Biofrontera (BFRI) Gross Margin (2020 - 2025)
Biofrontera's (BFRI) quarterly Gross Margin came in at 82.4% in Q4 2025, up 2437.0% year-on-year from 3.25% in Q4 2024, and up 16.5% quarter-over-quarter from 70.74% in Q3 2025.
Biofrontera (BFRI) Gross Margin (2020 - 2025) Analysis & Trends
Biofrontera's Gross Margin history runs 6 years deep, the most recent figure standing at 82.4% for Q4 2025.
- On a quarterly basis, Gross Margin rose 2437.0% year-over-year to 82.4% in Q4 2025; TTM through Dec 2025 was 73.71%, a 2356.0% increase from a year earlier, with the FY2025 full-year figure at 73.71%, up 2357.0% from the prior year.
- Gross Margin advanced to 82.4% in Q4 2025 per BFRI's latest filing, from 70.74% in the prior quarter.
- Across five years, Gross Margin topped out at 112.8% in Q4 2023 and bottomed at 72.27% in Q4 2022.
- The 5-year median for Gross Margin is 76.57% (2025), against an average of 70.47%.
- Across the five-year window, Gross Margin slumped 17349 bps in 2022 and soared 18507 bps in 2023, its largest moves.
- Year by year, Gross Margin stood at 101.22% in 2021, then sank by 171 bps to 72.27% in 2022, then surged by 256 bps to 112.8% in 2023, then tumbled by 49 bps to 58.03% in 2024, then jumped by 42 bps to 82.4% in 2025.
- Per Business Quant, the three latest BFRI Gross Margin figures stand at 82.4% (Q4 2025), 70.74% (Q3 2025), and 70.74% (Q2 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Haleon | 87.22 Bn | 85.35 Bn | - | - |
| 2 | Teva Pharmaceutical Industries | 39.60 Bn | 35.87 Bn | 1.97 Bn | 49.52% |
| 3 | Zoetis | 31.46 Bn | 29.52 Bn | 1.62 Bn | 71.66% |
| 4 | Takeda Pharmaceutical | 26.49 Bn | 22.44 Bn | 4.39 Bn | 62.93% |
| 5 | United Therapeutics | 23.03 Bn | 20.88 Bn | 648.10 Mn | 82.93% |
| 6 | Universe Pharmaceuticals | 23.03 Bn | -10.56 Bn | - | - |
| 7 | Viatris | 20.90 Bn | 19.09 Bn | 1.16 Bn | 32.97% |
| 8 | Neurocrine Biosciences | 17.50 Bn | 16.19 Bn | 800.70 Mn | 98.31% |
| 9 | Elanco Animal Health | 12.33 Bn | 11.91 Bn | 785.00 Mn | 57.26% |
| 10 | Biofrontera | 12.70 Mn | 6.29 Mn | 14.09 Mn | 82.40% |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 82.40% |
| Sep 30, 2025 | 70.74% |
| Jun 30, 2025 | 70.74% |
| Mar 31, 2025 | 61.95% |
| Dec 31, 2024 | 58.03% |
| Sep 30, 2024 | 45.88% |
| Jun 30, 2024 | 44.61% |
| Mar 31, 2024 | 47.98% |
| Dec 31, 2023 | 112.80% |
| Sep 30, 2023 | 98.93% |
| Jun 30, 2023 | 52.60% |
| Mar 31, 2023 | 47.93% |
| Dec 31, 2022 | -72.27% |
| Sep 30, 2022 | 97.73% |
| Jun 30, 2022 | 96.59% |
| Mar 31, 2022 | 98.21% |
| Dec 31, 2021 | 101.22% |
| Sep 30, 2021 | 99.05% |
| Jun 30, 2021 | 97.69% |
| Mar 31, 2021 | 96.56% |