Curis (CRIS) Gross Margin (2012 - 2025)
Curis' (CRIS) quarterly Gross Margin came in at 100.0% in Q4 2025, up 51.0% YoY from 66.23% in Q4 2024, and little changed on a QoQ basis from 99.53% in Q3 2025.
Curis (CRIS) Gross Margin (2012 - 2025) Analysis & Trends
Curis (CRIS) has 14 years of Gross Margin data on file, last reported at 100.0% in Q4 2025.
- Quarterly Gross Margin rose 51.0% year-over-year to 100.0% in Q4 2025, while the trailing twelve-month figure through Mar 2026 was 99.56% (up 14.0% YoY) and the FY2025 annual result came in at 99.52%, up 42.0% from the prior year.
- Gross Margin was little changed at 100.0% in Q4 2025, from 99.53% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 100.0% in Q4 2025 to a low of 94.93% in Q2 2021.
- A 5-year average of 97.7% and a median of 97.94% in 2023 frame the typical range for Gross Margin.
- Annual changes were most pronounced in 2022 — Gross Margin jumped 332 bps — and 2023, when it plunged 161 bps.
- Tracing CRIS's Gross Margin over 5 years: stood at 94.99% in 2021, then grew by 1 bps to 96.05% in 2022, then advanced by 2 bps to 98.0% in 2023, then climbed by 2 bps to 99.49% in 2024, then advanced by 1 bps to 100.0% in 2025.
- The last three Gross Margin figures came in at 100.0% (Q4 2025), 99.53% (Q3 2025), and 99.42% (Q2 2025), per Business Quant data.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 139.47 Bn | 131.61 Bn | 2.84 Bn | 85.33% |
| 2 | Regeneron Pharmaceuticals | 86.36 Bn | 78.37 Bn | 3.93 Bn | 91.59% |
| 3 | Argenx Se | 65.16 Bn | 59.98 Bn | 1.37 Bn | 90.43% |
| 4 | Moderna | 58.99 Bn | 53.85 Bn | 52.00 Mn | 35.86% |
| 5 | BeOne Medicines | 42.08 Bn | 36.98 Bn | 1.53 Bn | 89.76% |
| 6 | Alnylam Pharmaceuticals | 31.74 Bn | 28.43 Bn | 992.69 Mn | 76.90% |
| 7 | BioNTech SE | 28.01 Bn | 9.61 Bn | 668.28 Mn | 63.27% |
| 8 | Insmed | 27.50 Bn | 26.34 Bn | 358.27 Mn | 84.20% |
| 9 | Royalty Pharma | 27.28 Bn | 26.45 Bn | - | - |
| 10 | Curis | 3.33 Mn | -2.28 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 100.00% |
| Sep 30, 2025 | 99.53% |
| Jun 30, 2025 | 99.42% |
| Mar 31, 2025 | 99.41% |
| Dec 31, 2024 | 99.49% |
| Sep 30, 2024 | 99.25% |
| Jun 30, 2024 | 99.53% |
| Mar 31, 2024 | 97.75% |
| Dec 31, 2023 | 98.00% |
| Sep 30, 2023 | 97.88% |
| Jun 30, 2023 | 96.63% |
| Mar 31, 2023 | 98.96% |
| Dec 31, 2022 | 96.05% |
| Sep 30, 2022 | 97.81% |
| Jun 30, 2022 | 98.24% |
| Mar 31, 2022 | 96.01% |
| Dec 31, 2021 | 94.99% |
| Sep 30, 2021 | 95.03% |
| Jun 30, 2021 | 94.93% |
| Mar 31, 2021 | 95.02% |