Crinetics Pharmaceuticals (CRNX) Net Margin (2017 - 2026)
Crinetics Pharmaceuticals' Net Margin came in at -481.15% for Q2 2026, up 10734.85 percentage points from -11216.00% a year earlier and up 709.88 percentage points from the prior quarter.
Crinetics Pharmaceuticals (CRNX) Net Margin (2017 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Crinetics Pharmaceuticals reported Net Margin of -1189.88%, up 25378.65 percentage points year-over-year; for FY2025, it came in at -6046.22%, up 22674.47 percentage points from FY2024.
- Net Margin carries a five-year change of +97914.34 percentage points (FY2020 to FY2025).
- Going back by year, Net Margin was -28720.69% in FY2024 (-23374.84 pp), -5345.85% in FY2023 (-1885.48 pp), -3460.38% in FY2022 (+6524.87 pp) and -9985.25% in FY2021 (+93975.31 pp).
- The Q2 2026 figure represents the highest quarterly Net Margin since Q4 2017.
- Year-over-year, Net Margin increased in three of the last four quarters, with an average year-over-year change of +6836.45 percentage points.
- The fastest year-over-year change in Net Margin over five years came in Q1 2026 (a gain of 25616.17 percentage points), and the weakest in Q1 2025 (a drop of 16349.39 percentage points).
- Business Quant data shows CRNX's Net Margin at -1191.03% (Q1 2026), -1993.43% (Q4 2025) and -90972.73% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 21.86% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 21.27% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -8.04% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 22.61% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 18.81% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 23.62% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -134.51% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | -1.65% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 32.99% |
| 10 | Crinetics Pharmaceuticals | 8.99 Bn | 8.99 Bn | 24.96 Mn | -481.15% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -481.15% |
| Mar 31, 2026 | -1,191.03% |
| Dec 31, 2025 | -1,993.43% |
| Sep 30, 2025 | -90,972.73% |
| Jun 30, 2025 | -11,216.00% |
| Mar 31, 2025 | -26,807.20% |
| Jun 30, 2024 | -18,560.15% |
| Mar 31, 2024 | -10,457.81% |
| Sep 30, 2023 | -16,606.36% |
| Jun 30, 2023 | -5,159.82% |
| Mar 31, 2023 | -1,716.87% |
| Dec 31, 2022 | -6,345.70% |
| Sep 30, 2022 | -9,153.93% |
| Jun 30, 2022 | -9,652.62% |
| Mar 31, 2022 | -1,105.94% |
| Dec 31, 2021 | -2,856.59% |
| Mar 31, 2020 | -24,450.70% |
| Dec 31, 2019 | -4,532.40% |
| Sep 30, 2019 | -2,857.43% |
| Mar 31, 2019 | -2,456.68% |
Crinetics Pharmaceuticals Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=CRNX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "CRNX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=CRNX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();