Caris Life Sciences (CAI) Operating Margin (2024 - 2026)

Caris Life Sciences (CAI) recorded quarterly Operating Margin of 2.44% in Q1 2026, down 91.91% quarter-over-quarter from 30.19% in Q4 2025, and up 5037.0% on a YoY basis from 0.05% in Q1 2025.

Caris Life Sciences (CAI) Operating Margin (2024 - 2026) Analysis & Trends

Caris Life Sciences' Operating Margin history runs 3 years deep, the most recent figure standing at 2.44% for Q1 2026.

  • In Q1 2026, Operating Margin rose 5037.0% year-over-year to 2.44%; the TTM figure through Mar 2026 stood at 11.94% (up 6119.0% YoY), while the FY2025 annual figure was 5.56%, up 6792.0% from the prior year.
  • Operating Margin was 2.44% for Q1 2026 at Caris Life Sciences, down from 30.19% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 30.19% in Q4 2025 to a low of 66.98% in Q2 2024.
  • Historically, Operating Margin has averaged 20.69% across 3 years, with a median of 19.22% in 2024.
  • The sharpest annual moves came in 2025 and 2026: Operating Margin surged 7493 bps in 2025, then soared 5037 bps in 2026.
  • A 3-year view of Operating Margin shows it stood at 28.52% in 2024, then soared by 206 bps to 30.19% in 2025, then sank by 92 bps to 2.44% in 2026.
  • The last three Operating Margin figures came in at 2.44% (Q1 2026), 30.19% (Q4 2025), and 15.05% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -6.43%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 38.10%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Caris Life Sciences 5.22 Bn 4.40 Bn 171.13 Mn 2.44%

Historic Data

Download Data
DateValue
Mar 31, 2026 2.44%
Dec 31, 2025 30.19%
Sep 30, 2025 15.05%
Jun 30, 2025 -9.92%
Mar 31, 2025 -47.93%
Dec 31, 2024 -28.52%
Sep 30, 2024 -59.87%
Jun 30, 2024 -66.98%