Axsome Therapeutics (AXSM) Return on Invested Capital [ROIC] (2018 - 2026)
Axsome Therapeutics (AXSM) recorded Return on Invested Capital [ROIC] of -53.48% in Q3 2026, up 27.58 percentage points from -81.07% a year earlier and up 18.96 percentage points from the prior quarter.
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Analysis
Axsome Therapeutics (AXSM) Return on Invested Capital [ROIC] (2018 - 2026) Analysis & Trends
For FY2025, Axsome Therapeutics reported Return on Invested Capital [ROIC] of -64.73%, up 27.75 percentage points from FY2024.
- Across earlier years, Return on Invested Capital [ROIC] came in at -92.48% in FY2024 (-11.54 pp) and -80.94% in FY2023.
- The Q3 2026 figure is the highest quarterly Return on Invested Capital [ROIC] since Q3 2023.
- On a year-over-year basis, Return on Invested Capital [ROIC] has increased for six consecutive quarters, with an average year-over-year change of +12.19 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Invested Capital [ROIC] in the last five years was a gain of 48.01 percentage points in Q4 2025, against a drop of 67.34 percentage points in Q3 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -72.44% (Q2 2026), -66.60% (Q1 2026) and -61.88% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 30.89% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 17.57% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 24.28% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 2.52% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 23.11% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 15.60% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -6.11% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 12.34% |
| 10 | Axsome Therapeutics | 7.41 Bn | 6.15 Bn | 241.89 Mn | -53.48% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -53.48% |
| Jun 30, 2026 | -72.44% |
| Mar 31, 2026 | -66.60% |
| Dec 31, 2025 | -61.88% |
| Sep 30, 2025 | -81.07% |
| Jun 30, 2025 | -92.12% |
| Mar 31, 2025 | -114.45% |
| Dec 31, 2024 | -109.89% |
| Sep 30, 2024 | -110.21% |
| Jun 30, 2024 | -100.74% |
| Mar 31, 2024 | -84.16% |
| Dec 31, 2023 | -56.82% |
| Sep 30, 2023 | -42.87% |
| Jun 30, 2023 | -48.60% |
| Mar 31, 2023 | -63.85% |
| Dec 31, 2019 | -59.71% |
| Sep 30, 2019 | -94.74% |
| Dec 31, 2018 | -170.93% |
API Access
Axsome Therapeutics Return on Invested Capital [ROIC] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-invested-capital-[roic]", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();