Biofrontera (BFRI) Gross Margin (2020 - 2025)

Biofrontera's (BFRI) quarterly Gross Margin came in at 82.4% in Q4 2025, up 2437.0% year-on-year from 3.25% in Q4 2024, and up 16.5% quarter-over-quarter from 70.74% in Q3 2025.

Biofrontera (BFRI) Gross Margin (2020 - 2025) Analysis & Trends

Biofrontera's Gross Margin history runs 6 years deep, the most recent figure standing at 82.4% for Q4 2025.

  • On a quarterly basis, Gross Margin rose 2437.0% year-over-year to 82.4% in Q4 2025; TTM through Dec 2025 was 73.71%, a 2356.0% increase from a year earlier, with the FY2025 full-year figure at 73.71%, up 2357.0% from the prior year.
  • Gross Margin advanced to 82.4% in Q4 2025 per BFRI's latest filing, from 70.74% in the prior quarter.
  • Across five years, Gross Margin topped out at 112.8% in Q4 2023 and bottomed at 72.27% in Q4 2022.
  • The 5-year median for Gross Margin is 76.57% (2025), against an average of 70.47%.
  • Across the five-year window, Gross Margin slumped 17349 bps in 2022 and soared 18507 bps in 2023, its largest moves.
  • Year by year, Gross Margin stood at 101.22% in 2021, then sank by 171 bps to 72.27% in 2022, then surged by 256 bps to 112.8% in 2023, then tumbled by 49 bps to 58.03% in 2024, then jumped by 42 bps to 82.4% in 2025.
  • Per Business Quant, the three latest BFRI Gross Margin figures stand at 82.4% (Q4 2025), 70.74% (Q3 2025), and 70.74% (Q2 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Haleon 87.22 Bn 85.35 Bn - -
2 Teva Pharmaceutical Industries 39.60 Bn 35.87 Bn 1.97 Bn 49.52%
3 Zoetis 31.46 Bn 29.52 Bn 1.62 Bn 71.66%
4 Takeda Pharmaceutical 26.49 Bn 22.44 Bn 4.39 Bn 62.93%
5 United Therapeutics 23.03 Bn 20.88 Bn 648.10 Mn 82.93%
6 Universe Pharmaceuticals 23.03 Bn -10.56 Bn - -
7 Viatris 20.90 Bn 19.09 Bn 1.16 Bn 32.97%
8 Neurocrine Biosciences 17.50 Bn 16.19 Bn 800.70 Mn 98.31%
9 Elanco Animal Health 12.33 Bn 11.91 Bn 785.00 Mn 57.26%
10 Biofrontera 12.70 Mn 6.29 Mn 14.09 Mn 82.40%

Historic Data

Download Data
DateValue
Dec 31, 2025 82.40%
Sep 30, 2025 70.74%
Jun 30, 2025 70.74%
Mar 31, 2025 61.95%
Dec 31, 2024 58.03%
Sep 30, 2024 45.88%
Jun 30, 2024 44.61%
Mar 31, 2024 47.98%
Dec 31, 2023 112.80%
Sep 30, 2023 98.93%
Jun 30, 2023 52.60%
Mar 31, 2023 47.93%
Dec 31, 2022 -72.27%
Sep 30, 2022 97.73%
Jun 30, 2022 96.59%
Mar 31, 2022 98.21%
Dec 31, 2021 101.22%
Sep 30, 2021 99.05%
Jun 30, 2021 97.69%
Mar 31, 2021 96.56%