Caris Life Sciences (CAI) Operating Margin (2024 - 2026)
Caris Life Sciences' (CAI) quarterly Operating Margin came in at 2.44% in Q1 2026, up 5037.0% year-on-year from 0.05% in Q1 2025, and down 91.91% quarter-over-quarter from 30.19% in Q4 2025.
Caris Life Sciences (CAI) Operating Margin (2024 - 2026) Analysis & Trends
Caris Life Sciences' Operating Margin history runs 3 years deep, the most recent figure standing at 2.44% for Q1 2026.
- On a quarterly basis, Operating Margin rose 5037.0% year-over-year to 2.44% in Q1 2026; TTM through Mar 2026 was 11.94%, a 6119.0% increase from a year earlier, with the FY2025 full-year figure at 5.56%, up 6792.0% from the prior year.
- Operating Margin retreated to 2.44% in Q1 2026 per CAI's latest filing, from 30.19% in the prior quarter.
- Across five years, Operating Margin topped out at 30.19% in Q4 2025 and bottomed at 66.98% in Q2 2024.
- The 3-year median for Operating Margin is 19.22% (2024), against an average of 20.69%.
- Across the five-year window, Operating Margin jumped 7493 bps in 2025 and surged 5037 bps in 2026, its largest moves.
- Year by year, Operating Margin stood at 28.52% in 2024, then soared by 206 bps to 30.19% in 2025, then tumbled by 92 bps to 2.44% in 2026.
- Per Business Quant, the three latest CAI Operating Margin figures stand at 2.44% (Q1 2026), 30.19% (Q4 2025), and 15.05% (Q3 2025).
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 16.51% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 38.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 17.83% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 31.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Caris Life Sciences | 4.42 Bn | 3.60 Bn | 214.23 Mn | 2.44% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 2.44% |
| Dec 31, 2025 | 30.19% |
| Sep 30, 2025 | 15.05% |
| Jun 30, 2025 | -9.92% |
| Mar 31, 2025 | -47.93% |
| Dec 31, 2024 | -28.52% |
| Sep 30, 2024 | -59.87% |
| Jun 30, 2024 | -66.98% |