BillionToOne (BLLN) Operating Margin (2024 - 2026)

BillionToOne's (BLLN) quarterly Operating Margin came in at 16.45% in Q1 2026, up 2038.0% year-on-year from 0.77% in Q1 2025, and up 52.97% quarter-over-quarter from 10.76% in Q4 2025.

BillionToOne (BLLN) Operating Margin (2024 - 2026) Analysis & Trends

BillionToOne has disclosed Operating Margin across 3 years of filings, most recently posting 16.45% for Q1 2026.

  • Operating Margin for Q1 2026 came in at 16.45%, up 2038.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 10.23% (changed N/A YoY), and the FY2025 annual result was 5.25%, up 3615.0% from the prior year.
  • Operating Margin came in at 16.45% for Q1 2026 at BillionToOne, up from 10.76% in the prior quarter.
  • In the past five years, Operating Margin ranged from a high of 16.45% in Q1 2026 to a low of 32.88% in Q3 2024.
  • The 3-year median for Operating Margin is 3.42% (2025), against an average of 4.0%.
  • Across the five-year window, Operating Margin surged 4442 bps in 2025 and surged 2038 bps in 2026, its largest moves.
  • BillionToOne's Operating Margin stood at 25.94% in 2024, then surged by 141 bps to 10.76% in 2025, then soared by 53 bps to 16.45% in 2026.
  • The last three Operating Margin figures came in at 16.45% (Q1 2026), 10.76% (Q4 2025), and 11.53% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Operating Margin (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn -3.71%
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 16.93%
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 22.58%
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 31.78%
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 21.74%
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 12.38%
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn -13.42%
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 19.16%
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 25.23%
10 BillionToOne 4.33 Bn 3.79 Bn 79.10 Mn 16.45%

Historic Data

Download Data
DateValue
Mar 31, 2026 16.45%
Dec 31, 2025 10.76%
Sep 30, 2025 11.53%
Mar 31, 2025 -3.93%
Dec 31, 2024 -25.94%
Sep 30, 2024 -32.88%