Bicycle Therapeutics (BCYC) Return on Sales (2018 - 2026)

Bicycle Therapeutics' (BCYC) quarterly Return on Sales came in at 0.8% in Q2 2026, down 53.0% YoY from 1.7% in Q2 2025, and down 16.66% on a QoQ basis from 0.69% in Q1 2026.

Bicycle Therapeutics (BCYC) Return on Sales (2018 - 2026) Analysis & Trends

Bicycle Therapeutics (BCYC) has 9 years of Return on Sales data on file, last reported at 0.8% in Q2 2026.

  • Quarterly Return on Sales fell 53.0% year-over-year to 0.8% in Q2 2026, while the trailing twelve-month figure through Jun 2026 was 0.02% (up 11.0% YoY) and the FY2025 annual result came in at 0.02%, up 3.0% from the prior year.
  • Return on Sales retreated to 0.8% in Q2 2026, from 0.69% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.01% in Q4 2025 to a low of 0.8% in Q2 2026.
  • A 5-year average of 0.16% and a median of 0.08% in 2022 frame the typical range for Return on Sales.
  • Annual changes were most pronounced in 2025 — Return on Sales grew 16 bps — and 2026, when it sank 63 bps.
  • Tracing BCYC's Return on Sales over 5 years: stood at 0.04% in 2022, then tumbled by 111 bps to 0.09% in 2023, then sank by 67 bps to 0.16% in 2024, then jumped by 104 bps to 0.01% in 2025, then slumped by 13782 bps to 0.8% in 2026.
  • The last three Return on Sales figures came in at 0.8% (Q2 2026), 0.69% (Q1 2026), and 0.01% (Q4 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Bicycle Therapeutics 272.28 Mn 272.28 Mn - -0.80%

Historic Data

Download Data
DateValue
Jun 30, 2026 -0.80%
Mar 31, 2026 -0.69%
Dec 31, 2025 0.04%
Sep 30, 2025 -0.05%
Jun 30, 2025 -0.27%
Mar 31, 2025 -0.06%
Dec 31, 2024 -0.14%
Sep 30, 2024 -0.19%
Jun 30, 2024 -0.04%
Mar 31, 2024 -0.03%
Dec 31, 2023 0.25%
Sep 30, 2023 -0.09%
Jun 30, 2023 -0.04%
Mar 31, 2023 -0.08%
Dec 31, 2022 -0.04%
Sep 30, 2022 -0.09%
Jun 30, 2022 -0.05%
Mar 31, 2022 -0.07%
Dec 31, 2021 -0.11%
Sep 30, 2021 -0.03%