
During the quarter, 233 institutions bought more CRISPR Therapeutics AG shares, 119 sold shares, and 99 of the 451 total investors held their position steady.
Collectively, institutional investors increased their stake in CRISPR Therapeutics AG to 76.48Mn shares as of December 2025, a change that is up by 4.10Mn shares quarter on quarter and up 11.55Mn shares year over year.
The top institutional stake in CRISPR Therapeutics AG as of December 31, 2025 belongs to ARK Investment Management LLC, which owns 10.52Mn shares, or 10.88% of the company.
Among the most significant buyers of CRISPR Therapeutics AG during December 2025 were GSK plc (3.22Mn), Orbis Allan Gray Ltd (968.06K), ARK Investment Management LLC (735.08K), Squarepoint Ops LLC (530.11K), NORGES BANK (490.21K).
Leading sellers of CRISPR Therapeutics AG stock in December 2025 included T. Rowe Price Investment Management, Inc. (1.44Mn), MORGAN STANLEY (730.80K), TWO SIGMA INVESTMENTS, LP (574.07K), TWO SIGMA ADVISERS, LP (410.57K), ROYAL BANK OF CANADA (300.61K).
The top 10 institutional holders of CRISPR Therapeutics AG for the quarter ending December 2025 included ARK Investment Management LLC (10.52Mn), BlackRock, Inc. (7.51Mn), Orbis Allan Gray Ltd (5.95Mn), Capital International Investors (5.89Mn), STATE STREET CORP (3.75Mn), GSK plc (3.22Mn), UBS Group AG (2.52Mn), VANGUARD GROUP INC (2.27Mn), GEODE CAPITAL MANAGEMENT, LLC (2.25Mn), SR ONE CAPITAL MANAGEMENT, LP (2.04Mn).

451 Institutional Holders

5,048,730 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
ARK Investment Management LLC	31 Dec, 2025	10,522,057	735,084	7.51%	$551,776,677.00
BlackRock, Inc.	31 Dec, 2025	7,508,178	458,033	6.50%	$393,728,856.00
Orbis Allan Gray Ltd	31 Dec, 2025	5,950,145	968,060	19.43%	$312,025,603.00
Capital International Investors	31 Dec, 2025	5,892,745	243,487	4.31%	$309,015,548.00
STATE STREET CORP	31 Dec, 2025	3,753,440	-253,793	-6.33%	$196,830,394.00
GSK plc	31 Dec, 2025	3,220,627	3,220,627	0.00%	$168,889,680.00
UBS Group AG	31 Dec, 2025	2,524,144	185,088	7.91%	$132,366,111.00
VANGUARD GROUP INC	31 Dec, 2025	2,268,394	-96,251	-4.07%	$118,954,581.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	2,249,223	108,053	5.05%	$117,970,852.00
SR ONE CAPITAL MANAGEMENT, LP	31 Dec, 2025	2,038,763	0	0.00%	$106,912,732.00
Sumitomo Mitsui Trust Group, Inc.	31 Dec, 2025	1,958,111	-205,564	-9.50%	$102,683,341.00
Amova Asset Management Americas, Inc.	31 Dec, 2025	1,958,111	-205,564	-9.50%	$102,605,016.00
FMR LLC	31 Dec, 2025	1,953,957	68,294	3.62%	$102,465,517.00
T. Rowe Price Investment Management, Inc.	31 Dec, 2025	1,845,364	-1,437,220	-43.78%	$96,771.00
EcoR1 Capital, LLC	31 Dec, 2025	1,389,276	0	0.00%	$72,853,633.00
BANK OF AMERICA CORP /DE/	31 Dec, 2025	1,096,887	-27,232	-2.42%	$57,520,761.00
NEA Management Company, LLC	31 Dec, 2025	1,058,570	0	0.00%	$55,511,411.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	1,030,182	44,412	4.51%	$54,022,744.00
DIMENSIONAL FUND ADVISORS LP	31 Dec, 2025	907,107	30,078	3.43%	$47,572,612.00
JANE STREET GROUP, LLC	31 Dec, 2025	904,600	377,600	71.65%	$47,437,224.00

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