BioNTech SE (BNTX) Gross Margin (2018 - 2025)

BioNTech SE's (BNTX) quarterly Gross Margin came in at 63.27% in Q4 2025, down 3672.0% year-on-year from 1.77% in Q4 2024, and down 29.89% quarter-over-quarter from 90.24% in Q3 2025.

BioNTech SE (BNTX) Gross Margin (2018 - 2025) Analysis & Trends

BioNTech SE has disclosed Gross Margin across 8 years of filings, most recently posting 63.27% for Q4 2025.

  • Gross Margin for Q4 2025 came in at 63.27%, down 3672.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 74.31% (down 2567.0% YoY), and the FY2025 annual result was 754.59%, down 83492.0% from the prior year.
  • Gross Margin came in at 63.27% for Q4 2025 at BioNTech SE, down from 90.24% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 99.99% in Q4 2024 to a low of 82891.6% in Q1 2021.
  • The 5-year median for Gross Margin is 79.9% (2021), against an average of 4166.71%.
  • Across the five-year window, Gross Margin sank 8297038 bps in 2021 and soared 8297130 bps in 2022, its largest moves.
  • BioNTech SE's Gross Margin stood at 89.46% in 2021, then increased by 7 bps to 95.71% in 2022, then retreated by 8 bps to 87.89% in 2023, then increased by 14 bps to 99.99% in 2024, then slumped by 37 bps to 63.27% in 2025.
  • The last three Gross Margin figures came in at 63.27% (Q4 2025), 90.24% (Q3 2025), and 879.49% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 79.04%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 86.85%
9 Abivax 91.96 Bn 91.96 Bn - -
10 BioNTech SE 27.38 Bn 10.07 Bn 668.28 Mn 63.27%

Historic Data

Download Data
DateValue
Dec 31, 2025 63.27%
Sep 30, 2025 90.24%
Jun 30, 2025 -879.49%
Mar 31, 2025 -261.21%
Dec 31, 2024 99.99%
Sep 30, 2024 85.63%
Jun 30, 2024 53.54%
Mar 31, 2024 -542.39%
Dec 31, 2023 87.89%
Sep 30, 2023 81.93%
Jun 30, 2023 2.86%
Mar 31, 2023 92.48%
Dec 31, 2022 95.71%
Sep 30, 2022 78.25%
Jun 30, 2022 76.08%
Mar 31, 2022 79.70%
Dec 31, 2021 89.46%
Sep 30, 2021 80.10%
Jun 30, 2021 83.35%
Mar 31, 2021 -82,891.60%