Axsome Therapeutics (AXSM) Return on Invested Capital [ROIC] (2023 - 2026)
Axsome Therapeutics (AXSM) recorded Return on Invested Capital [ROIC] of -72.44% in Q2 2026, up 19.68 percentage points from -92.12% a year earlier but down 5.84 percentage points from the prior quarter.
Powered by 
Analysis
Axsome Therapeutics (AXSM) Return on Invested Capital [ROIC] (2023 - 2026) Analysis & Trends
For FY2025, Axsome Therapeutics reported Return on Invested Capital [ROIC] of -64.73%, up 27.75 percentage points from FY2024.
- Across earlier years, Return on Invested Capital [ROIC] came in at -92.48% in FY2024 (-11.54 pp) and -80.94% in FY2023.
- Quarterly Return on Invested Capital [ROIC] has ranged from -114.45% in Q1 2025 to -42.87% in Q3 2023 over the past five years.
- On a year-over-year basis, Return on Invested Capital [ROIC] has increased for five consecutive quarters, with an average year-over-year change of +0.32 percentage points over the last eight quarters.
- Peak year-over-year performance for Return on Invested Capital [ROIC] in the last five years was a gain of 48.01 percentage points in Q4 2025, against a drop of 67.34 percentage points in Q3 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at -66.60% (Q1 2026), -61.88% (Q4 2025) and -81.07% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 37.16% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 16.10% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 18.68% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 3.56% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 21.95% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 28.83% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 14.33% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 13.44% |
| 10 | Axsome Therapeutics | 9.37 Bn | 8.10 Bn | 204.81 Mn | -72.44% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -72.44% |
| Mar 31, 2026 | -66.60% |
| Dec 31, 2025 | -61.88% |
| Sep 30, 2025 | -81.07% |
| Jun 30, 2025 | -92.12% |
| Mar 31, 2025 | -114.45% |
| Dec 31, 2024 | -109.89% |
| Sep 30, 2024 | -110.21% |
| Jun 30, 2024 | -100.74% |
| Mar 31, 2024 | -84.16% |
| Dec 31, 2023 | -56.82% |
| Sep 30, 2023 | -42.87% |
| Jun 30, 2023 | -48.60% |
API Access
Axsome Therapeutics Return on Invested Capital [ROIC] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-invested-capital-[roic]", "ticker": "AXSM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=AXSM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();