Avalo Therapeutics (AVTX) Return on Capital Employed (2015 - 2026)

Avalo Therapeutics (AVTX) posted Return on Capital Employed of 81.97% for Q1 2026, down 21.21% on a QoQ basis from 67.62% in Q4 2025, and down 4570.0% year-over-year from 1.83% in Q1 2025.

Avalo Therapeutics (AVTX) Return on Capital Employed (2015 - 2026) Analysis & Trends

Avalo Therapeutics' Return on Capital Employed history runs 12 years deep, the most recent figure standing at 81.97% for Q1 2026.

  • Quarterly Return on Capital Employed fell 4570.0% year-over-year to 81.97% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 81.97% (down 4570.0% YoY) and the FY2025 annual result came in at 60.44%, up 2639.0% from the prior year.
  • Return on Capital Employed was 81.97% for Q1 2026 at Avalo Therapeutics, down from 67.62% in the prior quarter.
  • Across five years, Return on Capital Employed topped out at 35.81% in Q1 2024 and bottomed at 291.53% in Q4 2022.
  • A 5-year average of 142.21% and a median of 136.2% in 2022 frame the typical range for Return on Capital Employed.
  • Annual changes were most pronounced in 2022 — Return on Capital Employed plunged 17056 bps — and 2024, when it jumped 25543 bps.
  • Avalo Therapeutics' Return on Capital Employed stood at 291.53% in 2022, then surged by 54 bps to 133.33% in 2023, then soared by 56 bps to 58.24% in 2024, then retreated by 16 bps to 67.62% in 2025, then slipped by 21 bps to 81.97% in 2026.
  • Business Quant data shows AVTX's Return on Capital Employed at 81.97% in Q1 2026, 67.62% in Q4 2025, and 56.41% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 67,102.16 Bn 67,101.87 Bn - -31.80%
2 Nanobiotix 1,908.96 Bn 1,908.90 Bn - -
3 Akari Therapeutics 959.56 Bn 959.56 Bn - -107.40%
4 BeOne Medicines 474.03 Bn 469.24 Bn 1.35 Bn 10.46%
5 Vertex Pharmaceuticals 122.13 Bn 114.88 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 70.09 Bn 61.34 Bn 3.31 Bn 10.19%
7 Belite Bio 62.34 Bn 62.34 Bn - -
8 Argenx Se 55.96 Bn 50.77 Bn 1.41 Bn -
9 Alnylam Pharmaceuticals 37.53 Bn 34.52 Bn 959.66 Mn 20.34%
10 Avalo Therapeutics 397.71 Mn 340.56 Mn - -81.97%

Historic Data

Download Data
DateValue
Mar 31, 2026 -81.97%
Dec 31, 2025 -67.62%
Sep 30, 2025 -56.41%
Jun 30, 2025 -48.79%
Mar 31, 2025 -36.27%
Dec 31, 2024 -58.24%
Sep 30, 2024 -147.19%
Jun 30, 2024 -273.95%
Mar 31, 2024 35.81%
Dec 31, 2023 -133.33%
Sep 30, 2023 -137.59%
Jun 30, 2023 -266.06%
Mar 31, 2023 -219.63%
Dec 31, 2022 -291.53%
Sep 30, 2022 -286.69%
Jun 30, 2022 -211.92%
Mar 31, 2022 -136.20%
Dec 31, 2021 -120.97%
Sep 30, 2021 -132.68%
Jun 30, 2021 -183.93%