Crinetics Pharmaceuticals (CRNX) EBITDA Margin (2017 - 2026)

Crinetics Pharmaceuticals' quarterly EBITDA Margin came in at 1220.09% in Q1 2026, up 2529930.0% year-on-year from N/an in Q1 2025, and up 38.96% quarter-over-quarter from 1998.77% in Q4 2025.

Crinetics Pharmaceuticals has reported EBITDA Margin for 10 years, with the latest figure at 1220.09% in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA Margin rose 2529930.0% year-over-year to 1220.09%; the trailing twelve-month figure through Mar 2026 stood at 2765.2% (up 4018217.0% YoY), and the FY2025 full-year result was 6034.5%, up 2268754.0% from the prior year.
  • EBITDA Margin for Q1 2026 stood at 1220.09%, up from 1998.77% in the prior quarter.
  • The five-year high for EBITDA Margin was 1163.75% in Q1 2022, with the low at 90572.03% in Q3 2025.
  • Average EBITDA Margin over 5 years is 15049.55%, with a median of 9717.66% recorded in 2022.
  • Year-over-year, EBITDA Margin plunged 1593236 bps in 2025 and soared 2529930 bps in 2026.
  • Tracing CRNX's EBITDA Margin over 5 years: stood at 6193.51% in 2022, then sank by 164 bps to 16363.58% in 2023, then decreased by 14 bps to 18645.36% in 2024, then soared by 89 bps to 1998.77% in 2025, then jumped by 39 bps to 1220.09% in 2026.
  • The last three EBITDA Margin figures came in at 1220.09% (Q1 2026), 1998.77% (Q4 2025), and 90572.03% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 38.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 17.24%
10 Crinetics Pharmaceuticals 3.59 Bn 3.59 Bn 10.53 Mn -1,220.09%

Historic Data

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DateValue
Mar 31, 2026 -1,220.09%
Dec 31, 2025 -1,998.77%
Sep 30, 2025 -90,572.03%
Jun 30, 2025 -11,252.96%
Mar 31, 2025 -26,519.39%
Jun 30, 2024 -18,645.36%
Mar 31, 2024 -10,587.03%
Sep 30, 2023 -16,363.58%
Jun 30, 2023 -5,077.94%
Mar 31, 2023 -1,663.98%
Dec 31, 2022 -6,193.51%
Sep 30, 2022 -9,457.64%
Jun 30, 2022 -9,977.68%
Mar 31, 2022 -1,163.75%
Dec 31, 2021 -2,890.91%
Dec 31, 2020 30,507.04%
Mar 31, 2020 -24,423.94%
Dec 31, 2019 -4,547.98%
Sep 30, 2019 -2,864.55%
Mar 31, 2019 -2,433.79%
Dec 31, 2018 -1,079.90%
Sep 30, 2018 -1,384.67%
Jun 30, 2018 -847.49%
Mar 31, 2018 -1,236.20%
Dec 31, 2017 -473.67%
Sep 30, 2017 -370.94%
Jun 30, 2017 -197.48%