Bicycle Therapeutics (BCYC) Return on Sales (2018 - 2026)

Bicycle Therapeutics (BCYC) reported Return on Sales of 0.69% for Q1 2026, down 62.0% on a YoY basis from 1.8% in Q1 2025, and down 12147.52% quarter-over-quarter from 0.01% in Q4 2025.

Bicycle Therapeutics (BCYC) Return on Sales (2018 - 2026) Analysis & Trends

Bicycle Therapeutics has reported Return on Sales for 9 years, with the latest figure at 0.69% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Sales fell 62.0% year-over-year to 0.69%; the trailing twelve-month figure through Mar 2026 stood at 0.04% (down 3.0% YoY), and the FY2025 full-year result was 0.03%, down 3.0% from the prior year.
  • Return on Sales for Q1 2026 stood at 0.69%, down from 0.01% in the prior quarter.
  • The five-year high for Return on Sales was 0.34% in Q4 2024, with the low at 0.69% in Q1 2026.
  • Historically, Return on Sales has averaged 0.09% across 5 years, with a median of 0.06% in 2025.
  • Annual changes were most pronounced in 2024 — Return on Sales jumped 44 bps — and 2026, when it tumbled 62 bps.
  • Bicycle Therapeutics' Return on Sales stood at 0.04% in 2022, then sank by 160 bps to 0.1% in 2023, then surged by 447 bps to 0.34% in 2024, then tumbled by 102 bps to 0.01% in 2025, then sank by 12148 bps to 0.69% in 2026.
  • The last three Return on Sales figures came in at 0.69% (Q1 2026), 0.01% (Q4 2025), and 0.05% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.00%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 0.00%
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 0.00%
9 Abivax 91.96 Bn 91.96 Bn - -
10 Bicycle Therapeutics 278.04 Mn 278.04 Mn - -0.69%

Historic Data

Download Data
DateValue
Mar 31, 2026 -0.69%
Dec 31, 2025 -0.01%
Sep 30, 2025 -0.05%
Jun 30, 2025 -0.27%
Mar 31, 2025 -0.06%
Dec 31, 2024 0.34%
Sep 30, 2024 -0.19%
Jun 30, 2024 -0.04%
Mar 31, 2024 -0.03%
Dec 31, 2023 -0.10%
Sep 30, 2023 -0.09%
Jun 30, 2023 -0.04%
Mar 31, 2023 -0.08%
Dec 31, 2022 -0.04%
Sep 30, 2022 -0.09%
Jun 30, 2022 -0.03%
Mar 31, 2022 -0.07%
Dec 31, 2021 -0.12%
Sep 30, 2021 -0.03%
Jun 30, 2021 -0.10%