BioNTech SE (BNTX) Gross Margin (2018 - 2025)
BioNTech SE (BNTX) reported Gross Margin of 63.27% for Q4 2025, down 1627.0% on a YoY basis from 4.14% in Q4 2024, and down 29.89% sequentially from 90.24% in Q3 2025.
BioNTech SE (BNTX) Gross Margin (2018 - 2025) Analysis & Trends
BioNTech SE (BNTX) has 8 years of Gross Margin data on file, last reported at 63.27% in Q4 2025.
- For the quarter ending Q4 2025, Gross Margin fell 1627.0% year-over-year to 63.27%; the trailing twelve-month figure through Dec 2025 stood at 77.83% (down 254.0% YoY), and the FY2025 full-year result was 77.64%, down 269.0% from the prior year.
- Gross Margin retreated to 63.27% in Q4 2025, from 90.24% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 100.0% in Q4 2021 to a low of 2.86% in Q2 2023.
- A 5-year average of 75.63% and a median of 79.9% in 2021 frame the typical range for Gross Margin.
- Across the five-year window, Gross Margin sank 7322 bps in 2023 and soared 5067 bps in 2024, its largest moves.
- Tracing BNTX's Gross Margin over 5 years: stood at 100.0% in 2021, then fell by 4 bps to 95.71% in 2022, then fell by 8 bps to 87.89% in 2023, then dropped by 10 bps to 79.54% in 2024, then decreased by 20 bps to 63.27% in 2025.
- Business Quant data shows BNTX's Gross Margin at 63.27% in Q4 2025, 90.24% in Q3 2025, and 70.71% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 88.95% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 90.68% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | BioNTech SE | 22.13 Bn | 22.13 Bn | 668.28 Mn | 63.27% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 63.27% |
| Sep 30, 2025 | 90.24% |
| Jun 30, 2025 | 70.71% |
| Mar 31, 2025 | 54.16% |
| Dec 31, 2024 | 79.54% |
| Sep 30, 2024 | 85.63% |
| Jun 30, 2024 | 53.54% |
| Mar 31, 2024 | 68.50% |
| Dec 31, 2023 | 87.89% |
| Sep 30, 2023 | 81.93% |
| Jun 30, 2023 | 2.86% |
| Mar 31, 2023 | 92.48% |
| Dec 31, 2022 | 95.71% |
| Sep 30, 2022 | 78.25% |
| Jun 30, 2022 | 76.08% |
| Mar 31, 2022 | 79.70% |
| Dec 31, 2021 | 100.00% |
| Sep 30, 2021 | 80.10% |
| Jun 30, 2021 | 83.35% |
| Mar 31, 2021 | 88.62% |