BioNTech SE (BNTX) Gross Margin (2018 - 2025)
BioNTech SE's (BNTX) quarterly Gross Margin came in at 63.27% in Q4 2025, down 3672.0% year-on-year from 1.77% in Q4 2024, and down 29.89% quarter-over-quarter from 90.24% in Q3 2025.
BioNTech SE (BNTX) Gross Margin (2018 - 2025) Analysis & Trends
BioNTech SE has disclosed Gross Margin across 8 years of filings, most recently posting 63.27% for Q4 2025.
- Gross Margin for Q4 2025 came in at 63.27%, down 3672.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 74.31% (down 2567.0% YoY), and the FY2025 annual result was 754.59%, down 83492.0% from the prior year.
- Gross Margin came in at 63.27% for Q4 2025 at BioNTech SE, down from 90.24% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 99.99% in Q4 2024 to a low of 82891.6% in Q1 2021.
- The 5-year median for Gross Margin is 79.9% (2021), against an average of 4166.71%.
- Across the five-year window, Gross Margin sank 8297038 bps in 2021 and soared 8297130 bps in 2022, its largest moves.
- BioNTech SE's Gross Margin stood at 89.46% in 2021, then increased by 7 bps to 95.71% in 2022, then retreated by 8 bps to 87.89% in 2023, then increased by 14 bps to 99.99% in 2024, then slumped by 37 bps to 63.27% in 2025.
- The last three Gross Margin figures came in at 63.27% (Q4 2025), 90.24% (Q3 2025), and 879.49% (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 79.04% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 86.85% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | BioNTech SE | 27.38 Bn | 10.07 Bn | 668.28 Mn | 63.27% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 63.27% |
| Sep 30, 2025 | 90.24% |
| Jun 30, 2025 | -879.49% |
| Mar 31, 2025 | -261.21% |
| Dec 31, 2024 | 99.99% |
| Sep 30, 2024 | 85.63% |
| Jun 30, 2024 | 53.54% |
| Mar 31, 2024 | -542.39% |
| Dec 31, 2023 | 87.89% |
| Sep 30, 2023 | 81.93% |
| Jun 30, 2023 | 2.86% |
| Mar 31, 2023 | 92.48% |
| Dec 31, 2022 | 95.71% |
| Sep 30, 2022 | 78.25% |
| Jun 30, 2022 | 76.08% |
| Mar 31, 2022 | 79.70% |
| Dec 31, 2021 | 89.46% |
| Sep 30, 2021 | 80.10% |
| Jun 30, 2021 | 83.35% |
| Mar 31, 2021 | -82,891.60% |