Bicycle Therapeutics (BCYC) Return on Sales (2018 - 2026)

Bicycle Therapeutics' Return on Sales history runs 9 years deep, the most recent figure standing at 0.69% for Q1 2026.

• Quarterly Return on Sales fell 62.0% year-over-year to 0.69% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 0.0% (up 8.0% YoY) and the FY2025 annual result came in at 0.0%, up 5.0% from the prior year.
• Return on Sales was 0.69% for Q1 2026 at Bicycle Therapeutics, down from 0.04% in the prior quarter.
• Across five years, Return on Sales topped out at 0.25% in Q4 2023 and bottomed at 0.69% in Q1 2026.
• A 5-year average of 0.1% and a median of 0.06% in 2025 frame the typical range for Return on Sales.
• Annual changes were most pronounced in 2023 — Return on Sales grew 29 bps — and 2026, when it slumped 62 bps.
• Bicycle Therapeutics' Return on Sales stood at 0.04% in 2022, then jumped by 758 bps to 0.25% in 2023, then tumbled by 156 bps to 0.14% in 2024, then jumped by 131 bps to 0.04% in 2025, then sank by 1708 bps to 0.69% in 2026.
• Business Quant data shows BCYC's Return on Sales at 0.69% in Q1 2026, 0.04% in Q4 2025, and 0.05% in Q3 2025.