Bicycle Therapeutics (BCYC) Research & Development (2018 - 2026)
Bicycle Therapeutics (BCYC) reported Research & Development of $48.9 million for Q1 2026, down 17.2% on a YoY basis from $59.1 million in Q1 2025, and down 5.54% quarter-over-quarter from $51.8 million in Q4 2025.
Bicycle Therapeutics (BCYC) Research & Development (2018 - 2026) Analysis & Trends
Bicycle Therapeutics has reported Research & Development for 9 years, with the latest figure at $48.9 million in Q1 2026.
- For the quarter ending Q1 2026, Research & Development fell 17.2% year-over-year to $48.9 million; the trailing twelve-month figure through Mar 2026 stood at $230.1 million (up 16.72% YoY), and the FY2025 full-year result was $240.3 million, up 38.92% from the prior year.
- Research & Development for Q1 2026 stood at $48.9 million, down from $51.8 million in the prior quarter.
- The five-year high for Research & Development was $71.0 million in Q2 2025, with the low at $14.3 million in Q1 2022.
- Historically, Research & Development has averaged $41.2 million across 5 years, with a median of $40.1 million in 2024.
- Annual changes were most pronounced in 2023 — Research & Development soared 125.5% — and 2026, when it declined 17.2%.
- Bicycle Therapeutics' Research & Development stood at $24.7 million in 2022, then soared by 80.82% to $44.7 million in 2023, then advanced by 11.37% to $49.8 million in 2024, then increased by 4.0% to $51.8 million in 2025, then decreased by 5.54% to $48.9 million in 2026.
- The last three Research & Development figures came in at $48.9 million (Q1 2026), $51.8 million (Q4 2025), and $58.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | 4.32 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | 15.66 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | 626,092.00 |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -101.30 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -2.30 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | 1.46 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | 357,444.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 961.60 Mn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -58.00 Mn |
| 10 | Bicycle Therapeutics | 278.04 Mn | 278.04 Mn | - | 48.90 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.90 Mn |
| Dec 31, 2025 | 51.77 Mn |
| Sep 30, 2025 | 58.43 Mn |
| Jun 30, 2025 | 71.03 Mn |
| Mar 31, 2025 | 59.06 Mn |
| Dec 31, 2024 | 49.78 Mn |
| Sep 30, 2024 | 48.27 Mn |
| Jun 30, 2024 | 40.06 Mn |
| Mar 31, 2024 | 34.86 Mn |
| Dec 31, 2023 | 44.70 Mn |
| Sep 30, 2023 | 39.87 Mn |
| Jun 30, 2023 | 39.72 Mn |
| Mar 31, 2023 | 32.21 Mn |
| Dec 31, 2022 | 24.72 Mn |
| Sep 30, 2022 | 22.75 Mn |
| Jun 30, 2022 | 19.85 Mn |
| Mar 31, 2022 | 14.28 Mn |
| Dec 31, 2021 | 12.96 Mn |
| Sep 30, 2021 | 10.51 Mn |
| Jun 30, 2021 | 11.72 Mn |