Crinetics Pharmaceuticals (CRNX) EBITDA Margin (2017 - 2026)
Crinetics Pharmaceuticals' EBITDA Margin came in at -523.08% for Q2 2026, up 11906.90 percentage points from -12429.97% a year earlier and up 773.91 percentage points from the prior quarter.
Crinetics Pharmaceuticals (CRNX) EBITDA Margin (2017 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Crinetics Pharmaceuticals reported EBITDA Margin of -1292.46%, up 28852.44 percentage points year-over-year; for FY2025, it was -6664.23%, up 25681.20 percentage points from FY2024.
- EBITDA Margin carries a five-year change of +97568.17 percentage points (FY2020 to FY2025).
- Going back by year, EBITDA Margin was -32345.43% in FY2024 (-26825.62 pp), -5519.81% in FY2023 (-1996.50 pp), -3523.31% in FY2022 (+6382.07 pp) and -9905.38% in FY2021 (+94327.01 pp).
- The Q2 2026 figure represents the highest quarterly EBITDA Margin since Q4 2017.
- Year-over-year, EBITDA Margin increased in three of the last four quarters, with an average year-over-year change of +7538.42 percentage points.
- The fastest year-over-year change in EBITDA Margin over five years came in Q1 2026 (a gain of 29306.90 percentage points), and the weakest in Q1 2025 (a drop of 19189.03 percentage points).
- Business Quant data shows CRNX's EBITDA Margin at -1296.98% (Q1 2026), -2153.42% (Q4 2025) and -99002.80% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 35.95% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 49.01% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | 6.02% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | - |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 33.11% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 46.01% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -124.26% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 39.16% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 39.10% |
| 10 | Crinetics Pharmaceuticals | 8.99 Bn | 8.99 Bn | 24.96 Mn | -523.08% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -523.08% |
| Mar 31, 2026 | -1,296.98% |
| Dec 31, 2025 | -2,153.42% |
| Sep 30, 2025 | -99,002.80% |
| Jun 30, 2025 | -12,429.97% |
| Mar 31, 2025 | -30,603.88% |
| Jun 30, 2024 | -20,558.90% |
| Mar 31, 2024 | -11,414.84% |
| Sep 30, 2023 | -16,966.47% |
| Jun 30, 2023 | -5,335.53% |
| Mar 31, 2023 | -1,780.33% |
| Dec 31, 2022 | -6,667.98% |
| Sep 30, 2022 | -9,433.62% |
| Jun 30, 2022 | -9,756.26% |
| Mar 31, 2022 | -1,072.72% |
| Dec 31, 2021 | -2,843.51% |
| Mar 31, 2020 | -24,714.08% |
| Dec 31, 2019 | -4,668.22% |
| Sep 30, 2019 | -2,970.50% |
| Mar 31, 2019 | -2,682.29% |
Crinetics Pharmaceuticals EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CRNX&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "CRNX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=CRNX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();